Values CatLog read from this paper

Structure and mechanism of human diacylglycerol O-acyltransferase 1

PMID 32433610doi:10.1038/s41586-020-2280-2Open in Browse

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CatLog read 13 records (13 values) from this paper: diacylglycerol O-acyltransferase-1 (hDGAT1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.3.1.20

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoctodecyl-CoA—0.0105—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), octodecyl-CoA
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoleoyl coenzyme AHis6 tag removed by TEV; dimeric form—0.0146—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoleoyl coenzyme AHis6 tag removed by TEV; dimeric form; approximate kcat1——pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoleoyl coenzyme AHis6 tag removed by TEV; tetrameric form—0.0166—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoleoyl coenzyme AHis6 tag removed by TEV; tetrameric form; approximate kcat1——pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensoleoyl coenzyme Ain crude insect-cell (High Five) membranes; not purified—0.0159—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapienspalmitoleoyl-CoA—0.0062—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), palmitoleoyl-CoA
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapienspalmitoyl-CoA—0.0064—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), palmitoyl-CoA
diacylglycerol O-acyltransferase-1 (hDGAT1)Homo sapiensstearoyl-CoA—0.0086—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1), stearoyl-CoA
diacylglycerol O-acyltransferase-1 (hDGAT1)variant ΔN65Homo sapiensoleoyl coenzyme A—0.0139—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1) variant ΔN65, oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)variant ΔN70Homo sapiensoleoyl coenzyme A—0.0244—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1) variant ΔN70, oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)variant ΔN75Homo sapiensoleoyl coenzyme A—0.0282—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1) variant ΔN75, oleoyl coenzyme A
diacylglycerol O-acyltransferase-1 (hDGAT1)variant ΔN80Homo sapiensoleoyl coenzyme A—0.0286—pH 7.5, 37 °COpen record: diacylglycerol O-acyltransferase-1 (hDGAT1) variant ΔN80, oleoyl coenzyme A