CatLogenzyme kinetics catalog

Values CatLog read from this paper

Fidelity, mismatch extension, and proofreading activity of the Plasmodium falciparum apicoplast DNA polymerase

PMID 24147857doi:10.1021/bi400708mOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 29 records (55 values) from this paper: apicoplast DNA polymerase (apPOL, 3'-5' exonuclease), apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient) from Plasmodium falciparum.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.7.7, EC 2.7.7.102, EC 5.6.2.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumA:A primer:template DNA (3'-terminal primer base : template base)0.14——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumA:C primer:template DNA (3'-terminal primer base : template base)0.36——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumA:G primer:template DNA (3'-terminal primer base : template base)0.15——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumA:T primer:template DNA (3'-terminal primer base : template base)0.07——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumC:A primer:template DNA (3'-terminal primer base : template base)0.26——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumC:C primer:template DNA (3'-terminal primer base : template base)0.41——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumC:G primer:template DNA (3'-terminal primer base : template base)0.03——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumC:T primer:template DNA (3'-terminal primer base : template base)0.28——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumG:A primer:template DNA (3'-terminal primer base : template base)0.27——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumG:C primer:template DNA (3'-terminal primer base : template base)0.06——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumG:G primer:template DNA (3'-terminal primer base : template base)0.37——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumG:T primer:template DNA (3'-terminal primer base : template base)0.32——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumT:A primer:template DNA (3'-terminal primer base : template base)0.06——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumT:C primer:template DNA (3'-terminal primer base : template base)0.37——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumT:G primer:template DNA (3'-terminal primer base : template base)0.3——Open
apicoplast DNA polymerase (apPOL, 3'-5' exonuclease)Plasmodium falciparumT:T primer:template DNA (3'-terminal primer base : template base)0.29——Open
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyadenosine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00260.1480.017625 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyadenosine 5'-triphosphate8 nM apPOLexo⁻0.340.001720025 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyadenosine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00330.9030.0036525 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyadenosine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00610.2410.025325 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxycytidine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00130.3450.0037725 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxycytidine 5'-triphosphate8 nM apPOLexo⁻0.240.00733325 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyguanosine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00120.2620.0045825 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyguanosine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00340.0730.046625 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyguanosine 5'-triphosphate80 or 200 nM apPOLexo⁻6 × 10⁻⁴0.5620.0010725 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxyguanosine 5'-triphosphate8 nM apPOLexo⁻0.337 × 10⁻⁴47025 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxythymidine 5'-triphosphate8 nM apPOLexo⁻0.330.00516525 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxythymidine 5'-triphosphate80 or 200 nM apPOLexo⁻0.00180.1420.012725 °COpen
apicoplast DNA polymerase (apPOLexo-, exonuclease-deficient)variant D1470N/E1472Q (apPOLexo-)Plasmodium falciparum2'-deoxythymidine 5'-triphosphate80 or 200 nM apPOLexo⁻8 × 10⁻⁴0.1590.0050325 °COpen