Values CatLog read from this paper
Serendipitous discovery of α-hydroxyalkyl esters as β-lactamase substrates
PMID 21087009doi:10.1021/bi101071rOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (34 values) from this paper: P99 β-lactamase, TEM-2 β-lactamase from Enterobacter cloacae, Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| P99 β-lactamase | Enterobacter cloacae | 3-carboxyphenyl D-2-hydroxy-3-phenylpropanoate | 6.9 | 0.172 | 39 | pH 7.5, 25 °C | Open record: P99 β-lactamase, 3-carboxyphenyl D-2-hydroxy-3-phenylpropanoate |
| P99 β-lactamase | Enterobacter cloacae | compound 12 | 3.5 | 0.46 | 7.5 | pH 7.5, 25 °C | Open record: P99 β-lactamase, compound 12 |
| P99 β-lactamase | Enterobacter cloacae | compound 13 | 1.5 | 0.02 | 55 | pH 7.5, 25 °C | Open record: P99 β-lactamase, compound 13 |
| P99 β-lactamase | Enterobacter cloacae | compound 16 | 7.4 | 0.48 | 15 | pH 7.5, 25 °C | Open record: P99 β-lactamase, compound 16 |
| P99 β-lactamase | Enterobacter cloacae | compound 19 | 10.9 | 0.32 | 34 | pH 7.5, 25 °C | Open record: P99 β-lactamase, compound 19 |
| P99 β-lactamase | Enterobacter cloacae | N-(benzyloxycarbonyl)-N-methyl-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine | 21 | 0.66 | 32 | pH 7.5, 25 °C | Open record: P99 β-lactamase, N-(benzyloxycarbonyl)-N-methyl-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine |
| P99 β-lactamase | Enterobacter cloacae | N-(benzyloxycarbonyl)-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine | 8.7 | 0.071 | 120 | pH 7.5, 25 °C | Open record: P99 β-lactamase, N-(benzyloxycarbonyl)-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine |
| P99 β-lactamase | Enterobacter cloacae | N-(benzyloxycarbonyl)-O-(D-2-hydroxypropanoyl)hydroxylamine | 1.5 | 0.52 | 2.8 | pH 7.5, 25 °C | Open record: P99 β-lactamase, N-(benzyloxycarbonyl)-O-(D-2-hydroxypropanoyl)hydroxylamine |
| P99 β-lactamase | Enterobacter cloacae | N-(benzyloxycarbonyl)-O-(D-2-methoxypropanoyl)hydroxylamine | — | — | 0.046 | pH 7.5, 25 °C | Open record: P99 β-lactamase, N-(benzyloxycarbonyl)-O-(D-2-methoxypropanoyl)hydroxylamine |
| P99 β-lactamase | Enterobacter cloacae | N-(benzyloxycarbonyl)-O-(L-2-hydroxy-3-phenylpropanoyl)hydroxylamine | 5.9 | 0.34 | 17.4 | pH 7.5, 25 °C | Open record: P99 β-lactamase, N-(benzyloxycarbonyl)-O-(L-2-hydroxy-3-phenylpropanoyl)hydroxylamine |
| P99 β-lactamase | Enterobacter cloacae | phenyl D-2-hydroxy-3-phenylpropanoate | 10.4 | 1.01 | 10 | pH 7.5, 25 °C | Open record: P99 β-lactamase, phenyl D-2-hydroxy-3-phenylpropanoate |
| TEM-2 β-lactamase | Escherichia coli | 3-carboxyphenyl D-2-hydroxy-3-phenylpropanoate | — | — | 0.46 | pH 7.5, 25 °C | Open record: TEM-2 β-lactamase, 3-carboxyphenyl D-2-hydroxy-3-phenylpropanoate |
| TEM-2 β-lactamase | Escherichia coli | N-(benzyloxycarbonyl)-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine | — | — | 2.4 | pH 7.5, 25 °C | Open record: TEM-2 β-lactamase, N-(benzyloxycarbonyl)-O-(D-2-hydroxy-3-phenylpropanoyl)hydroxylamine |
| TEM-2 β-lactamase | Escherichia coli | N-(benzyloxycarbonyl)-O-(L-2-hydroxy-3-phenylpropanoyl)hydroxylamine | — | — | 0.54 | pH 7.5, 25 °C | Open record: TEM-2 β-lactamase, N-(benzyloxycarbonyl)-O-(L-2-hydroxy-3-phenylpropanoyl)hydroxylamine |