EC 2.4.2.10: orotate phosphoribosyltransferase
TransferasesOpen in Browse
CatLog read 91 records for EC 2.4.2.10 from 4 papers, for 3 organisms. Names in these papers: orotate phosphoribosyltransferase, orotate phosphoribosyltransferase (pfOPRT), orotate phosphoribosyltransferase (OPRTase), orotate phosphoribosyltransferase (MtOPRT).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 39 records for EC 2.4.2.10 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.2.10 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase | Salmonella typhimurium | 60 |
| Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile | Plasmodium falciparum | 13 |
| Structure and function of Salmonella typhimurium orotate phosphoribosyltransferase: protein complementation reveals shared active sites | Salmonella typhimurium | 12 |
| Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase | Mycobacterium tuberculosis | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| orotate phosphoribosyltransferase | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.049 | 690 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | imidodiphosphateanalog 0.25-20 mM | 35 | 0.94 | 38 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, imidodiphosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | imidodiphosphatepyrophosphate-analog series | 35 | 0.9 | 98 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, imidodiphosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | orotic acidforward reaction (OMP synthesis); 75 mM Tris-HCl; 6 mM MgCl2 | 34 | 0.026 | 1.3 × 10³ | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, orotic acid |
| orotate phosphoribosyltransferase | Salmonella typhimurium | orotic acidforward reaction | 32 | 0.028 | 1.14 × 10³ | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, orotic acid |
| orotate phosphoribosyltransferase | Salmonella typhimurium | orotic acid 6-methyl ester | 3.5 | 0.182 | 19 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, orotic acid 6-methyl ester |
| orotate phosphoribosyltransferase | Salmonella typhimurium | orotidine 5'-monophosphate | 18 | 0.005 | 3.6 × 10³ | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | phosphonoacetate | 0.04 | 1.9 | 0.06 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, phosphonoacetate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | phosphonoacetic acid | 0.04 | 1.85 | 0.02 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, phosphonoacetic acid |
| orotate phosphoribosyltransferase | Salmonella typhimurium | pyrophosphate80 mM Tris-HCl; MgCl2 kept 1 mM in excess over PPi | — | 0.033 | 550 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, pyrophosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | pyrophosphatepyrophosphate-analog series | 18 | 0.033 | 1.4 × 10³ | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, pyrophosphate |
| orotate phosphoribosyltransferase | Salmonella typhimurium | uracil | 0.9 | 3.16 | 0.3 | 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase, uracil |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.179 | 64 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | imidodiphosphate | 0.7 | 0.4 | 4 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, imidodiphosphate |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | orotic acid | 12 | 0.072 | 160 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, orotic acid |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | orotidine 5'-monophosphate | 12 | 0.013 | 830 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | phosphonoacetate | 0.09 | 1.8 | 0.1 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, phosphonoacetate |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | pyrophosphate80 mM Tris-HCl; MgCl2 kept 1 mM in excess over PPi | — | 0.958 | 11 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K100A | Salmonella typhimurium | pyrophosphatepyrophosphate-analog series | 11 | 0.96 | 150 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K100A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.285 | 0.2 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | orotic acidforward reaction (OMP synthesis); 75 mM Tris-HCl; 6 mM MgCl2 | 0.05 | 0.042 | 1 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, orotic acid |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | orotic acidforward reaction | 0.06 | 0.043 | 1.3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, orotic acid |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | orotic acid 6-methyl ester | 0.02 | 0.041 | 0.4 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, orotic acid 6-methyl ester |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | orotidine 5'-monophosphate | 0.05 | 0.02 | 2 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K103A | Salmonella typhimurium | pyrophosphate | — | 0.146 | 0.3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.12 | 1 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | imidodiphosphate | 0.05 | 0.4 | 0.3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, imidodiphosphate |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | orotic acid | 0.13 | 0.034 | 4 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, orotic acid |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | orotidine 5'-monophosphate | 0.05 | 0.0034 | 15 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | pyrophosphate80 mM Tris-HCl; MgCl2 kept 1 mM in excess over PPi | — | 0.144 | 0.3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, pyrophosphate |
| orotate phosphoribosyltransferasevariant K103Q | Salmonella typhimurium | pyrophosphatepyrophosphate-analog series | 0.05 | 0.15 | 2.4 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K103Q, pyrophosphate |
