Values CatLog read from this paper

The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region

PMID 20074540doi:10.1016/j.ab.2010.01.007Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 30 records (90 values) from this paper: proteinase 3 (PR3), human neutrophil elastase (HNE) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.76

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide)	0.3	0.932	0.3	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide)
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2	0.7	0.2876	2.5	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2	0.5	0.3405	1.4	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2	2.7	0.5493	4.9	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2	3	0.2815	10.5	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2	2.8	0.2753	10.1	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2	3.9	0.3381	11.5	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2	2.1	0.6385	3.2	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2	3.9	0.3527	11.1	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2	3.7	0.4129	8.9	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2
human neutrophil elastase (HNE)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2	0.6	0.2144	2.8	pH 7.5, 25 °C	Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide)	5.9	0.0314	188.9	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide)
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2	2.1	0.1731	12.2	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Arg-NH2	2.6	0.0642	41.1	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Arg-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asn-NH2	5.3	0.0251	201.2	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asn-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asp-NH2	4.8	0.0281	170.8	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asp-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gln-NH2	6.4	0.0174	274.9	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gln-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Glu-NH2	3.3	0.0253	138.2	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Glu-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2	3.2	0.1242	25.8	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2	3.1	0.0357	86.7	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2	1.8	0.2763	6.5	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2	2	0.2436	7.2	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Lys-NH2	2.5	0.0729	34.3	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Lys-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2	1.3	1.126	1.1	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2	1.1	0.1823	0.5	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ser-NH2	5.1	0.0278	183.8	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ser-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Thr-NH2	2.8	0.0321	87.3	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Thr-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2	1.3	1.274	0.9	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2	1.6	0.9823	1.6	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2
proteinase 3 (PR3)	Homo sapiens	aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2	4.7	0.3124	15.1	pH 7.5, 25 °C	Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2