EC 2.7.1.32: choline kinase
TransferasesOpen in Browse
CatLog read 73 records for EC 2.7.1.32 from 3 papers, for 2 organisms. Names in these papers: choline kinase A-2 (CKA-2), choline kinase beta (CKβ), choline kinase α2 (ChoKα2), choline kinase β (ChoKβ) and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 32 records for EC 2.7.1.32 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.32 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Identification of critical residues of choline kinase A2 from Caenorhabditis elegans | Caenorhabditis elegans | 50 |
| Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity | Homo sapiens | 14 |
| Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition | Homo sapiens | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| choline kinase A-2 (CKA-2) | Caenorhabditis elegans | ATP | — | 1.7 | 44 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2), ATP |
| choline kinase A-2 (CKA-2) | Caenorhabditis elegans | choline | 72.3 | 1 | 73 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2), choline |
| choline kinase A-2 (CKA-2)variant C252S | Caenorhabditis elegans | ATP | — | 1 | 82 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant C252S, ATP |
| choline kinase A-2 (CKA-2)variant C252S | Caenorhabditis elegans | choline | 84.3 | 1 | 83 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant C252S, choline |
| choline kinase A-2 (CKA-2)variant D255E | Caenorhabditis elegans | ATP | — | 1.3 | 0.2 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant D255E, ATP |
| choline kinase A-2 (CKA-2)variant D255E | Caenorhabditis elegans | choline | 0.25 | 5.4 | 0.05 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant D255E, choline |
| choline kinase A-2 (CKA-2)variant E125A | Caenorhabditis elegans | ATP | — | 3.2 | 7 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125A, ATP |
| choline kinase A-2 (CKA-2)variant E125A | Caenorhabditis elegans | choline | 21 | 1.1 | 20 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125A, choline |
| choline kinase A-2 (CKA-2)variant E125D | Caenorhabditis elegans | ATP | — | 2.2 | 60 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125D, ATP |
| choline kinase A-2 (CKA-2)variant E125D | Caenorhabditis elegans | choline | 130 | 0.8 | 156 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125D, choline |
| choline kinase A-2 (CKA-2)variant E125Q | Caenorhabditis elegans | ATP | — | 4.2 | 7 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125Q, ATP |
| choline kinase A-2 (CKA-2)variant E125Q | Caenorhabditis elegans | choline | 31.4 | 1.6 | 19 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E125Q, choline |
| choline kinase A-2 (CKA-2)variant E134A | Caenorhabditis elegans | ATP | — | 1.7 | 56 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E134A, ATP |
| choline kinase A-2 (CKA-2)variant E134A | Caenorhabditis elegans | choline | 97.3 | 1.8 | 53 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E134A, choline |
| choline kinase A-2 (CKA-2)variant E151A | Caenorhabditis elegans | ATP | — | 4.5 | 20 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E151A, ATP |
| choline kinase A-2 (CKA-2)variant E151A | Caenorhabditis elegans | choline | 89.2 | 2.2 | 41 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E151A, choline |
| choline kinase A-2 (CKA-2)variant E303A | Caenorhabditis elegans | ATP | — | 5.4 | 1 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303A, ATP |
| choline kinase A-2 (CKA-2)variant E303A | Caenorhabditis elegans | choline | 7 | 10 | 1 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303A, choline |
| choline kinase A-2 (CKA-2)variant E303D | Caenorhabditis elegans | ATP | — | 6.9 | 6 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303D, ATP |
| choline kinase A-2 (CKA-2)variant E303D | Caenorhabditis elegans | choline | 38.7 | 3.6 | 11 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303D, choline |
| choline kinase A-2 (CKA-2)variant E303Q | Caenorhabditis elegans | ATP | — | 8.8 | 7 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303Q, ATP |
| choline kinase A-2 (CKA-2)variant E303Q | Caenorhabditis elegans | choline | 58.7 | 3.4 | 18 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E303Q, choline |