| orotate phosphoribosyltransferasevariant K19Q | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.096 | 320 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K19Q, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K19Q | Salmonella typhimurium | orotic acid | 31 | 0.078 | 400 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K19Q, orotic acid |
| orotate phosphoribosyltransferasevariant K19Q | Salmonella typhimurium | orotidine 5'-monophosphate | 12 | 0.018 | 830 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K19Q, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K19Q | Salmonella typhimurium | pyrophosphate | — | 0.05 | 300 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K19Q, pyrophosphate |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.05 | 175 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | orotic acidforward reaction (OMP synthesis); 75 mM Tris-HCl; 6 mM MgCl2 | 8.7 | 0.07 | 125 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, orotic acid |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | orotic acidforward reaction | 10 | 0.067 | 150 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, orotic acid |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | orotidine 5'-monophosphate | 9.6 | 0.019 | 500 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | pyrophosphate | — | 0.074 | 130 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K26A | Salmonella typhimurium | uracil | 0.7 | 3.71 | 0.2 | 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26A, uracil |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.055 | 56 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | imidodiphosphate | 0.12 | 1.1 | 0.3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, imidodiphosphate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | orotic acidforward reaction (OMP synthesis); 75 mM Tris-HCl; 6 mM MgCl2 | 3.1 | 0.065 | 48 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, orotic acid |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | orotic acidforward reaction | 3.3 | 0.07 | 48 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, orotic acid |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | orotic acid 6-methyl ester | 16 | 0.082 | 192 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, orotic acid 6-methyl ester |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | orotidine 5'-monophosphate | 1.3 | 0.037 | 34 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | phosphonoacetate | 0.13 | 3.6 | 0.09 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, phosphonoacetate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | pyrophosphate80 mM Tris-HCl; MgCl2 kept 1 mM in excess over PPi | — | 0.111 | 11 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, pyrophosphate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | pyrophosphatepyrophosphate-analog series | 1.3 | 0.11 | 30 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, pyrophosphate |
| orotate phosphoribosyltransferasevariant K26Q | Salmonella typhimurium | uracil | 0.7 | 1.81 | 0.4 | 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K26Q, uracil |
| orotate phosphoribosyltransferasevariant K73A | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.394 | 0.7 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73A, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K73A | Salmonella typhimurium | orotic acid | 0.3 | 0.029 | 9 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73A, orotic acid |
| orotate phosphoribosyltransferasevariant K73A | Salmonella typhimurium | orotidine 5'-monophosphate | 0.3 | 0.011 | 28 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73A, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K73A | Salmonella typhimurium | pyrophosphate80 mM Tris-HCl; MgCl2 kept 1 mM in excess over PPi | — | 0.182 | 2 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K73A | Salmonella typhimurium | pyrophosphatepyrophosphate-analog series | 0.3 | 0.18 | 2 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73A, pyrophosphate |
| orotate phosphoribosyltransferasevariant K73Q | Salmonella typhimurium | alpha-D-5-phosphoribosyl-1-pyrophosphate | — | 0.576 | 1 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73Q, alpha-D-5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferasevariant K73Q | Salmonella typhimurium | orotic acid | 0.6 | 0.031 | 19 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73Q, orotic acid |
| orotate phosphoribosyltransferasevariant K73Q | Salmonella typhimurium | orotidine 5'-monophosphate | 0.3 | 0.013 | 24 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73Q, orotidine 5'-monophosphate |
| orotate phosphoribosyltransferasevariant K73Q | Salmonella typhimurium | pyrophosphate | — | 0.102 | 3 | pH 8, 30 °C | PMID 7545005 | Open record: orotate phosphoribosyltransferase variant K73Q, pyrophosphate |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | 5-phospho-alpha-D-ribose 1-diphosphateeqn (4) | — | 0.096 | 6 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), 5-phospho-alpha-D-ribose 1-diphosphate |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | 5-phospho-alpha-D-ribose 1-diphosphateeqn (7) | — | 0.09 | 6.6 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), 5-phospho-alpha-D-ribose 1-diphosphate |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | orotic acideqn (4) | 0.61 | 0.01 | 60 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), orotic acid |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | orotic acideqn (7) | 0.6 | 0.0094 | 64 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), orotic acid |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | orotidine 5'-monophosphate | 0.28 | 0.0026 | 100 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (MtOPRT) | Mycobacterium