CatLogenzyme kinetics catalog

Values CatLog read from this paper

Revisiting the Roles of Catalytic Residues in Human Ornithine Transcarbamylase

PMID 38940639doi:10.1021/acs.biochem.4c00206Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 22 records (65 values) from this paper: ornithine transcarbamylase (hOTC) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.

EC 2.1.3.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
ornithine transcarbamylase (hOTC)Homo sapienscarbamoyl phosphate290.21140Open
ornithine transcarbamylase (hOTC)Homo sapiensL-ornithine340.4875Open
ornithine transcarbamylase (hOTC)variant A152VHomo sapienscarbamoyl phosphate220.2975Open
ornithine transcarbamylase (hOTC)variant A152VHomo sapiensL-ornithine230.3372Open
ornithine transcarbamylase (hOTC)variant C303AHomo sapienscarbamoyl phosphate150.2173Open
ornithine transcarbamylase (hOTC)variant C303AHomo sapiensL-ornithine196.33Open
ornithine transcarbamylase (hOTC)variant D263NHomo sapienscarbamoyl phosphate0.250.540.48Open
ornithine transcarbamylase (hOTC)variant D263NHomo sapiensL-ornithine0.0881705.2 × 10⁻⁴ calc.Open
ornithine transcarbamylase (hOTC)variant E310QHomo sapienscarbamoyl phosphate8.50.3130Open
ornithine transcarbamylase (hOTC)variant E310QHomo sapiensL-ornithine102.24.5Open
ornithine transcarbamylase (hOTC)variant E98QHomo sapienscarbamoyl phosphate150.2755Open
ornithine transcarbamylase (hOTC)variant E98QHomo sapiensL-ornithine150.2854Open
ornithine transcarbamylase (hOTC)variant H107NHomo sapienscarbamoyl phosphate5.12.42.1Open
ornithine transcarbamylase (hOTC)variant H107NHomo sapiensL-ornithine5.70.3416Open
ornithine transcarbamylase (hOTC)variant H302LHomo sapienscarbamoyl phosphate9.55.61.8Open
ornithine transcarbamylase (hOTC)variant H302LHomo sapiensL-ornithine1081.3Open
ornithine transcarbamylase (hOTC)variant K307AHomo sapienscarbamoyl phosphate5.60.035170Open
ornithine transcarbamylase (hOTC)variant K307AHomo sapiensL-ornithine5.280.61Open
ornithine transcarbamylase (hOTC)variant K307EHomo sapienscarbamoyl phosphate1.60.03646Open
ornithine transcarbamylase (hOTC)variant K307EHomo sapiensL-ornithine21.51.4Open
ornithine transcarbamylase (hOTC)variant Q171AHomo sapienscarbamoyl phosphate2.91.71.8Open
ornithine transcarbamylase (hOTC)variant Q171AHomo sapiensL-ornithine2.61.12.3Open