CatLogenzyme kinetics catalog

Values CatLog read from this paper

Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in…

PMID 15472229doi:10.1210/jc.2004-0331Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 42 records (42 values) from this paper: UGT1A8, UGT1A9, UGT1A1 and 3 more from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.1.17

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UGT1A1Homo sapiens2-hydroxyestradiol—0.165—pH 7.5Open
UGT1A1Homo sapiens2-methoxyestradiol—0.049—pH 7.5Open
UGT1A1Homo sapiens2-methoxyestrone—0.049—pH 7.5Open
UGT1A1Homo sapiens4-hydroxyestradiol3 (product 4-OHE2-3G)—0.038—pH 7.5Open
UGT1A1Homo sapiens4-hydroxyestradiol4 (product 4-OHE2-4G)—0.074—pH 7.5Open
UGT1A1Homo sapiens4-methoxyestradiol—0.014—pH 7.5Open
UGT1A1Homo sapiens4-methoxyestrone—0.103—pH 7.5Open
UGT1A10Homo sapiens2-methoxyestradiol—0.012—pH 7.5Open
UGT1A10Homo sapiensestradiol—0.017—pH 7.5Open
UGT1A3Homo sapiens2-hydroxyestradiol—0.479—pH 7.5Open
UGT1A3Homo sapiens2-hydroxyestrone—0.587—pH 7.5Open
UGT1A3Homo sapiens2-methoxyestradiol—0.049—pH 7.5Open
UGT1A8Homo sapiens2-hydroxyestradiol3 (product 2-OHE2-3G)—0.02—pH 7.5Open
UGT1A8Homo sapiens2-hydroxyestradiol2 (product 2-OHE2-2G)—0.102—pH 7.5Open
UGT1A8Homo sapiens2-hydroxyestrone3 (product 2-OHE1-3G)—0.04—pH 7.5Open
UGT1A8Homo sapiens2-hydroxyestrone2 (product 2-OHE1-2G)—0.052—pH 7.5Open
UGT1A8Homo sapiens2-methoxyestradiol—0.066—pH 7.5Open
UGT1A8Homo sapiens2-methoxyestrone—0.069—pH 7.5Open
UGT1A8Homo sapiens4-hydroxyestradiol3 (product 4-OHE2-3G)—0.118—pH 7.5Open
UGT1A8Homo sapiens4-hydroxyestradiol4 (product 4-OHE2-4G)—0.105—pH 7.5Open
UGT1A8Homo sapiens4-hydroxyestrone3 (product 4-OHE1-3G)—0.184—pH 7.5Open
UGT1A8Homo sapiens4-hydroxyestrone4 (product 4-OHE1-4G)—0.431—pH 7.5Open
UGT1A8Homo sapiens4-methoxyestradiol—0.008—pH 7.5Open
UGT1A8Homo sapiens4-methoxyestrone—0.111—pH 7.5Open
UGT1A8Homo sapiensestradiol—0.038—pH 7.5Open
UGT1A9Homo sapiens2-hydroxyestradiol3 (product 2-OHE2-3G)—0.024—pH 7.5Open
UGT1A9Homo sapiens2-hydroxyestradiol2 (product 2-OHE2-2G)—0.017—pH 7.5Open
UGT1A9Homo sapiens2-hydroxyestrone3 (product 2-OHE1-3G)—0.058—pH 7.5Open
UGT1A9Homo sapiens2-hydroxyestrone2 (product 2-OHE1-2G)—0.043—pH 7.5Open
UGT1A9Homo sapiens2-methoxyestradiol—0.053—pH 7.5Open
UGT1A9Homo sapiens2-methoxyestrone—0.126—pH 7.5Open
UGT1A9Homo sapiens4-hydroxyestradiol3 (product 4-OHE2-3G)—0.055—pH 7.5Open
UGT1A9Homo sapiens4-hydroxyestradiol4 (product 4-OHE2-4G)—0.053—pH 7.5Open
UGT1A9Homo sapiens4-hydroxyestrone3 (product 4-OHE1-3G)—0.241—pH 7.5Open
UGT1A9Homo sapiens4-hydroxyestrone4 (product 4-OHE1-4G)—0.142—pH 7.5Open
UGT1A9Homo sapiensestrone—0.054—pH 7.5Open
UGT2B7Homo sapiens2-hydroxyestradiol3 (product 2-OHE2-3G)—0.033—pH 7.5Open
UGT2B7Homo sapiens2-hydroxyestradiol2 (product 2-OHE2-2G)—0.033—pH 7.5Open
UGT2B7Homo sapiens4-hydroxyestradiol3 (product 4-OHE2-3G)—0.022—pH 7.5Open
UGT2B7Homo sapiens4-hydroxyestradiol4 (product 4-OHE2-4G)—0.01—pH 7.5Open
UGT2B7Homo sapiens4-hydroxyestrone—0.062—pH 7.5Open
UGT2B7Homo sapiensestradiol—0.01—pH 7.5Open