Values CatLog read from this paper
Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate Decarboxylase
PMID 26135041doi:10.1021/acs.biochem.5b00591Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (23 values) from this paper: orotidine 5'-monophosphate decarboxylase (ScOMPDC) from Saccharomyces cerevisiae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Q215A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 190 | 0.096 | 2 × 10³ | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Q215A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Q215A/R235A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 4.7 | 0.65 | 7.2 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Q215A/R235A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Q215A/Y217F | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 49 | 0.92 | 53 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Q215A/Y217F, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Q215A/Y217F/R235A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | — | — | 0.028 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Q215A/Y217F/R235A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant S154A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 16 | 0.055 | 290 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant S154A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant S154A/Q215A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 6.6 | 0.086 | 77 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant S154A/Q215A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Y217A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 8.2 | 0.62 | 13 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Y217A, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Y217F | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | 430 | 0.42 | 1.1 × 10³ | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Y217F, 5-fluoroorotidine 5'-monophosphate |
| orotidine 5'-monophosphate decarboxylase (ScOMPDC)variant Y217F/R235A | Saccharomyces cerevisiae | 5-fluoroorotidine 5'-monophosphate | — | — | 0.82 | pH 7.1, 25 °C | Open record: orotidine 5'-monophosphate decarboxylase (ScOMPDC) variant Y217F/R235A, 5-fluoroorotidine 5'-monophosphate |