EC 2.1.3.3: ornithine carbamoyltransferase

TransferasesOpen in Browse

CatLog read 221 records for EC 2.1.3.3 from 10 papers, for 7 organisms. Names in these papers: ornithine transcarbamylase, ornithine carbamoyltransferase, ornithine transcarbamoylase (anabolic OTC), ornithine carbamoyltransferase (OTCase) and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 83 records for EC 2.1.3.3 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.3.3 in Browse.

Papers

Papers with records for EC 2.1.3.3
Paper	Organisms	Records
Ornithine transcarbamylase from Streptococcus faecalis and bovine liver. II. Multiple binding sites for carbamyl-P and L-norvaline, correlation with steady state kinetics	Bos taurus, Streptococcus faecalis	36
Probing remote residues important for catalysis in Escherichia coli ornithine transcarbamoylase	Escherichia coli	30
Kinetic analysis of a new human ornithine carbamoyltransferase variant	Homo sapiens	30
Biochemical Characterization of Disease-Associated Variants of Human Ornithine Transcarbamylase	Homo sapiens	28
Yeast epiarginase regulation, an enzyme-enzyme activity control: identification of residues of ornithine carbamoyltransferase and arginase responsible for enzyme catalytic and regulatory activities	Saccharomyces cerevisiae	23
Revisiting the Roles of Catalytic Residues in Human Ornithine Transcarbamylase	Homo sapiens	22
Purification and properties of ornithine carbamoyltransferase from loggerhead turtle liver	Caretta caretta	20
Chemical rescue by guanidine derivatives of an arginine-substituted site-directed mutant of Escherichia coli ornithine transcarbamylase	Escherichia coli	12
Kinetics and equilibrium of the inactivation of ornithine transcarbamylases by pyridoxal 5'-phosphate	Bos taurus, Streptococcus faecalis	11
Metabolic enzymes from psychrophilic bacteria: challenge of adaptation to low temperatures in ornithine carbamoyltransferase from Moritella abyssi	Moritella abyssi	9

Records

Records for EC 2.1.3.3 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
ornithine carbamoyltransferase	Caretta caretta	carbamoyl phosphate	—	0.22	—	pH 7.8, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, carbamoyl phosphate
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.858	—	pH 7.8, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	14.04	—	pH 6.35, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.065	—	pH 6.35, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	4.73	—	pH 6.66, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.044	—	pH 6.66, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	2.73	—	pH 6.95, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.049	—	pH 6.95, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	2.04	—	pH 7.25, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.073	—	pH 7.25, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	0.94	—	pH 7.71, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.091	—	pH 7.71, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	0.51	—	pH 8, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.088	—	pH 8, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	0.2	—	pH 8.38, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.065	—	pH 8.38, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	0.21	—	pH 8.85, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.124	—	pH 8.85, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithineapparent Km	—	0.19	—	pH 9.95, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Caretta caretta	L-ornithine	—	0.157	—	pH 9.95, 37 °C	PMID 12108925	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	carbamoyl phosphate	—	0.16	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, carbamoyl phosphate
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	6.8	—	pH 6.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.022	—	pH 6.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	4.2	—	pH 6.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.026	—	pH 6.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	2.2	—	pH 6.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.025	—	pH 6.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	1.2	—	pH 7.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.037	—	pH 7.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.7	—	pH 7.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.043	—	pH 7.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.35	—	pH 7.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.037	—	pH 7.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.22	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.038	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.14	—	pH 8.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferase	Homo sapiens	L-ornithine	—	0.043	—	pH 8.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase, L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	carbamoyl phosphate	—	0.13	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), carbamoyl phosphate
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	6.8	—	pH 6.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.066	—	pH 6.75, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	2.5	—	pH 7.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.077	—	pH 7.2, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	1.4	—	pH 7.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.066	—	pH 7.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	1	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.19	—	pH 8, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.95	—	pH 8.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.39	—	pH 8.5, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.7	—	pH 9, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferasepatient mutant (OTC deficiency; mutation not characterized)	Homo sapiens	L-ornithine	—	0.47	—	pH 9, 37 °C	PMID 7397202	Open record: ornithine carbamoyltransferase patient mutant (OTC deficiency; mutation not characterized), L-ornithine
ornithine carbamoyltransferase (OTCase)	Saccharomyces cerevisiae	carbamoyl phosphate	—	0.1	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase), carbamoyl phosphate
ornithine carbamoyltransferase (OTCase)	Saccharomyces cerevisiae	L-ornithine	—	1.6	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase), L-ornithine
ornithine carbamoyltransferase (OTCase)variant C191M/C194N/F197V	Saccharomyces cerevisiae	L-ornithine	—	2.8	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant C191M/C194N/F197V, L-ornithine
ornithine carbamoyltransferase (OTCase)variant C289S	Saccharomyces cerevisiae	L-ornithine	—	10	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant C289S, L-ornithine
ornithine carbamoyltransferase (OTCase)variant D182N	Saccharomyces cerevisiae	L-ornithine	—	49	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant D182N, L-ornithine
ornithine carbamoyltransferase (OTCase)variant E123A	Saccharomyces cerevisiae	L-ornithine	—	2.6	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant E123A, L-ornithine
ornithine carbamoyltransferase (OTCase)variant E123S	Saccharomyces cerevisiae	L-ornithine	—	2.1	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant E123S, L-ornithine
ornithine carbamoyltransferase (OTCase)variant E256A	Saccharomyces cerevisiae	L-ornithine	—	10	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant E256A, L-ornithine
ornithine carbamoyltransferase (OTCase)variant E256Q	Saccharomyces cerevisiae	L-ornithine	—	1.2	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant E256Q, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K260A	Saccharomyces cerevisiae	L-ornithine	—	1	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K260A, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K260R	Saccharomyces cerevisiae	L-ornithine	—	1.2	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K260R, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K263A	Saccharomyces cerevisiae	L-ornithine	—	30	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K263A, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K263R	Saccharomyces cerevisiae	L-ornithine	—	20	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K263R, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K265A	Saccharomyces cerevisiae	L-ornithine	—	1.2	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K265A, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K265R	Saccharomyces cerevisiae	L-ornithine	—	1.1	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K265R, L-ornithine
ornithine carbamoyltransferase (OTCase)variant K268R	Saccharomyces cerevisiae	L-ornithine	—	1.1	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant K268R, L-ornithine
ornithine carbamoyltransferase (OTCase)variant L290Q	Saccharomyces cerevisiae	L-ornithine	—	2	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant L290Q, L-ornithine
ornithine carbamoyltransferase (OTCase)variant L290S	Saccharomyces cerevisiae	L-ornithine	—	2	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant L290S, L-ornithine
ornithine carbamoyltransferase (OTCase)variant N184Q	Saccharomyces cerevisiae	L-ornithine	—	34	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant N184Q, L-ornithine
ornithine carbamoyltransferase (OTCase)variant N185Q	Saccharomyces cerevisiae	L-ornithine	—	350	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant N185Q, L-ornithine
ornithine carbamoyltransferase (OTCase)variant Q294P	Saccharomyces cerevisiae	L-ornithine	—	1.3	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant Q294P, L-ornithine
ornithine carbamoyltransferase (OTCase)variant T68G	Saccharomyces cerevisiae	carbamoyl phosphate	—	2.4	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant T68G, carbamoyl phosphate
ornithine carbamoyltransferase (OTCase)variant T68G	Saccharomyces cerevisiae	L-ornithine	—	3.4	—	pH 8, 30 °C	PMID 12679340	Open record: ornithine carbamoyltransferase (OTCase) variant T68G, L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	carbamoyl phosphate	—	0.9	766	pH 9, 30 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), carbamoyl phosphate
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	carbamoyl phosphate	—	1	694	pH 9, 20 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), carbamoyl phosphate
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	carbamoyl phosphate	—	1.1	214	pH 9, 5 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), carbamoyl phosphate
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	690	45	15	pH 9, 30 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	750	22.49	33	pH 9, 25 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	694	8	87	pH 9, 20 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	546	5.67	97	pH 9, 15 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	382	3.34	114	pH 9, 10 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine carbamoyltransferase (OTCaseMab)	Moritella abyssi	L-ornithine	235	1.78	132	pH 9, 5 °C	PMID 12644485	Open record: ornithine carbamoyltransferase (OTCaseMab), L-ornithine
ornithine transcarbamoylase (anabolic OTC)	Escherichia coli	carbamoyl phosphate	410	0.27	1.5 × 10³	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC), carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)	Escherichia coli	L-ornithine	440	0.53	830	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC), L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant C273A	Escherichia coli	carbamoyl phosphate	140	0.26	560	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant C273A, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant C273A	Escherichia coli	L-ornithine	170	0.73	260	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant C273A, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant D140N	Escherichia coli	carbamoyl phosphate	360	1.4	290	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant D140N, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant D140N	Escherichia coli	L-ornithine	460	17	30	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant D140N, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant D231A	Escherichia coli	carbamoyl phosphate	0.48	0.15	3.4	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant D231A, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant D231A	Escherichia coli	L-ornithine	0.7	0.59	1.4	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant D231A, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant E299D	Escherichia coli	carbamoyl phosphate	120	0.22	620	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant E299D, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant E299D	Escherichia coli	L-ornithine	170	0.9	200	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant E299D, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant E299Q	Escherichia coli	carbamoyl phosphate	4.6	0.34	14	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant E299Q, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant E299Q	Escherichia coli	L-ornithine	5.1	0.33	16	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant E299Q, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant H272L	Escherichia coli	carbamoyl phosphate	4.2	0.93	5	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant H272L, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant H272L	Escherichia coli	L-ornithine	4.3	0.68	7.1	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant H272L, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant H272N	Escherichia coli	carbamoyl phosphate	180	0.5	360	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant H272N, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant H272N	Escherichia coli	L-ornithine	95	0.4	240	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant H272N, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant Q104L	Escherichia coli	carbamoyl phosphate	88	0.4	260	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Q104L, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant Q104L	Escherichia coli	L-ornithine	52	0.81	80	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Q104L, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant R57A	Escherichia coli	carbamoyl phosphate	7.5	0.28	27	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant R57A, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant R57A	Escherichia coli	L-ornithine	8.2	0.44	19	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant R57A, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant S61A	Escherichia coli	carbamoyl phosphate	74	0.3	250	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant S61A, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant S61A	Escherichia coli	L-ornithine	240	0.53	460	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant S61A, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant Y160F	Escherichia coli	carbamoyl phosphate	120	0.53	230	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y160F, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant Y160F	Escherichia coli	L-ornithine	110	1	100	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y160F, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant Y160S	Escherichia coli	carbamoyl phosphate	300	0.3	1 × 10³	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y160S, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant Y160S	Escherichia coli	L-ornithine	410	7.3	61	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y160S, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant Y229F	Escherichia coli	carbamoyl phosphate	150	0.33	440	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y229F, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant Y229F	Escherichia coli	L-ornithine	130	0.45	310	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y229F, L-ornithine
ornithine transcarbamoylase (anabolic OTC)variant Y229S	Escherichia coli	carbamoyl phosphate	290	0.32	920	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y229S, carbamoyl phosphate
ornithine transcarbamoylase (anabolic OTC)variant Y229S	Escherichia coli	L-ornithine	350	0.61	590	pH 8.5, 20 °C	PMID 32027716	Open record: ornithine transcarbamoylase (anabolic OTC) variant Y229S, L-ornithine
ornithine transcarbamylase	Bos taurus	acetyl phosphate	—	4	—	pH 8.5, 37 °C	PMID 4622304	Open record: ornithine transcarbamylase, acetyl phosphate
ornithine transcarbamylase	Bos taurus	L-lysine	—	60	—	pH 9.2, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-lysine
ornithine transcarbamylase	Bos taurus	L-ornithine	41	10	4.1 calc.	pH 6.14, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	L-ornithine	101	2.85	35.4 calc.	pH 6.75, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	L-ornithine	146	1.4	100 calc.	pH 7.1, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	L-ornithine	180	0.24	750 calc.	pH 7.88, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	L-ornithine	187	0.14	1.3 × 10³ calc.	pH 8.47, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	L-ornithine	187	0.14	1.3 × 10³ calc.	pH 8.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Bos taurus	ornithine	—	0.16	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase, ornithine
ornithine transcarbamylase	Bos taurus	ornithine	—	0.12	—	pH 8.5, 25 °C	PMID 16927	Open record: ornithine transcarbamylase, ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction I (one phosphopyridoxyllysine per trimer)	Bos taurus	ornithine	—	0.15	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction I (one phosphopyridoxyllysine per trimer), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction I (one phosphopyridoxyllysine per trimer)	Bos taurus	ornithine	—	0.095	—	pH 8.5, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction I (one phosphopyridoxyllysine per trimer), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction II (two phosphopyridoxyllysines per trimer)	Bos taurus	ornithine	—	0.13	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction II (two phosphopyridoxyllysines per trimer), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction II (two phosphopyridoxyllysines per trimer)	Bos taurus	ornithine	—	0.096	—	pH 8.5, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction II (two phosphopyridoxyllysines per trimer), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction III (three phosphopyridoxyllysines per trimer)	Bos taurus	ornithine	—	74	—	pH 8.5, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction III (three phosphopyridoxyllysines per trimer), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction IV (additional phosphopyridoxyl residue; kinetically similar to Fraction II)	Bos taurus	ornithine	—	0.14	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction IV (additional phosphopyridoxyl residue; kinetically similar to Fraction II), ornithine
ornithine transcarbamylasevariant phosphopyridoxyl derivative, Fraction V (additional phosphopyridoxyl residue; kinetically similar to Fraction III)	Bos taurus	ornithine	—	0.12	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative, Fraction V (additional phosphopyridoxyl residue; kinetically similar to Fraction III), ornithine
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateno rescue agent; in the text	0.095	0.22	0.43 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	200	0.6	330 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	23	0.28	83 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	11.3	12	0.94 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	1.8	4	0.46 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	1.3	5	0.27 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	4.3	4.8	0.90 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	0.13	1.6	0.083 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	43	0.35	120 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	3.3	2	1.7 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	0.88	0.24	3.7 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylasevariant R57G	Escherichia coli	carbamyl phosphateTable 2	0.6	0.68	0.88 calc.	pH 8.3, 25 °C	PMID 8973189	Open record: ornithine transcarbamylase variant R57G, carbamyl phosphate
ornithine transcarbamylase	Homo sapiens	carbamoyl phosphate	56	0.24	240		PMID 40059726	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Homo sapiens	ornithine	59	0.37	160		PMID 40059726	Open record: ornithine transcarbamylase, ornithine
ornithine transcarbamylasevariant A135E	Homo sapiens	carbamoyl phosphate	28	0.42	67		PMID 40059726	Open record: ornithine transcarbamylase variant A135E, carbamoyl phosphate
ornithine transcarbamylasevariant A135E	Homo sapiens	ornithine	32	0.7	46		PMID 40059726	Open record: ornithine transcarbamylase variant A135E, ornithine
ornithine transcarbamylasevariant C109A	Homo sapiens	carbamoyl phosphate	39	0.21	190		PMID 40059726	Open record: ornithine transcarbamylase variant C109A, carbamoyl phosphate
ornithine transcarbamylasevariant C109A	Homo sapiens	ornithine	47	0.75	63		PMID 40059726	Open record: ornithine transcarbamylase variant C109A, ornithine
ornithine transcarbamylasevariant C109R	Homo sapiens	carbamoyl phosphate	0.021	3.4	0.0062		PMID 40059726	Open record: ornithine transcarbamylase variant C109R, carbamoyl phosphate
ornithine transcarbamylasevariant C109R	Homo sapiens	ornithine	0.018	0.56	0.033		PMID 40059726	Open record: ornithine transcarbamylase variant C109R, ornithine
ornithine transcarbamylasevariant D175G	Homo sapiens	carbamoyl phosphate	21	0.54	38		PMID 40059726	Open record: ornithine transcarbamylase variant D175G, carbamoyl phosphate
ornithine transcarbamylasevariant D175G	Homo sapiens	ornithine	22	0.64	34		PMID 40059726	Open record: ornithine transcarbamylase variant D175G, ornithine
ornithine transcarbamylasevariant D196Y	Homo sapiens	carbamoyl phosphate	1.2	0.21	5.7		PMID 40059726	Open record: ornithine transcarbamylase variant D196Y, carbamoyl phosphate
ornithine transcarbamylasevariant D196Y	Homo sapiens	ornithine	1.5	55	0.028		PMID 40059726	Open record: ornithine transcarbamylase variant D196Y, ornithine
ornithine transcarbamylasevariant G83D	Homo sapiens	carbamoyl phosphate	58	0.73	81		PMID 40059726	Open record: ornithine transcarbamylase variant G83D, carbamoyl phosphate
ornithine transcarbamylasevariant G83D	Homo sapiens	ornithine	68	0.82	86		PMID 40059726	Open record: ornithine transcarbamylase variant G83D, ornithine
ornithine transcarbamylasevariant H117R	Homo sapiens	carbamoyl phosphate	3.9	0.052	75		PMID 40059726	Open record: ornithine transcarbamylase variant H117R, carbamoyl phosphate
ornithine transcarbamylasevariant H117R	Homo sapiens	ornithine	3.7	0.57	6.5		PMID 40059726	Open record: ornithine transcarbamylase variant H117R, ornithine
ornithine transcarbamylasevariant H302R	Homo sapiens	carbamoyl phosphate	0.116	3.8	0.032		PMID 40059726	Open record: ornithine transcarbamylase variant H302R, carbamoyl phosphate
ornithine transcarbamylasevariant H302R	Homo sapiens	ornithine	0.12	96	0.0012		PMID 40059726	Open record: ornithine transcarbamylase variant H302R, ornithine
ornithine transcarbamylasevariant K88N	Homo sapiens	carbamoyl phosphate	5.8	0.2	31		PMID 40059726	Open record: ornithine transcarbamylase variant K88N, carbamoyl phosphate
ornithine transcarbamylasevariant K88N	Homo sapiens	ornithine	7.5	2.8	28		PMID 40059726	Open record: ornithine transcarbamylase variant K88N, ornithine
ornithine transcarbamylasevariant N161D	Homo sapiens	carbamoyl phosphate	13	0.37	36		PMID 40059726	Open record: ornithine transcarbamylase variant N161D, carbamoyl phosphate
ornithine transcarbamylasevariant N161D	Homo sapiens	ornithine	15	3.4	4.6		PMID 40059726	Open record: ornithine transcarbamylase variant N161D, ornithine
ornithine transcarbamylasevariant R94T	Homo sapiens	carbamoyl phosphate	16	0.15	110		PMID 40059726	Open record: ornithine transcarbamylase variant R94T, carbamoyl phosphate
ornithine transcarbamylasevariant R94T	Homo sapiens	ornithine	16	0.34	47		PMID 40059726	Open record: ornithine transcarbamylase variant R94T, ornithine
ornithine transcarbamylasevariant S267R	Homo sapiens	carbamoyl phosphate	2.8	0.061	47		PMID 40059726	Open record: ornithine transcarbamylase variant S267R, carbamoyl phosphate
ornithine transcarbamylasevariant S267R	Homo sapiens	ornithine	3.9	42.7	0.091		PMID 40059726	Open record: ornithine transcarbamylase variant S267R, ornithine
ornithine transcarbamylasevariant Y176C	Homo sapiens	carbamoyl phosphate	12	0.53	24		PMID 40059726	Open record: ornithine transcarbamylase variant Y176C, carbamoyl phosphate
ornithine transcarbamylasevariant Y176C	Homo sapiens	ornithine	16	0.4	42		PMID 40059726	Open record: ornithine transcarbamylase variant Y176C, ornithine
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.0097	—	pH 6.56, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.045	—	pH 7.12, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.072	—	pH 7.37, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.176	—	pH 7.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.29	—	pH 8.41, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	carbamoyl phosphate	—	0.4	—	pH 8.8, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, carbamoyl phosphate
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	16	—	pH 6.56, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	17	—	pH 7.12, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	15	—	pH 7.66, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	24	—	pH 7.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	26	—	pH 8.41, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	citrulline	—	32	—	pH 8.8, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, citrulline
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	220	2.1	100 calc.	pH 6.56, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	700	1.15	610 calc.	pH 7.12, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	1.07 × 10³	0.97	1.1 × 10³ calc.	pH 7.37, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	2.29 × 10³	0.74	3.1 × 10³ calc.	pH 7.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	3.39 × 10³	0.68	5.0 × 10³ calc.	pH 8.41, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	3.58 × 10³	0.67	5.3 × 10³ calc.	pH 8.8, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine5 mM carbamyl-P	—	0.87	—	pH 7.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine	—	1.27	—	pH 7.1, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithineno added LiCl	—	0.82	—	25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	L-ornithine18 mM LiCl added	—	0.89	—	25 °C	PMID 4622304	Open record: ornithine transcarbamylase, L-ornithine