tuberculosis | pyrophosphate | 0.28 | 0.016 | 10 | pH 8, 25 °C | PMID 22075667 | Open record: orotate phosphoribosyltransferase (MtOPRT), pyrophosphate |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + D125N heterodimer (complemented mixture) | Salmonella typhimurium | 5-phospho-alpha-D-ribose 1-diphosphate | — | 0.205 | 13 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + D125N heterodimer (complemented mixture), 5-phospho-alpha-D-ribose 1-diphosphate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + D125N heterodimer (complemented mixture) | Salmonella typhimurium | diphosphate (pyrophosphate) | — | 0.034 | 45 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + D125N heterodimer (complemented mixture), diphosphate (pyrophosphate) | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + D125N heterodimer (complemented mixture) | Salmonella typhimurium | orotate | — | 0.027 | 99 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + D125N heterodimer (complemented mixture), orotate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + D125N heterodimer (complemented mixture) | Salmonella typhimurium | orotidine 5'-monophosphate | — | 0.004 | 380 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + D125N heterodimer (complemented mixture), orotidine 5'-monophosphate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73A heterodimer (complemented mixture) | Salmonella typhimurium | 5-phospho-alpha-D-ribose 1-diphosphate | — | 0.08 | 160 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73A heterodimer (complemented mixture), 5-phospho-alpha-D-ribose 1-diphosphate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73A heterodimer (complemented mixture) | Salmonella typhimurium | diphosphate (pyrophosphate) | — | 0.041 | 200 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73A heterodimer (complemented mixture), diphosphate (pyrophosphate) | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73A heterodimer (complemented mixture) | Salmonella typhimurium | orotate | — | 0.03 | 425 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73A heterodimer (complemented mixture), orotate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73A heterodimer (complemented mixture) | Salmonella typhimurium | orotidine 5'-monophosphate | — | 0.007 | 1.15 × 10³ | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73A heterodimer (complemented mixture), orotidine 5'-monophosphate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73Q heterodimer (complemented mixture) | Salmonella typhimurium | 5-phospho-alpha-D-ribose 1-diphosphate | — | 0.052 | 300 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73Q heterodimer (complemented mixture), 5-phospho-alpha-D-ribose 1-diphosphate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73Q heterodimer (complemented mixture) | Salmonella typhimurium | diphosphate (pyrophosphate) | — | 0.039 | 260 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73Q heterodimer (complemented mixture), diphosphate (pyrophosphate) | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73Q heterodimer (complemented mixture) | Salmonella typhimurium | orotate | — | 0.025 | 600 | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73Q heterodimer (complemented mixture), orotate | |
| orotate phosphoribosyltransferase (OPRTase)variant K103A + K73Q heterodimer (complemented mixture) | Salmonella typhimurium | orotidine 5'-monophosphate | — | 0.005 | 2 × 10³ | PMID 7545006 | Open record: orotate phosphoribosyltransferase (OPRTase) variant K103A + K73Q heterodimer (complemented mixture), orotidine 5'-monophosphate | |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-Fluoroorotate | 4 | 0.025 | 159 | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-Fluoroorotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphatespectrophotometric (295 nm, orotate); Table 1 | 3.2 | 0.0286 | 113 | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphateorotate at fixed saturating concentration; apparent Km | — | 0.0282 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | 5-phosphoribosyl-1-pyrophosphateorotate at fixed saturating concentration; apparent Km | — | 0.04 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), 5-phosphoribosyl-1-pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | Orotatespectrophotometric (295 nm, orotate); Table 1 | 3 | 0.0182 | 164 | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | OrotatePRPP at fixed saturating concentration; apparent Km; Table 2 | — | 0.037 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | OrotatePRPP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0182 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), Orotate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatespectrophotometric (295 nm, orotate); Table 1 | 2.6 | 0.0251 | 102 | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatePP_i at fixed saturating concentration; apparent Km; Table 2 | — | 0.0222 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | orotidine 5'-monophosphatePP_i at fixed saturating concentration; apparent Km; Table 2 | — | 0.0333 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), orotidine 5'-monophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphatespectrophotometric (295 nm, orotate); Table 1 | 1.3 | 0.0143 | 94 | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphateOMP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0403 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |
| orotate phosphoribosyltransferase (pfOPRT) | Plasmodium falciparum | pyrophosphateOMP at fixed saturating concentration; apparent Km; Table 2 | — | 0.0227 | — | pH 8, 37 °C | PMID 15003844 | Open record: orotate phosphoribosyltransferase (pfOPRT), pyrophosphate |