Values CatLog read from this paper
Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis
PMID 11467949doi:10.1021/bi0106787Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (19 values) from this paper: Vgb (streptogramin B lyase), Vgb orthologue (streptogramin B lyase) from Staphylococcus aureus, Bordetella pertussis, Streptomyces coelicolor.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Vgb (streptogramin B lyase) | Staphylococcus aureus | O-(N-tert-butyloxycarbonyl-L-phenylglycyl)-N-(3-hydroxypicolinyl)-L-threonine methyl ester | — | — | 0.15 | Open record: Vgb (streptogramin B lyase), O-(N-tert-butyloxycarbonyl-L-phenylglycyl)-N-(3-hydroxypicolinyl)-L-threonine methyl ester | |
| Vgb (streptogramin B lyase) | Staphylococcus aureus | pristinamycin IA | 2.9 | 0.019 | 150 | pH 7.5 | Open record: Vgb (streptogramin B lyase), pristinamycin IA |
| Vgb (streptogramin B lyase) | Staphylococcus aureus | quinupristin | 2.1 | 0.008 | 260 | pH 7.5 | Open record: Vgb (streptogramin B lyase), quinupristin |
| Vgb (streptogramin B lyase) | Staphylococcus aureus | quinupristinN-terminal His6 fusion (pET28a, NTA-agarose purified) | 1.8 | 0.018 | 100 | pH 7.5 | Open record: Vgb (streptogramin B lyase), quinupristin |
| Vgb orthologue (streptogramin B lyase) | Bordetella pertussis | quinupristin | 0.3 | 0.031 | 9.6 | pH 7.5 | Open record: Vgb orthologue (streptogramin B lyase), quinupristin |
| Vgb orthologue (streptogramin B lyase) | Bordetella pertussis | quinupristinN-terminal His6 fusion (pET28a, NTA-agarose purified) | 0.2 | 0.033 | 5.7 | pH 7.5 | Open record: Vgb orthologue (streptogramin B lyase), quinupristin |
| Vgb orthologue (streptogramin B lyase) | Streptomyces coelicolor | quinupristin | 2.8 | 0.027 | 100 | pH 7.5 | Open record: Vgb orthologue (streptogramin B lyase), quinupristin |