Values CatLog read from this paper
Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases
PMID 15866534doi:10.1016/j.ab.2005.03.003Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 15 records (15 values) from this paper: UDP-glucuronosyltransferase UGT1A9, UDP-glucuronosyltransferase UGT1A3, UDP-glucuronosyltransferase UGT2B15 and 3 more from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| UDP-glucuronosyltransferase UGT1A1 | Homo sapiens | 7-hydroxy-4-methylcoumarin | — | 0.115 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A1, 7-hydroxy-4-methylcoumarin |
| UDP-glucuronosyltransferase UGT1A1 | Homo sapiens | 7-hydroxycoumarin | — | 0.294 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A1, 7-hydroxycoumarin |
| UDP-glucuronosyltransferase UGT1A3 | Homo sapiens | 7-hydroxy-4-methylcoumarin | — | 0.335 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A3, 7-hydroxy-4-methylcoumarin |
| UDP-glucuronosyltransferase UGT1A3 | Homo sapiens | 8-hydroxyquinoline | — | 0.494 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A3, 8-hydroxyquinoline |
| UDP-glucuronosyltransferase UGT1A3 | Homo sapiens | Entacapone | — | 0.259 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A3, Entacapone |
| UDP-glucuronosyltransferase UGT1A6 | Homo sapiens | 7-hydroxy-4-methylcoumarin | — | 0.157 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A6, 7-hydroxy-4-methylcoumarin |
| UDP-glucuronosyltransferase UGT1A6 | Homo sapiens | 8-hydroxyquinoline | — | 0.0065 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A6, 8-hydroxyquinoline |
| UDP-glucuronosyltransferase UGT1A9 | Homo sapiens | 7-hydroxy-4-methylcoumarin | — | 0.018 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A9, 7-hydroxy-4-methylcoumarin |
| UDP-glucuronosyltransferase UGT1A9 | Homo sapiens | 7-hydroxycoumarin | — | 0.111 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A9, 7-hydroxycoumarin |
| UDP-glucuronosyltransferase UGT1A9 | Homo sapiens | 8-hydroxyquinoline | — | 4.8 × 10⁻⁴ | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A9, 8-hydroxyquinoline |
| UDP-glucuronosyltransferase UGT1A9 | Homo sapiens | Entacapone | — | 0.021 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT1A9, Entacapone |
| UDP-glucuronosyltransferase UGT2B15 | Homo sapiens | 7-hydroxy-4-methylcoumarin | — | 0.149 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT2B15, 7-hydroxy-4-methylcoumarin |
| UDP-glucuronosyltransferase UGT2B15 | Homo sapiens | 7-hydroxycoumarin | — | 0.339 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT2B15, 7-hydroxycoumarin |
| UDP-glucuronosyltransferase UGT2B15 | Homo sapiens | 8-hydroxyquinoline | — | 0.016 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT2B15, 8-hydroxyquinoline |
| UDP-glucuronosyltransferase UGT2B7 | Homo sapiens | 8-hydroxyquinoline | — | 0.301 | — | pH 7.4, 37 °C | Open record: UDP-glucuronosyltransferase UGT2B7, 8-hydroxyquinoline |