ornithine transcarbamylase	Streptococcus faecalis	phosphate	62	1.5	41 calc.	pH 6.56, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylase	Streptococcus faecalis	phosphate	89	0.8	110 calc.	pH 7.12, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylase	Streptococcus faecalis	phosphate	69	1.3	53 calc.	pH 7.66, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylase	Streptococcus faecalis	phosphate	72	1.8	40 calc.	pH 7.9, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylase	Streptococcus faecalis	phosphate	40	1.9	21 calc.	pH 8.41, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylase	Streptococcus faecalis	phosphate	15	1.6	9.4 calc.	pH 8.8, 25 °C	PMID 4622304	Open record: ornithine transcarbamylase, phosphate
ornithine transcarbamylasevariant phosphopyridoxyl derivative (three equilibration/NaBH4 reduction cycles; Vmax 3% of control)	Streptococcus faecalis	carbamyl-P	—	0.82	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative (three equilibration/NaBH4 reduction cycles; Vmax 3% of control), carbamyl-P
ornithine transcarbamylasevariant phosphopyridoxyl derivative (three equilibration/NaBH4 reduction cycles; Vmax 3% of control)	Streptococcus faecalis	ornithine	—	0.6	—	pH 8, 25 °C	PMID 16927	Open record: ornithine transcarbamylase variant phosphopyridoxyl derivative (three equilibration/NaBH4 reduction cycles; Vmax 3% of control), ornithine
ornithine transcarbamylase (hOTC)	Homo sapiens	carbamoyl phosphate	29	0.21	140		PMID 38940639	Open record: ornithine transcarbamylase (hOTC), carbamoyl phosphate
ornithine transcarbamylase (hOTC)	Homo sapiens	L-ornithine	34	0.48	75		PMID 38940639	Open record: ornithine transcarbamylase (hOTC), L-ornithine
ornithine transcarbamylase (hOTC)variant A152V	Homo sapiens	carbamoyl phosphate	22	0.29	75		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant A152V, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant A152V	Homo sapiens	L-ornithine	23	0.33	72		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant A152V, L-ornithine
ornithine transcarbamylase (hOTC)variant C303A	Homo sapiens	carbamoyl phosphate	15	0.21	73		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant C303A, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant C303A	Homo sapiens	L-ornithine	19	6.3	3		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant C303A, L-ornithine
ornithine transcarbamylase (hOTC)variant D263N	Homo sapiens	carbamoyl phosphate	0.25	0.54	0.48		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant D263N, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant D263N	Homo sapiens	L-ornithine	0.088	170	5.2 × 10⁻⁴ calc.		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant D263N, L-ornithine
ornithine transcarbamylase (hOTC)variant E310Q	Homo sapiens	carbamoyl phosphate	8.5	0.31	30		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant E310Q, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant E310Q	Homo sapiens	L-ornithine	10	2.2	4.5		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant E310Q, L-ornithine
ornithine transcarbamylase (hOTC)variant E98Q	Homo sapiens	carbamoyl phosphate	15	0.27	55		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant E98Q, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant E98Q	Homo sapiens	L-ornithine	15	0.28	54		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant E98Q, L-ornithine
ornithine transcarbamylase (hOTC)variant H107N	Homo sapiens	carbamoyl phosphate	5.1	2.4	2.1		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant H107N, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant H107N	Homo sapiens	L-ornithine	5.7	0.34	16		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant H107N, L-ornithine
ornithine transcarbamylase (hOTC)variant H302L	Homo sapiens	carbamoyl phosphate	9.5	5.6	1.8		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant H302L, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant H302L	Homo sapiens	L-ornithine	10	8	1.3		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant H302L, L-ornithine
ornithine transcarbamylase (hOTC)variant K307A	Homo sapiens	carbamoyl phosphate	5.6	0.035	170		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant K307A, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant K307A	Homo sapiens	L-ornithine	5.2	8	0.61		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant K307A, L-ornithine
ornithine transcarbamylase (hOTC)variant K307E	Homo sapiens	carbamoyl phosphate	1.6	0.036	46		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant K307E, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant K307E	Homo sapiens	L-ornithine	2	1.5	1.4		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant K307E, L-ornithine
ornithine transcarbamylase (hOTC)variant Q171A	Homo sapiens	carbamoyl phosphate	2.9	1.7	1.8		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant Q171A, carbamoyl phosphate
ornithine transcarbamylase (hOTC)variant Q171A	Homo sapiens	L-ornithine	2.6	1.1	2.3		PMID 38940639	Open record: ornithine transcarbamylase (hOTC) variant Q171A, L-ornithine