Values CatLog read from this paper

Site-directed mutagenesis of the active site glutamate in human matrilysin: investigation of its role in catalysis

PMID 9398337doi:10.1021/bi972223gOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 5 records (15 values) from this paper: matrilysin (MMP-7) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.24.23

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
matrilysin (MMP-7)	Homo sapiens	5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg	2.7	0.024	120	pH 7.5, 25 °C	Open record: matrilysin (MMP-7), 5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg
matrilysin (MMP-7)variant E198A	Homo sapiens	5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg	5.1 × 10⁻⁴	0.0079	0.065	pH 7.5, 25 °C	Open record: matrilysin (MMP-7) variant E198A, 5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg
matrilysin (MMP-7)variant E198C	Homo sapiens	5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg	0.014	0.018	0.77	pH 7.5, 25 °C	Open record: matrilysin (MMP-7) variant E198C, 5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg
matrilysin (MMP-7)variant E198D	Homo sapiens	5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg	0.61	0.021	29	pH 7.5, 25 °C	Open record: matrilysin (MMP-7) variant E198D, 5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg
matrilysin (MMP-7)variant E198Q	Homo sapiens	5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg	0.0036	0.018	0.2	pH 7.5, 25 °C	Open record: matrilysin (MMP-7) variant E198Q, 5-(dimethylamino)naphthalene-1-sulfonyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg