Values CatLog read from this paper
Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor
PMID 39904336doi:10.1016/j.str.2025.01.008Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 26 records (52 values) from this paper: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 26 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) | Homo sapiens | adenosine 5'-diphosphate | 41 | 0.016 | 2.6 × 10³ calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1), adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) | Homo sapiens | adenosine 5'-triphosphate | 21 | 0.1 | 210 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1), adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) | Homo sapiens | creatine | 21 | 0.6 | 35 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1), creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) | Homo sapiens | phosphocreatine | 39 | 0.17 | 230 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1), phosphocreatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant D321N | Homo sapiens | adenosine 5'-diphosphate | 12 | 0.009 | 1.3 × 10³ calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant D321N, adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant D321N | Homo sapiens | adenosine 5'-triphosphate | 11 | 0.11 | 100 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant D321N, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant D321N | Homo sapiens | creatine | 11 | 2.2 | 5.0 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant D321N, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant D321N | Homo sapiens | phosphocreatine | 12 | 0.09 | 130 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant D321N, phosphocreatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E226A | Homo sapiens | adenosine 5'-triphosphate | 0.0054 | 0.23 | 0.023 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E226A, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E226A | Homo sapiens | creatine | 0.007 | 18 | 3.9 × 10⁻⁴ calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E226A, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227D | Homo sapiens | adenosine 5'-diphosphate | 0.006 | 0.0114 | 0.53 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227D, adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227D | Homo sapiens | adenosine 5'-triphosphate | 0.004 | 0.08 | 0.050 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227D, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227D | Homo sapiens | creatine | 0.005 | 0.6 | 0.0083 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227D, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227D | Homo sapiens | phosphocreatine | 0.006 | 0.139 | 0.043 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227D, phosphocreatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227Q | Homo sapiens | adenosine 5'-diphosphate | 5 × 10⁻⁴ | 0.013 | 0.038 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227Q, adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227Q | Homo sapiens | adenosine 5'-triphosphate | 3 × 10⁻⁴ | 0.12 | 0.0025 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227Q, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227Q | Homo sapiens | creatine | 2.2 × 10⁻⁴ | 0.8 | 2.8 × 10⁻⁴ calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227Q, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant E227Q | Homo sapiens | phosphocreatine | 5 × 10⁻⁴ | 0.19 | 0.0026 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant E227Q, phosphocreatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61A | Homo sapiens | adenosine 5'-diphosphate | 28 | 0.033 | 850 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61A, adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61A | Homo sapiens | adenosine 5'-triphosphate | 6 | 0.3 | 20 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61A, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61A | Homo sapiens | creatine | 11 | 43 | 0.26 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61A, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61A | Homo sapiens | phosphocreatine | 28 | 3 | 9.3 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61A, phosphocreatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61K | Homo sapiens | adenosine 5'-diphosphate | 5 | 0.029 | 170 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61K, adenosine 5'-diphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61K | Homo sapiens | adenosine 5'-triphosphate | 1.3 | 0.4 | 3.2 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61K, adenosine 5'-triphosphate |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61K | Homo sapiens | creatine | 2 | 30 | 0.067 calc. | pH 8.5 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61K, creatine |
| ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1)variant H61K | Homo sapiens | phosphocreatine | 5 | 3.4 | 1.5 calc. | pH 7 | Open record: ubiquitous mitochondrial creatine kinase (uMtCK, MtCK1) variant H61K, phosphocreatine |