Values CatLog read from this paper
Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA
PMID 26161441doi:10.1021/id500033mOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: ChsE4-ChsE5, ChsE1-ChsE2, ChsE3 from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| ChsE1-ChsE2 | Mycobacterium tuberculosis | 3-oxo-chol-4-en-24-oyl-CoA | 0.16 | 0.0065 | 24 | pH 8.5, 25 °C | Open record: ChsE1-ChsE2, 3-oxo-chol-4-en-24-oyl-CoA |
| ChsE3 | Mycobacterium tuberculosis | 3-oxo-chol-4-en-24-oyl-CoA | 5 | 0.028 | 180 | pH 8.5, 25 °C | Open record: ChsE3, 3-oxo-chol-4-en-24-oyl-CoA |
| ChsE4-ChsE5 | Mycobacterium tuberculosis | 3-oxo-4-pregnene-20-carboxyl-CoA | 1.5 | 0.0033 | 450 | pH 8.5, 25 °C | Open record: ChsE4-ChsE5, 3-oxo-4-pregnene-20-carboxyl-CoA |
| ChsE4-ChsE5 | Mycobacterium tuberculosis | 3-oxo-chol-4-en-24-oyl-CoA | 0.48 | 0.0026 | 190 | pH 8.5, 25 °C | Open record: ChsE4-ChsE5, 3-oxo-chol-4-en-24-oyl-CoA |
| ChsE4-ChsE5 | Mycobacterium tuberculosis | 3-oxo-cholest-4-en-26-oyl-CoA (1:1 mixture of 25R/25S diastereomers) | 2.7 | 0.0034 | 810 | pH 8.5, 25 °C | Open record: ChsE4-ChsE5, 3-oxo-cholest-4-en-26-oyl-CoA (1:1 mixture of 25R/25S diastereomers) |
| ChsE4-ChsE5 | Mycobacterium tuberculosis | octanoyl-CoA | 0.042 | 0.0041 | 10 | pH 8.5, 25 °C | Open record: ChsE4-ChsE5, octanoyl-CoA |