Values CatLog read from this paper
Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2
PMID 28419689doi:10.1002/pro.3176Open in Browse
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CatLog read 9 records (27 values) from this paper: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) | Homo sapiens | L-phenylalanine | 0.192 | 0.0024 | 80 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS), L-phenylalanine |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) | Homo sapiens | tRNA^{Phe} | 0.192 | 0.0012 | 160 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS), tRNA^{Phe} |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant D289Y | Homo sapiens | tRNA^{Phe} | 0.083 | 0.001 | 83 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant D289Y, tRNA^{Phe} |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant H99D | Homo sapiens | L-phenylalanine | 0.012 | 0.0056 | 2.2 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant H99D, L-phenylalanine |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant P49A | Homo sapiens | tRNA^{Phe} | 0.138 | 0.0011 | 125 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant P49A, tRNA^{Phe} |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant R117G | Homo sapiens | L-phenylalanine | 0.02 | 0.012 | 1.7 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant R117G, L-phenylalanine |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant R383C | Homo sapiens | tRNA^{Phe} | 0.145 | 0.0021 | 68 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant R383C, tRNA^{Phe} |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant R387Q | Homo sapiens | tRNA^{Phe} | 0.18 | 0.0012 | 138 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant R387Q, tRNA^{Phe} |
| human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS)variant T210M | Homo sapiens | tRNA^{Phe} | 0.08 | 3.6 × 10⁻⁴ | 222 | pH 8.5, 37 °C | Open record: human mitochondrial phenylalanyl-tRNA synthetase (HsmtPheRS) variant T210M, tRNA^{Phe} |