Values CatLog read from this paper
Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I
PMID 15733845doi:10.1016/j.febslet.2005.01.035Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: tripeptidyl-peptidase I (TPP I, CLN2 protein) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| tripeptidyl-peptidase I (TPP I, CLN2 protein) | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 41.66 | 0.098 | 425.1 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein), Ala-Ala-Phe-7-amino-4-methylcoumarin |
| tripeptidyl-peptidase I (TPP I, CLN2 protein)variant D276A | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 9.36 | 0.105 | 89.14 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein) variant D276A, Ala-Ala-Phe-7-amino-4-methylcoumarin |
| tripeptidyl-peptidase I (TPP I, CLN2 protein)variant D327A | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 4.22 | 0.164 | 25.73 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein) variant D327A, Ala-Ala-Phe-7-amino-4-methylcoumarin |
| tripeptidyl-peptidase I (TPP I, CLN2 protein)variant D360A | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 1.52 | 0.111 | 12.69 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein) variant D360A, Ala-Ala-Phe-7-amino-4-methylcoumarin |
| tripeptidyl-peptidase I (TPP I, CLN2 protein)variant E272A | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 1.54 | 0.118 | 13.05 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein) variant E272A, Ala-Ala-Phe-7-amino-4-methylcoumarin |
| tripeptidyl-peptidase I (TPP I, CLN2 protein)variant S475L | Homo sapiens | Ala-Ala-Phe-7-amino-4-methylcoumarin | 0.12 | 0.076 | 1.58 | pH 5, 37 °C | Open record: tripeptidyl-peptidase I (TPP I, CLN2 protein) variant S475L, Ala-Ala-Phe-7-amino-4-methylcoumarin |