EC 3.4.21.76: Myeloblastin
HydrolasesOpen in Browse
CatLog read 32 records for EC 3.4.21.76 from 2 papers, for 1 organism. Names in these papers: proteinase 3 (PR3), human neutrophil elastase (HNE), proteinase 3.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 3 records for EC 3.4.21.76 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.21.76 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region | Homo sapiens | 30 |
| Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates | — | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide) | 0.3 | 0.932 | 0.3 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide) |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2 | 0.7 | 0.2876 | 2.5 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2 | 0.5 | 0.3405 | 1.4 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2 | 2.7 | 0.5493 | 4.9 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2 | 3 | 0.2815 | 10.5 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2 | 2.8 | 0.2753 | 10.1 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2 | 3.9 | 0.3381 | 11.5 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2 | 2.1 | 0.6385 | 3.2 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2 | 3.9 | 0.3527 | 11.1 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2 | 3.7 | 0.4129 | 8.9 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2 |
| human neutrophil elastase (HNE) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2 | 0.6 | 0.2144 | 2.8 | pH 7.5, 25 °C | PMID 20074540 | Open record: human neutrophil elastase (HNE), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2 |
| proteinase 3 | — | O-aminobenzoyl-Gly-Ile-Ala-Pro-Phe-Cys-Asp-Leu-Met-Pro-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 488 | 37 °C | PMID 21599834 | Open record: proteinase 3, O-aminobenzoyl-Gly-Ile-Ala-Pro-Phe-Cys-Asp-Leu-Met-Pro-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| proteinase 3 | — | O-aminobenzoyl-Gly-Ile-Ala-Thr-Phe-Cys-Asp-Leu-Met-Pro-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 2.23 × 10³ | 37 °C | PMID 21599834 | Open record: proteinase 3, O-aminobenzoyl-Gly-Ile-Ala-Thr-Phe-Cys-Asp-Leu-Met-Pro-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide) | 5.9 | 0.0314 | 188.9 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoic acid amide) |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2 | 2.1 | 0.1731 | 12.2 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ala-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Arg-NH2 | 2.6 | 0.0642 | 41.1 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Arg-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asn-NH2 | 5.3 | 0.0251 | 201.2 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asn-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asp-NH2 | 4.8 | 0.0281 | 170.8 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Asp-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gln-NH2 | 6.4 | 0.0174 | 274.9 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gln-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Glu-NH2 | 3.3 | 0.0253 | 138.2 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Glu-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2 | 3.2 | 0.1242 | 25.8 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Gly-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2 | 3.1 | 0.0357 | 86.7 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-His-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2 | 1.8 | 0.2763 | 6.5 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ile-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2 | 2 | 0.2436 | 7.2 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Leu-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Lys-NH2 | 2.5 | 0.0729 | 34.3 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Lys-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2 | 1.3 | 1.126 | 1.1 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Phe-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2 | 1.1 | 0.1823 | 0.5 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Pro-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ser-NH2 | 5.1 | 0.0278 | 183.8 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Ser-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Thr-NH2 | 2.8 | 0.0321 | 87.3 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Thr-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2 | 1.3 | 1.274 | 0.9 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Trp-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2 | 1.6 | 0.9823 | 1.6 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Tyr-NH2 |
| proteinase 3 (PR3) | Homo sapiens | aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2 | 4.7 | 0.3124 | 15.1 | pH 7.5, 25 °C | PMID 20074540 | Open record: proteinase 3 (PR3), aminobenzoyl-Tyr-Tyr-(L-aminobutyryl)-(5-amino-2-nitrobenzoyl)-Val-NH2 |