Values CatLog read from this paper
Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile
PMID 15003844doi:10.1016/j.molbiopara.2003.12.006Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (23 values) from this paper: orotate phosphoribosyltransferase (pfOPRT) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-Fluoroorotate | 4 | 0.025 | 159 | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-Fluoroorotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphatespectrophotometric (295 nm, orotate); Table 1 | 3.2 | 0.0286 | 113 | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphateorotate at fixed saturating concentration; apparent Km | — | 0.0282 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphateorotate at fixed saturating concentration; apparent Km | — | 0.04 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | Orotatespectrophotometric (295 nm, orotate); Table 1 | 3 | 0.0182 | 164 | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | OrotatePRPP at fixed saturating concentration; apparent Km; Table 2 | — | 0.037 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | OrotatePRPP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0182 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatespectrophotometric (295 nm, orotate); Table 1 | 2.6 | 0.0251 | 102 | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatePP_i at fixed saturating concentration; apparent Km; Table 2 | — | 0.0222 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatePP_i at fixed saturating concentration; apparent Km; Table 2 | — | 0.0333 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphatespectrophotometric (295 nm, orotate); Table 1 | 1.3 | 0.0143 | 94 | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphateOMP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0403 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphateOMP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0227 | — | pH 8, 37 °C | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |