CatLogenzyme kinetics catalog

Values CatLog read from this paper

Allosteric ensembles elucidate mechanisms of inhibition in the human soluble epoxide hydrolase

PMID 42086723doi:10.1038/s42003-026-10100-7Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (12 values) from this paper: soluble epoxide hydrolase (sEH) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.3.2.10

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
soluble epoxide hydrolase (sEH)Homo sapiens14(15)-epoxyeicosatrienoic acid5.410.01118480pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid4.72——pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid—0.01457—pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid——320pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)4.87——pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)—0.01247—pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)——390pH 7.4, 25 °COpen
soluble epoxide hydrolase (sEH)variant C522SHomo sapiens14(15)-epoxyeicosatrienoic acid3.790.02396160pH 7.4, 25 °COpen