CatLogenzyme kinetics catalog

EC 3.3.2.10: soluble epoxide hydrolase

HydrolasesOpen in Browse

CatLog read 43 records for EC 3.3.2.10 from 6 papers, for 3 organisms. Names in these papers: soluble epoxide hydrolase, soluble epoxide hydrolase (sEH), EH3 (ABHD9), epoxide hydrolase 3 (EH3) and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 59 records for EC 3.3.2.10 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.3.2.10 in Browse.

Papers

PaperOrganismsRecords
Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formationHomo sapiens10
EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxidesHomo sapiens8
Allosteric ensembles elucidate mechanisms of inhibition in the human soluble epoxide hydrolaseHomo sapiens8
The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphataseHomo sapiens, Rattus norvegicus7
Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling moleculesCaenorhabditis elegans6
Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human TissuesHomo sapiens4

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
EH3 (ABHD9)Homo sapiens11,12-epoxyeicosatrienoic acid—0.08400PMID 22798687Open
EH3 (ABHD9)Homo sapiens14,15-epoxyeicosatrienoic acid—0.13300PMID 22798687Open
EH3 (ABHD9)Homo sapiens8,9-epoxyeicosatrienoic acid—0.03250PMID 22798687Open
EH3 (ABHD9)Homo sapiens9,10-epoxyoctadec-11-enoic acid—0.025600PMID 22798687Open
epoxide hydrolase 3 (EH3)Homo sapiens13,14-epoxydocosapentaenoic acid0.080.004319pH 7.4, 37 °CPMID 34066758Open
epoxide hydrolase 3 (EH3)Homo sapiens14,15-epoxyeicosatrienoic acid0.0180.0760.24pH 7.4, 37 °CPMID 34066758Open
epoxide hydrolase 3 (EH3)Homo sapiens8,9-epoxyeicosatrienoic acid0.030.013pH 7.4, 37 °CPMID 34066758Open
epoxide hydrolase 3 (EH3)Homo sapienshepoxilin A30.0140.0141.01pH 7.4, 37 °CPMID 34066758Open
epoxide hydrolase CEEH1Caenorhabditis elegans12,13-epoxy-9-octadecenoate0.110.01149.6pH 7.4, 30 °CPMID 18267101Open
epoxide hydrolase CEEH1Caenorhabditis elegans9,10-epoxy-12-octadecenoate0.220.007529pH 7.4, 30 °CPMID 18267101Open
epoxide hydrolase CEEH1Caenorhabditis eleganstrans-1,3-diphenylpropene oxide120.1670PMID 18267101Open
epoxide hydrolase CEEH2Caenorhabditis elegans12,13-epoxy-9-octadecenoate0.0020.00191pH 7.4, 30 °CPMID 18267101Open
epoxide hydrolase CEEH2Caenorhabditis elegans9,10-epoxy-12-octadecenoate0.010.00841.2pH 7.4, 30 °CPMID 18267101Open
epoxide hydrolase CEEH2Caenorhabditis eleganstrans-1,3-diphenylpropene oxide——0.4PMID 18267101Open
soluble epoxide hydrolaseHomo sapiens14,15-epoxyeicosatrienoic acid50.007710pH 7, 30 °CPMID 24771868Open
soluble epoxide hydrolaseHomo sapiens4-nitrophenyl phosphateN-terminal domain; residues 1-221; C-terminal His6-tag0.0132.30.0057pH 7.8, 37 °CPMID 12574508Open
soluble epoxide hydrolaseHomo sapiens4-nitrophenyl phosphatefull-length; N-terminal strep-tag fusion (pASK-IBA7)0.00611.10.0055pH 7.8, 37 °CPMID 12574508Open
soluble epoxide hydrolaseHomo sapienstrans-1,3-diphenylpropene oxide0.990.0033300pH 7.4, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant C154YHomo sapiens14,15-epoxyeicosatrienoic acid150.00921.6 × 10³pH 7, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant C154YHomo sapienstrans-1,3-diphenylpropene oxide2.550.004640pH 7.4, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant K55RHomo sapiens14,15-epoxyeicosatrienoic acid7.50.00741 × 10³pH 7, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant K55RHomo sapienstrans-1,3-diphenylpropene oxide1.720.0058300pH 7.4, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant R103CHomo sapiens14,15-epoxyeicosatrienoic acid2.10.01210pH 7, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant R103CHomo sapienstrans-1,3-diphenylpropene oxide0.760.0059130pH 7.4, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant R287QHomo sapiens14,15-epoxyeicosatrienoic acid0.440.00950pH 7, 30 °CPMID 24771868Open
soluble epoxide hydrolasevariant R287QHomo sapienstrans-1,3-diphenylpropene oxide0.0760.01018pH 7.4, 30 °CPMID 24771868Open
soluble epoxide hydrolaseRattus norvegicus4-methylumbelliferyl phosphate——0.003pH 7.8PMID 12574508Open
soluble epoxide hydrolaseRattus norvegicus4-nitrophenyl phosphate0.840.243.5pH 7.8, 37 °CPMID 12574508Open
soluble epoxide hydrolaseRattus norvegicus4-nitrophenyl phosphate1.610.374.4pH 7.8, 37 °CPMID 12574508Open
soluble epoxide hydrolaseRattus norvegicustrans-stilbene oxide0.5——PMID 12574508Open
soluble epoxide hydrolaseRattus norvegicustrans-stilbene oxide—0.003—PMID 12574508Open
soluble epoxide hydrolase (sEH)Homo sapiens11,12-epoxyeicosatrienoic acid—0.00341.4 × 10³PMID 22798687Open
soluble epoxide hydrolase (sEH)Homo sapiens14(15)-epoxyeicosatrienoic acid5.410.01118480pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)Homo sapiens14,15-epoxyeicosatrienoic acid—0.015500PMID 22798687Open
soluble epoxide hydrolase (sEH)Homo sapiens8,9-epoxyeicosatrienoic acid—0.0017500PMID 22798687Open
soluble epoxide hydrolase (sEH)Homo sapiens9,10-epoxyoctadec-11-enoic acid—0.0015400PMID 22798687Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid4.72——pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid—0.01457—pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acid——320pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)4.87——pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)—0.01247—pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C423SHomo sapiens14(15)-epoxyeicosatrienoic acidwith 500 nM CuCl2 (protein:Cu2+ 1:2)——390pH 7.4, 25 °CPMID 42086723Open
soluble epoxide hydrolase (sEH)variant C522SHomo sapiens14(15)-epoxyeicosatrienoic acid3.790.02396160pH 7.4, 25 °CPMID 42086723Open