CatLogenzyme kinetics catalog

Values CatLog read from this paper

Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin

PMID 11964170doi:10.1042/0264-6021:3630697Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 48 records (60 values) from this paper: neprilysin 2 (NEP2), secreted isoform NEP2(s), neprilysin (NEP), neprilysin 2 (NEP2), membrane-bound isoform NEP2(m) from Rattus norvegicus, Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.24.11

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
neprilysin (NEP)Homo sapiens3-methoxysuccinyl-Gly-Leu-Phe-7-amido-4-methylcoumarin220.0827037 °COpen
neprilysin (NEP)Homo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH213——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensArg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg25——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensAsp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu7——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensAsp-Tyr-Met-Gly-Trp-Met23——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensAsp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH212.5——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensCCK-8 (sulphated)8.8——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensGly-Gly-Phe-Met17——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensGly-Trp-Met-Asp-Phe-NH28.3——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapienspGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH22——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensPhe-Gly-Leu-Met-NH212——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensPhe-Phe-Gly-Leu-Met-NH230——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensrANP-(1-28)6.7——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapienssuccinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin370.0752337 °COpen
neprilysin (NEP)Homo sapienssuccinyl-Ala-Ala-Val-7-amido-4-methylcoumarin230.123037 °COpen
neprilysin (NEP)Homo sapiensTrp-Met-Asp-Phe-NH26.7——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensTyr-Gly-Ala-Phe-Met27——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensTyr-Gly-Gly-Phe-Leu20——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensTyr-Gly-Gly-Phe-Leu-NH23.3——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensTyr-Gly-Gly-Phe-Met22——pH 7.2, 37 °COpen
neprilysin (NEP)Homo sapiensTyr-Gly-Gly-Phe-Met-NH213——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), membrane-bound isoform NEP2(m)Rattus norvegicus3-methoxysuccinyl-Gly-Leu-Phe-7-amido-4-methylcoumarin—0.023—37 °COpen
neprilysin 2 (NEP2), membrane-bound isoform NEP2(m)Rattus norvegicussuccinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin—0.027—37 °COpen
neprilysin 2 (NEP2), membrane-bound isoform NEP2(m)Rattus norvegicussuccinyl-Ala-Ala-Val-7-amido-4-methylcoumarin—0.04—37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicus3-methoxysuccinyl-Gly-Leu-Phe-7-amido-4-methylcoumarin11.50.03532837 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH26——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2—0.013—pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusArg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg2.5——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusAsp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu3——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusAsp-Tyr-Met-Gly-Trp-Met34.5——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusAsp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH213.2——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusCCK-8 (sulphated)6.2——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusGly-Gly-Phe-Met8.5——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusGly-Trp-Met-Asp-Phe-NH24——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicuspGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH28.5——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicuspGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2—0.032—pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusPhe-Gly-Leu-Met-NH222.8——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusPhe-Phe-Gly-Leu-Met-NH250——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusPhe-Phe-Gly-Leu-Met-NH2—0.081—pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusrANP-(1-28)2——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicussuccinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin8.50.0517037 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicussuccinyl-Ala-Ala-Val-7-amido-4-methylcoumarin13.80.113837 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Ala-Phe-Met42——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Gly-Phe-Leu2.7——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Gly-Phe-Leu-NH20.33——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Gly-Phe-Met9——pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Gly-Phe-Met—0.019—pH 7.2, 37 °COpen
neprilysin 2 (NEP2), secreted isoform NEP2(s)Rattus norvegicusTyr-Gly-Gly-Phe-Met-NH20.33——pH 7.2, 37 °COpen