Values CatLog read from this paper
Kinetic mechanism of protein N-terminal methyltransferase 1
PMID 25771539doi:10.1074/jbc.m114.626846Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (33 values) from this paper: protein N-terminal methyltransferase 1 (NTMT1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | N,N-dimethyl-SPKRIAKRRS-NH2 | 0.0098 | 0.0043 | 2.3 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), N,N-dimethyl-SPKRIAKRRS-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | N-methyl-SPKRIAKRRS-NH2 | 0.0097 | 0.0014 | 6.8 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), N-methyl-SPKRIAKRRS-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | S-adenosyl-L-methionineuntagged (His6 tag removed with thrombin) | 0.0095 | 0.0117 | 0.82 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), S-adenosyl-L-methionine |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | S-adenosyl-L-methionineHis6-tagged (His-NTMT1) | 0.0038 | 0.008 | 0.48 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), S-adenosyl-L-methionine |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | S-adenosyl-L-methionineinitial velocity study: RCC1-10 varied at fixed AdoMet 12.5 | — | 0.0136 | — | pH 7.5 | Open record: protein N-terminal methyltransferase 1 (NTMT1), S-adenosyl-L-methionine |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | S-adenosyl-L-methionineinitial velocity study: AdoMet varied at fixed RCC1-10 1; 2 | 0.023 | 0.0061 | 3.8 calc. | pH 7.5 | Open record: protein N-terminal methyltransferase 1 (NTMT1), S-adenosyl-L-methionine |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIA-NH2 | 0.0093 | 0.0032 | 3 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIA-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRR-NH2 | 0.0088 | 0.0014 | 6.3 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRR-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRRS-NH2 | 0.0073 | 8.9 × 10⁻⁴ | 8.2 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRRS-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRRS-NH2initial velocity study: RCC1-10 varied at fixed AdoMet 12.5 | 0.0098 | 0.0016 | 6.1 calc. | pH 7.5 | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRRS-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRRS-NH2initial velocity study: AdoMet varied at fixed RCC1-10 1; 2 | — | 0.0023 | — | pH 7.5 | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRRS-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRRSPP-NH2untagged (His6 tag removed with thrombin) | 0.0095 | 0.0031 | 3 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRRSPP-NH2 |
| protein N-terminal methyltransferase 1 (NTMT1) | Homo sapiens | SPKRIAKRRSPP-NH2His6-tagged (His-NTMT1) | 0.013 | 0.0049 | 2.7 | pH 7.5, 37 °C | Open record: protein N-terminal methyltransferase 1 (NTMT1), SPKRIAKRRSPP-NH2 |