CatLogenzyme kinetics catalog

Values CatLog read from this paper

Production and Characterization of Recombinant Wild Type Uricase from Indonesian Coelacanth (L. menadoensis) and Improvement of Its Thermostability by In Silico Rational Design and Disulphide…

PMID 30871218doi:10.3390/ijms20061269Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 6 records (18 values) from this paper: uricase (urate oxidase, LM-UOX) from Latimeria menadoensis.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.7.3.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
uricase (urate oxidase, LM-UOX)Latimeria menadoensisuric acid29.890.018431.62 × 10³pH 8, 30 °COpen
uricase (urate oxidase, LM-UOX)variant A132C/A225CLatimeria menadoensisuric acid58.190.039191.49 × 10³pH 8, 30 °COpen
uricase (urate oxidase, LM-UOX)variant D288CLatimeria menadoensisuric acid65.070.1897340pH 8, 30 °COpen
uricase (urate oxidase, LM-UOX)variant I27C/N289CLatimeria menadoensisuric acid32.580.03539920pH 8, 30 °COpen
uricase (urate oxidase, LM-UOX)variant N289CLatimeria menadoensisuric acid34.060.030461.12 × 10³pH 8, 30 °COpen
uricase (urate oxidase, LM-UOX)variant S136CLatimeria menadoensisuric acid22.490.015281.47 × 10³pH 8, 30 °COpen