CatLogenzyme kinetics catalog

Values CatLog read from this paper

Site-directed mutagenesis studies on the determinants of sugar specificity and cooperative behavior of human beta-cell glucokinase

PMID 7961659doi:10.1016/s0021-9258(18)47007-xOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 39 records (68 values) from this paper: beta-cell glucokinase (hexokinase IV) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 17 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.7.1.2

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
beta-cell glucokinase (hexokinase IV)Homo sapiens2-deoxy-D-glucoseTable II56.7——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiens2-deoxy-D-glucoseTable IV56.4——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensadenosine 5'-triphosphate—0.63—30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-fructoseTable II117.4——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-fructoseTable IV116.92400.49 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-glucosamine20610.33 calc.pH 9, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-glucoseTable I66.7——30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-glucoseTable IV66.4——30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-mannoseTable II56——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)Homo sapiensD-mannoseTable IV56.44.413 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant E256AHomo sapiens2-deoxy-D-glucose1.54600.0033 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant E256AHomo sapiensadenosine 5'-triphosphate—0.58—30 °COpen
beta-cell glucokinase (hexokinase IV)variant E256AHomo sapiensD-glucose1.84760.003730 °COpen
beta-cell glucokinase (hexokinase IV)variant E290AHomo sapiens2-deoxy-D-glucose4.64700.0098 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant E290AHomo sapiensadenosine 5'-triphosphate—1.26—30 °COpen
beta-cell glucokinase (hexokinase IV)variant E290AHomo sapiensD-fructose2.42.9 × 10³8.3 × 10⁻⁴ calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant E290AHomo sapiensD-glucose12.51760.07130 °COpen
beta-cell glucokinase (hexokinase IV)variant E290AHomo sapiensD-mannose7.93500.023 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant K56AHomo sapiens2-deoxy-D-glucose62.8——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant K56AHomo sapiensadenosine 5'-triphosphate—0.65—30 °COpen
beta-cell glucokinase (hexokinase IV)variant K56AHomo sapiensD-fructose3513.5 × 10³0.10 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant K56AHomo sapiensD-glucose73.9——30 °COpen
beta-cell glucokinase (hexokinase IV)variant K56AHomo sapiensD-mannose62.815.74.00 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204AHomo sapiens2-deoxy-D-glucose1.71.4 × 10³0.0012 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204AHomo sapiensD-glucosamine0.0771206.4 × 10⁻⁴ calc.pH 9, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204AHomo sapiensD-glucose5.61520.03730 °COpen
beta-cell glucokinase (hexokinase IV)variant N204AHomo sapiensD-mannose2.8——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204DHomo sapiens2-deoxy-D-glucose2.152.1 × 10³0.0010 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204DHomo sapiensD-glucosamine0.077600.0013 calc.pH 9, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204DHomo sapiensD-glucose7.58400.008930 °COpen
beta-cell glucokinase (hexokinase IV)variant N204QHomo sapiens2-deoxy-D-glucose0.551.7 × 10³3.2 × 10⁻⁴ calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204QHomo sapiensD-glucosamine—100—pH 9, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204QHomo sapiensD-glucose5570.08730 °COpen
beta-cell glucokinase (hexokinase IV)variant N204QHomo sapiensD-mannose54000.013 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204SHomo sapiens2-deoxy-D-glucose15.4——pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204SHomo sapiensD-fructose55.81.1 × 10³0.051 calc.pH 7.5, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204SHomo sapiensD-glucosamine8.81600.055 calc.pH 9, 30 °COpen
beta-cell glucokinase (hexokinase IV)variant N204SHomo sapiensD-glucose31.77.74.130 °COpen
beta-cell glucokinase (hexokinase IV)variant N204SHomo sapiensD-mannose21——pH 7.5, 30 °COpen