Values CatLog read from this paper
Binding energy and specificity in the catalytic mechanism of yeast aldose reductases
PMID 10548539doi:10.1042/bj3440101Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 60 records (151 values) from this paper: aldose reductase II (NAD(P)H-dependent), aldose reductase I (NADPH-dependent), NADPH-dependent aldose reductase and 1 more from Candida intermedia, Cryptococcus flavus, Candida tenuis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5,6-dideoxy-5,6-difluoro-D-glucofuranose | 22 | 1.5 | 14.7 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5,6-dideoxy-5,6-difluoro-D-glucofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5,6-dideoxy-5-fluoro-D-glucofuranose | 21 | 3 | 7 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5,6-dideoxy-5-fluoro-D-glucofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5,6-dideoxy-6-fluoro-D-xylohexofuranose | 34 | 10.4 | 3.269 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5,6-dideoxy-6-fluoro-D-xylohexofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5,6-dideoxy-D-xylohexofuranose | 27 | 2.2 | 12.27 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5,6-dideoxy-D-xylohexofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5-azido-5-deoxy-D-xylofuranose | — | — | 1.12 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5-azido-5-deoxy-D-xylofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5-deoxy-D-xylofuranose | 18.1 | 1 | 18.1 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5-deoxy-D-xylofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 5-fluoro-5-deoxy-D-xylofuranose | 20 | 1.6 | 12.5 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 5-fluoro-5-deoxy-D-xylofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose | 19 | 1.3 | 14.62 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | 6-azido-5,6-dideoxy-D-xylohexofuranose | — | — | 0.202 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), 6-azido-5,6-dideoxy-D-xylohexofuranose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | cyclohexanecarboxaldehyde | 13.1 | 0.32 | 40.94 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), cyclohexanecarboxaldehyde |
| aldose reductase I (NADPH-dependent) | Candida intermedia | D-galactose | 9.4 | 303 | 0.031 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), D-galactose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | D-glucose | 5.1 | 264 | 0.0193 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), D-glucose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | D-xylose | 14.6 | 82 | 0.178 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), D-xylose |
| aldose reductase I (NADPH-dependent) | Candida intermedia | heptanal | 22 | 2.5 | 8.8 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), heptanal |
| aldose reductase I (NADPH-dependent) | Candida intermedia | NADPH | — | — | 400 | pH 7, 25 °C | Open record: aldose reductase I (NADPH-dependent), NADPH |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5,6-dideoxy-5,6-difluoro-D-glucofuranose | 12 | 4.5 | 2.67 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5,6-dideoxy-5,6-difluoro-D-glucofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5,6-dideoxy-5-fluoro-D-glucofuranose | 13 | 8.9 | 1.461 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5,6-dideoxy-5-fluoro-D-glucofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5,6-dideoxy-6-fluoro-D-xylohexofuranose | 21 | 14.7 | 1.428 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5,6-dideoxy-6-fluoro-D-xylohexofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5,6-dideoxy-D-xylohexofuranose | 14 | 1.7 | 8.235 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5,6-dideoxy-D-xylohexofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5-azido-5-deoxy-D-xylofuranose | — | — | 0.346 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5-azido-5-deoxy-D-xylofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5-deoxy-D-xylofuranose | 13.5 | 1.3 | 10.38 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5-deoxy-D-xylofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 5-fluoro-5-deoxy-D-xylofuranose | 15.5 | 2.4 | 6.458 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 5-fluoro-5-deoxy-D-xylofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose | 14 | 2.5 | 5.6 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | 6-azido-5,6-dideoxy-D-xylohexofuranose | — | — | 0.148 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), 6-azido-5,6-dideoxy-D-xylohexofuranose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | cyclohexanecarboxaldehyde | — | — | 1.081 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), cyclohexanecarboxaldehyde |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | D-galactose | 5.9 | 74 | 0.08 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), D-galactose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | D-glucose | — | — | 0.0027 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), D-glucose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | D-xylose | 10.5 | 50 | 0.21 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), D-xylose |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | heptanal | 4.6 | 4.7 | 0.979 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), heptanal |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | NADH | — | — | 297 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), NADH |