| choline kinase A-2 (CKA-2)variant E320A | Caenorhabditis elegans | ATP | — | 45 | 2 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E320A, ATP |
| choline kinase A-2 (CKA-2)variant E320A | Caenorhabditis elegans | choline | 79.9 | 3 | 26 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant E320A, choline |
| choline kinase A-2 (CKA-2)variant H253A | Caenorhabditis elegans | ATP | — | 1.9 | 23 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant H253A, ATP |
| choline kinase A-2 (CKA-2)variant H253A | Caenorhabditis elegans | choline | 42.9 | 1.6 | 26 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant H253A, choline |
| choline kinase A-2 (CKA-2)variant N254A | Caenorhabditis elegans | ATP | — | 1.2 | 2.3 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N254A, ATP |
| choline kinase A-2 (CKA-2)variant N254A | Caenorhabditis elegans | choline | 2.6 | 1 | 2.7 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N254A, choline |
| choline kinase A-2 (CKA-2)variant N260A | Caenorhabditis elegans | ATP | — | 3.1 | 0.08 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N260A, ATP |
| choline kinase A-2 (CKA-2)variant N260A | Caenorhabditis elegans | choline | 0.24 | 0.4 | 0.6 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N260A, choline |
| choline kinase A-2 (CKA-2)variant N308A | Caenorhabditis elegans | ATP | — | 2 | 10 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308A, ATP |
| choline kinase A-2 (CKA-2)variant N308A | Caenorhabditis elegans | choline | 20.8 | 1.5 | 14 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308A, choline |
| choline kinase A-2 (CKA-2)variant N308D | Caenorhabditis elegans | ATP | — | 1.5 | 58 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308D, ATP |
| choline kinase A-2 (CKA-2)variant N308D | Caenorhabditis elegans | choline | 84.6 | 1 | 87 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308D, choline |
| choline kinase A-2 (CKA-2)variant N308Q | Caenorhabditis elegans | ATP | — | 1 | 38 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308Q, ATP |
| choline kinase A-2 (CKA-2)variant N308Q | Caenorhabditis elegans | choline | 37.5 | 0.8 | 46 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N308Q, choline |
| choline kinase A-2 (CKA-2)variant N87A | Caenorhabditis elegans | ATP | — | 1.7 | 18 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N87A, ATP |
| choline kinase A-2 (CKA-2)variant N87A | Caenorhabditis elegans | choline | 29.7 | 1.8 | 16 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant N87A, choline |
| choline kinase A-2 (CKA-2)variant R111A | Caenorhabditis elegans | ATP | — | 7 | 4 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R111A, ATP |
| choline kinase A-2 (CKA-2)variant R111A | Caenorhabditis elegans | choline | 27.1 | 1.7 | 16 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R111A, choline |
| choline kinase A-2 (CKA-2)variant R149A | Caenorhabditis elegans | ATP | — | 2.2 | 18 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R149A, ATP |
| choline kinase A-2 (CKA-2)variant R149A | Caenorhabditis elegans | choline | 38.9 | 0.7 | 54 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R149A, choline |
| choline kinase A-2 (CKA-2)variant R149K | Caenorhabditis elegans | ATP | — | 2.3 | 38 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R149K, ATP |
| choline kinase A-2 (CKA-2)variant R149K | Caenorhabditis elegans | choline | 87.9 | 1.2 | 77 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant R149K, choline |
| choline kinase A-2 (CKA-2)variant S86A | Caenorhabditis elegans | ATP | — | 2.5 | 4 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant S86A, ATP |
| choline kinase A-2 (CKA-2)variant S86A | Caenorhabditis elegans | choline | 9.8 | 5 | 2 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant S86A, choline |
| choline kinase A-2 (CKA-2)variant S86T | Caenorhabditis elegans | ATP | — | 1.9 | 19 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant S86T, ATP |
| choline kinase A-2 (CKA-2)variant S86T | Caenorhabditis elegans | choline | 35.7 | 0.7 | 51 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant S86T, choline |
| choline kinase A-2 (CKA-2)variant W387A | Caenorhabditis elegans | ATP | — | 2.2 | 1.1 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant W387A, ATP |
| choline kinase A-2 (CKA-2)variant W387A | Caenorhabditis elegans | choline | 2.4 | 1.2 | 2.1 | pH 10, 37 °C | PMID 14960577 | Open record: choline kinase A-2 (CKA-2) variant W387A, choline |
| choline kinase beta (CKβ) | Homo sapiens | ATP | 37.58 | 0.8751 | 42.94 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), ATP |
| choline kinase beta (CKβ) | Homo sapiens | ATP | 54.39 | 0.65 | 83.69 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), ATP |
| choline kinase beta (CKβ) | Homo sapiens | choline | 30.1 | 0.62 | 48.54 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), choline |
| choline kinase beta (CKβ) | Homo sapiens | choline | 48.25 | 0.42 | 114.9 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), choline |
| choline kinase beta (CKβ) | Homo sapiens | ethanolamine | 10.71 | 0.26 | 41.19 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), ethanolamine |
| choline kinase beta (CKβ) | Homo sapiens | ethanolamine | 21.53 | 0.55 | 39.14 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ), ethanolamine |
| choline kinase beta (CKβ)variant S39D/S40D | Homo sapiens | ATP | 50.48 | 0.5853 | 86.24 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ) variant S39D/S40D, ATP |
| choline kinase beta (CKβ)variant S39D/S40D | Homo sapiens | choline | 45.31 | 0.46 | 98.5 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ) variant S39D/S40D, choline |
| choline kinase beta (CKβ)variant S39D/S40D | Homo sapiens | ethanolamine | 21.29 | 0.57 | 37.35 | pH 8.5, 37 °C | PMID 27149373 | Open record: choline kinase beta (CKβ) variant S39D/S40D, ethanolamine |
| choline kinase α1 (ChoKα1) | Homo sapiens | adenosine 5'-triphosphate | — | 0.76 | — | PMID 20299452 | Open record: choline kinase α1 (ChoKα1), adenosine 5'-triphosphate | |
| choline kinase α1 (ChoKα1) | Homo sapiens | choline | 76.8 | 0.18 | 430 calc. | PMID 20299452 | Open record: choline kinase α1 (ChoKα1), choline | |
| choline kinase α2 (ChoKα2) | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | PMID 20299452 | Open record: choline kinase α2 (ChoKα2), adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2) | Homo sapiens | choline | 47.3 | 0.086 | 550 calc. | PMID 20299452 | Open record: choline kinase α2 (ChoKα2), choline | |
| choline kinase α2 (ChoKα2)variant L401A | Homo sapiens | adenosine 5'-triphosphate | — | 0.55 | — | PMID 20299452 | Open record: choline kinase α2 (ChoKα2) variant L401A, adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2)variant L401A | Homo sapiens | choline | 49.5 | 0.107 | 463 calc. | PMID 20299452 | Open record: choline kinase α2 (ChoKα2) variant L401A, choline | |
| choline kinase α2 (ChoKα2)variant L401F | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | PMID 20299452 | Open record: choline kinase α2 (ChoKα2) variant L401F, adenosine 5'-triphosphate | |
| choline kinase α2 (ChoKα2)variant L401F | Homo sapiens | choline | 14 | 0.021 | 670 calc. | PMID 20299452 | Open record: choline kinase α2 (ChoKα2) variant L401F, choline | |
| choline kinase β (ChoKβ) | Homo sapiens | adenosine 5'-triphosphate | — | 0.4 | — | PMID 20299452 | Open record: choline kinase β (ChoKβ), adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ) | Homo sapiens | choline | 2.92 | 0.033 | 88 calc. | PMID 20299452 | Open record: choline kinase β (ChoKβ), choline | |
| choline kinase β (ChoKβ)variant F352A | Homo sapiens | adenosine 5'-triphosphate | — | 0.65 | — | PMID 20299452 | Open record: choline kinase β (ChoKβ) variant F352A, adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ)variant F352A | Homo sapiens | choline | 9.5 | 0.102 | 93 calc. | PMID 20299452 | Open record: choline kinase β (ChoKβ) variant F352A, choline | |
| choline kinase β (ChoKβ)variant F352L | Homo sapiens | adenosine 5'-triphosphate | — | 0.7 | — | PMID 20299452 | Open record: choline kinase β (ChoKβ) variant F352L, adenosine 5'-triphosphate | |
| choline kinase β (ChoKβ)variant F352L | Homo sapiens | choline | 4.58 | 0.041 | 110 calc. | PMID 20299452 | Open record: choline kinase β (ChoKβ) variant F352L, choline |