Values CatLog read from this paper
Computational Design of CYP102A1 Variants for Biosynthesis of a Next-Generation Antiplatelet Drug DT-678
PMID 41791881doi:10.1021/acssynbio.5c00768Open in Browse
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CatLog read 5 records (15 values) from this paper: CYP102A1.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP102A1variant A82F | — | 2-oxo-clopidogrel | 0.083 | 0.1213 | 0.67 | pH 7.4, 25 °C | Open record: CYP102A1 variant A82F, 2-oxo-clopidogrel |
| CYP102A1variant A82F/F87V/L188Q (TM) | — | 2-oxo-clopidogrel | 0.293 | 0.174 | 1.7 | pH 7.4, 25 °C | Open record: CYP102A1 variant A82F/F87V/L188Q (TM), 2-oxo-clopidogrel |
| CYP102A1variant S72G/A82F/F87I (UD6) | — | 2-oxo-clopidogrel | 0.56 | 0.2419 | 2.3 | pH 7.4, 25 °C | Open record: CYP102A1 variant S72G/A82F/F87I (UD6), 2-oxo-clopidogrel |
| CYP102A1variant S72G/A82F/F87I/L188Q (UD5) | — | 2-oxo-clopidogrel | 0.453 | 0.1922 | 2.3 | pH 7.4, 25 °C | Open record: CYP102A1 variant S72G/A82F/F87I/L188Q (UD5), 2-oxo-clopidogrel |
| CYP102A1variant S72G/A82F/F87V/L188Q (UD4) | — | 2-oxo-clopidogrel | 0.345 | 0.1879 | 1.8 | pH 7.4, 25 °C | Open record: CYP102A1 variant S72G/A82F/F87V/L188Q (UD4), 2-oxo-clopidogrel |