Values CatLog read from this paper

Cleavage of bovine collagen I by neutrophil collagenase MMP-8. Effect of pH on the catalytic properties as compared to synthetic substrates

PMID 10749856doi:10.1074/jbc.m000283200Open in Browse

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CatLog read 18 records (52 values) from this paper: neutrophil collagenase MMP-8 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.24.34

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen IUnprotonated	0.47	0.958	0.491	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen I1-protonated	0.47	2.08 × 10⁻⁴	2.26 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen I2-protonated	15	0.128	117	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen I3-protonated	1.12 × 10³	14.4	78.1	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen I4-protonated	0.0109	0.102	0.098	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	bovine collagen I5-protonated	0.0109	0.102	0.098	37 °C	Open record: neutrophil collagenase MMP-8, bovine collagen I
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)Unprotonated	246	0.0457	5.38 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)1-protonated	246	—	5.38 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)2-protonated	246	0.0457	5.38 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)3-protonated	250	—	8.96 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)4-protonated	517	0.0315	1.64 × 10⁴	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)5-protonated	180	0.0622	2.89 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-cyclohexylalanine-Gly-nor-valine-His-Ala-DPA-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-cyclohexylalanine-Gly-norvaline-His-Ala-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)Unprotonated	164	0.0208	7.88 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)1-protonated	164	0.0184	8.91 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)2-protonated	164	0.0184	8.91 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)3-protonated	324	0.0265	1.22 × 10⁴	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)4-protonated	562	0.046	1.22 × 10⁴	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)
neutrophil collagenase MMP-8	Homo sapiens	MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)5-protonated	148	0.046	3.22 × 10³	37 °C	Open record: neutrophil collagenase MMP-8, MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 ((7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-Ala-Arg-NH2)