| aldose reductase II (NAD(P)H-dependent) | Candida intermedia | NADPH | — | — | 548 | pH 7, 25 °C | Open record: aldose reductase II (NAD(P)H-dependent), NADPH |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5,6-dideoxy-5,6-difluoro-D-glucofuranose | 18 | 1.4 | 12.86 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5,6-dideoxy-5,6-difluoro-D-glucofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5,6-dideoxy-5-fluoro-D-glucofuranose | 18 | 1.2 | 15 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5,6-dideoxy-5-fluoro-D-glucofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5,6-dideoxy-6-fluoro-D-xylohexofuranose | 18 | 2.6 | 6.923 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5,6-dideoxy-6-fluoro-D-xylohexofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5,6-dideoxy-D-xylohexofuranose | 18 | 0.5 | 36 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5,6-dideoxy-D-xylohexofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5-azido-5-deoxy-D-xylofuranose | — | — | 1.69 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5-azido-5-deoxy-D-xylofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5-deoxy-D-xylofuranose | 18 | 0.9 | 20 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5-deoxy-D-xylofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 5-fluoro-5-deoxy-D-xylofuranose | 19 | 0.6 | 31.7 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 5-fluoro-5-deoxy-D-xylofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose | 16 | 0.7 | 22.86 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | 6-azido-5,6-dideoxy-D-xylohexofuranose | — | — | 0.324 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, 6-azido-5,6-dideoxy-D-xylohexofuranose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | cyclohexanecarboxaldehyde | 20 | 0.28 | 7.143 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, cyclohexanecarboxaldehyde |
| NAD(P)H-dependent aldose reductase | Candida tenuis | D-galactose | — | 228 | 0.053 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, D-galactose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | D-glucose | — | — | 0.021 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, D-glucose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | D-xylose | 14 | 64 | 0.219 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, D-xylose |
| NAD(P)H-dependent aldose reductase | Candida tenuis | heptanal | 21 | 5.4 | 3.888 | pH 7, 25 °C | Open record: NAD(P)H-dependent aldose reductase, heptanal |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5,6-dideoxy-5,6-difluoro-D-glucofuranose | 19 | 4.4 | 4.318 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5,6-dideoxy-5,6-difluoro-D-glucofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5,6-dideoxy-5-fluoro-D-glucofuranose | 14 | 0.4 | 35 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5,6-dideoxy-5-fluoro-D-glucofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5,6-dideoxy-6-fluoro-D-xylohexofuranose | 14 | 1 | 14 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5,6-dideoxy-6-fluoro-D-xylohexofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5,6-dideoxy-D-xylohexofuranose | 15 | 0.9 | 16.7 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5,6-dideoxy-D-xylohexofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5-azido-5-deoxy-D-xylofuranose | 11.2 | 4 | 2.8 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5-azido-5-deoxy-D-xylofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5-deoxy-D-xylofuranose | 12.5 | 0.7 | 17.86 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5-deoxy-D-xylofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 5-fluoro-5-deoxy-D-xylofuranose | 15.6 | 1 | 15.6 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 5-fluoro-5-deoxy-D-xylofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose | 14 | 0.6 | 23.3 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | 6-azido-5,6-dideoxy-D-xylohexofuranose | — | — | 0.9 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, 6-azido-5,6-dideoxy-D-xylohexofuranose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | cyclohexanecarboxaldehyde | 6.3 | 9.8 | 0.643 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, cyclohexanecarboxaldehyde |
| NADPH-dependent aldose reductase | Cryptococcus flavus | D-galactose | 5.9 | 51 | 0.116 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, D-galactose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | D-glucose | 3.4 | 100 | 0.034 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, D-glucose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | D-xylose | 8.8 | 27 | 0.326 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, D-xylose |
| NADPH-dependent aldose reductase | Cryptococcus flavus | heptanal | 9.2 | 0.6 | 15.3 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, heptanal |
| NADPH-dependent aldose reductase | Cryptococcus flavus | NADPH | — | — | 808 | pH 7, 25 °C | Open record: NADPH-dependent aldose reductase, NADPH |