Values CatLog read from this paper
Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change
PMID 23787140doi:10.1016/j.jinorgbio.2013.05.006Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (12 values) from this paper: HIF prolyl-4-hydroxylase 2 (PHD2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| HIF prolyl-4-hydroxylase 2 (PHD2) | Homo sapiens | HIF-1α C-terminal oxygen degradation domain peptide HIF-1α(556-574) M561A/M568A, DLDLEALAPYIPADDDFQLno added NaCl | 0.0188 | 0.001 | 17 | pH 7, 37 °C | Open record: HIF prolyl-4-hydroxylase 2 (PHD2), HIF-1α C-terminal oxygen degradation domain peptide HIF-1α(556-574) M561A/M568A, DLDLEALAPYIPADDDFQL |
| HIF prolyl-4-hydroxylase 2 (PHD2) | Homo sapiens | HIF-1α C-terminal oxygen degradation domain peptide HIF-1α(556-574) M561A/M568A, DLDLEALAPYIPADDDFQL100 mM NaCl | 0.02 | 0.0042 | 5 | pH 7, 37 °C | Open record: HIF prolyl-4-hydroxylase 2 (PHD2), HIF-1α C-terminal oxygen degradation domain peptide HIF-1α(556-574) M561A/M568A, DLDLEALAPYIPADDDFQL |
| HIF prolyl-4-hydroxylase 2 (PHD2) | Homo sapiens | HIF-1α N-terminal oxygen degradation domain peptide HIF-1α(395-414) F413Y, DALTLLAPAAGDTIISLDYGno added NaCl | 0.0102 | 0.014 | 0.67 | pH 7, 37 °C | Open record: HIF prolyl-4-hydroxylase 2 (PHD2), HIF-1α N-terminal oxygen degradation domain peptide HIF-1α(395-414) F413Y, DALTLLAPAAGDTIISLDYG |
| HIF prolyl-4-hydroxylase 2 (PHD2) | Homo sapiens | HIF-1α N-terminal oxygen degradation domain peptide HIF-1α(395-414) F413Y, DALTLLAPAAGDTIISLDYG100 mM NaCl | 0.0103 | 0.011 | 0.83 | pH 7, 37 °C | Open record: HIF prolyl-4-hydroxylase 2 (PHD2), HIF-1α N-terminal oxygen degradation domain peptide HIF-1α(395-414) F413Y, DALTLLAPAAGDTIISLDYG |