CatLogenzyme kinetics catalog

Values CatLog read from this paper

Substrate specificity of human cathepsin D using internally quenched fluorescent peptides derived from reactive site loop of kallistatin

PMID 11341921doi:10.1016/s0167-4838(00)00209-0Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 55 records (165 values) from this paper: cathepsin D from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.23.5

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ala-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.64.5 × 10⁻⁴5778pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Asn-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine5.857.6 × 10⁻⁴7697pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Gln-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.288.2 × 10⁻⁴2781pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Glu-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine6.183.1 × 10⁻⁴19,936pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Ala-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine16.252.7 × 10⁻⁴60,185pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Asn-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine8.458.1 × 10⁻⁴10,432pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Gln-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine12.354.3 × 10⁻⁴28,721pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Glu-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine7.481.7 × 10⁻⁴4.4 × 10⁴pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Ile-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.475 × 10⁻⁵9.4 × 10³pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Leu-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine7.81.9 × 10⁻⁴41,053pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Leu-Leu-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.982.8 × 10⁻⁴3.5 × 10³pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Leu-Met-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.281.7 × 10⁻⁴13,382pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Leu-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine7.154.1 × 10⁻⁴16,646pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Met-Leu-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.31.6 × 10⁻⁴8125pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Met-Met-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.37.6 × 10⁻⁴1711pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Met-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine13.980.0010213,705pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Met-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.33.1 × 10⁻⁴4194pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ala-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine3.92.8 × 10⁻⁴13,929pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Arg-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.953.4 × 10⁻⁴5735pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Asn-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.989 × 10⁻⁵10,889pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Gln-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.39 × 10⁻⁵14,444pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Glu-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.283.4 × 10⁻⁴6706pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ile-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.652.1 × 10⁻⁴3095pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Leu-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.631 × 10⁻⁴1.63 × 10⁴pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Lys-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.653 × 10⁻⁴2167pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-N-[2,4-dinitrophenyl]ethylenediamineTable 16.344.6 × 10⁻⁴13,826pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-N-[2,4-dinitrophenyl]ethylenediamineTable 66.184.6 × 10⁻⁴13,435pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-Thr-Asn-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine17.818 × 10⁻⁴22,262pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-Thr-Asn-Arg-His-Ile-Leu-Arg-Phe-Asn-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.448 × 10⁻⁵3.05 × 10⁴pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine4.880.00124067pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Asn-Gln-N-[2,4-dinitrophenyl]ethylenediamine3.255 × 10⁻⁴6.5 × 10³pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Gln-Gln-N-[2,4-dinitrophenyl]ethylenediamine4.886.6 × 10⁻⁴7394pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Glu-Gln-N-[2,4-dinitrophenyl]ethylenediamine3.586.6 × 10⁻⁴5424pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ile-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.637 × 10⁻⁵23,286pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Leu-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.61.1 × 10⁻⁴23,636pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Lys-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.35.5 × 10⁻⁴2364pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Pro-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.35.7 × 10⁻⁴2281pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ser-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.982.1 × 10⁻⁴4667pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Thr-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.64.3 × 10⁻⁴6046pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Val-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.281 × 10⁻⁴2.28 × 10⁴pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Thr-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.632.3 × 10⁻⁴7087pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Val-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.637 × 10⁻⁵23,286pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Lys-Tyr-Tyr-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.69 × 10⁻⁵28,889pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Met-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.473.7 × 10⁻⁴6676pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Phe-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.887 × 10⁻⁵12,571pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Pro-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.0818.5 × 10⁻⁴95pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Ser-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine8.783.2 × 10⁻⁴27,438pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Thr-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine5.538.6 × 10⁻⁴6.43 × 10³pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ile-Val-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.841.7 × 10⁻⁴4941pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Leu-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine16.585.4 × 10⁻⁴42,513pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Lys-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine1.31.6 × 10⁻⁴8125pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Pro-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine2.935.2 × 10⁻⁴5635pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Ser-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine0.659.6 × 10⁻⁴677pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Thr-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine3.587 × 10⁻⁴5114pH 4, 37 °COpen
cathepsin DHomo sapiensortho-aminobenzoyl-Ala-Val-Lys-Phe-Phe-Ser-Arg-Gln-N-[2,4-dinitrophenyl]ethylenediamine8.783.9 × 10⁻⁴28,323pH 4, 37 °COpen