Values CatLog read from this paper
Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity
PMID 20299452doi:10.1074/jbc.m109.039024Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (21 values) from this paper: choline kinase α2 (ChoKα2), choline kinase β (ChoKβ), choline kinase α1 (ChoKα1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| choline kinase α1 (ChoKα1) | Homo sapiens | adenosine 5'-triphosphate | — | 0.76 | — | Open record: choline kinase α1 (ChoKα1), adenosine 5'-triphosphate | |
| choline kinase α1 (ChoKα1) | Homo sapiens | choline | 76.8 | 0.18 | 430 calc. | Open record: choline kinase α1 (ChoKα1), choline | |
| choline kinase α2 (ChoKα2) | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | Open record: choline kinase α2 (ChoKα2), adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2) | Homo sapiens | choline | 47.3 | 0.086 | 550 calc. | Open record: choline kinase α2 (ChoKα2), choline | |
| choline kinase α2 (ChoKα2)variant L401A | Homo sapiens | adenosine 5'-triphosphate | — | 0.55 | — | Open record: choline kinase α2 (ChoKα2) variant L401A, adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2)variant L401A | Homo sapiens | choline | 49.5 | 0.107 | 463 calc. | Open record: choline kinase α2 (ChoKα2) variant L401A, choline | |
| choline kinase α2 (ChoKα2)variant L401F | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | Open record: choline kinase α2 (ChoKα2) variant L401F, adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2)variant L401F | Homo sapiens | choline | 14 | 0.021 | 670 calc. | Open record: choline kinase α2 (ChoKα2) variant L401F, choline | |
| choline kinase β (ChoKβ) | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | Open record: choline kinase β (ChoKβ), adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ) | Homo sapiens | choline | 2.92 | 0.033 | 88 calc. | Open record: choline kinase β (ChoKβ), choline | |
| choline kinase β (ChoKβ)variant F352A | Homo sapiens | adenosine 5'-triphosphate | — | 0.65 | — | Open record: choline kinase β (ChoKβ) variant F352A, adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ)variant F352A | Homo sapiens | choline | 9.5 | 0.102 | 93 calc. | Open record: choline kinase β (ChoKβ) variant F352A, choline | |
| choline kinase β (ChoKβ)variant F352L | Homo sapiens | adenosine 5'-triphosphate | — | 0.7 | — | Open record: choline kinase β (ChoKβ) variant F352L, adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ)variant F352L | Homo sapiens | choline | 4.58 | 0.041 | 110 calc. | Open record: choline kinase β (ChoKβ) variant F352L, choline |