Values CatLog read from this paper
Effect of an amino acid insertion into the omega loop region of a class C beta-lactamase on its substrate specificity
PMID 9671516doi:10.1021/bi980184iOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 35 records (94 values) from this paper: class C beta-lactamase, class C beta-lactamase GC1 from Enterobacter cloacae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| class C beta-lactamase | Enterobacter cloacae | ampicillin | 0.36 | 9.7 × 10⁻⁴ | 370 | pH 7, 30 °C | Open record: class C beta-lactamase, ampicillin |
| class C beta-lactamase | Enterobacter cloacae | benzylpenicillin | 10.1 | 0.0031 | 3.3 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase, benzylpenicillin |
| class C beta-lactamase | Enterobacter cloacae | ceftazidime | 0.007 | — | 3.3 | pH 7, 30 °C | Open record: class C beta-lactamase, ceftazidime |
| class C beta-lactamase | Enterobacter cloacae | cefuroxime | 0.024 | 7 × 10⁻⁵ | 330 | pH 7, 30 °C | Open record: class C beta-lactamase, cefuroxime |
| class C beta-lactamase | Enterobacter cloacae | cephalothin | 84.8 | 0.01 | 8.2 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase, cephalothin |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | ampicillin | 0.25 | 0.001 | 250 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), ampicillin |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | aztreonam | 6 × 10⁻⁴ | — | — | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), aztreonam |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | benzylpenicillin | 6.3 | 0.0029 | 2.2 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), benzylpenicillin |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | ceftazidime | 2.7 | 0.441 | 3.3 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), ceftazidime |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | cefuroxime | 3.4 | 0.0033 | 1 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), cefuroxime |
| class C beta-lactamaseP99-210-1A (one Ala inserted after Arg210) | Enterobacter cloacae | cephalothin | 124 | 0.039 | 3.2 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-1A (one Ala inserted after Arg210), cephalothin |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | ampicillin | 0.16 | 9.9 × 10⁻⁴ | 160 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), ampicillin |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | aztreonam | 0.0056 | — | — | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), aztreonam |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | benzylpenicillin | 3.7 | 0.003 | 1.2 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), benzylpenicillin |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | ceftazidime | 3.1 | 0.614 | 4.4 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), ceftazidime |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | cefuroxime | 19.4 | 0.032 | 600 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), cefuroxime |
| class C beta-lactamaseP99-210-2A (two Ala inserted after Arg210) | Enterobacter cloacae | cephalothin | 59.3 | 0.037 | 1.6 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-2A (two Ala inserted after Arg210), cephalothin |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | ampicillin | 0.6 | 0.0025 | 240 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), ampicillin |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | aztreonam | 0.009 | — | — | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), aztreonam |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | benzylpenicillin | 5.5 | 0.0034 | 1.6 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), benzylpenicillin |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | ceftazidime | 6.5 | 0.575 | 7.2 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), ceftazidime |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | cefuroxime | 50.4 | 0.046 | 1.1 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), cefuroxime |
| class C beta-lactamaseP99-210-3A (three Ala inserted after Arg210) | Enterobacter cloacae | cephalothin | 94 | 0.034 | 2.8 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-3A (three Ala inserted after Arg210), cephalothin |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | ampicillin | 0.73 | 0.008 | 90 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), ampicillin |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | aztreonam | 0.05 | — | — | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), aztreonam |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | benzylpenicillin | 8.6 | 0.025 | 340 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), benzylpenicillin |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | ceftazidime | 12.1 | 0.821 | 8 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), ceftazidime |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | cefuroxime | 178 | 0.912 | 190 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), cefuroxime |
| class C beta-lactamaseP99-210-4A (four Ala inserted after Arg210) | Enterobacter cloacae | cephalothin | 83.6 | 0.148 | 560 | pH 7, 30 °C | Open record: class C beta-lactamase P99-210-4A (four Ala inserted after Arg210), cephalothin |
| class C beta-lactamase GC1 | Enterobacter cloacae | ampicillin | 0.52 | 0.0043 | 120 | pH 7, 30 °C | Open record: class C beta-lactamase GC1, ampicillin |
| class C beta-lactamase GC1 | Enterobacter cloacae | aztreonam | 0.011 | — | — | pH 7, 30 °C | Open record: class C beta-lactamase GC1, aztreonam |
| class C beta-lactamase GC1 | Enterobacter cloacae | benzylpenicillin | 5.7 | 0.0031 | 1.8 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase GC1, benzylpenicillin |
| class C beta-lactamase GC1 | Enterobacter cloacae | ceftazidime | 11 | 0.919 | 1.2 | pH 7, 30 °C | Open record: class C beta-lactamase GC1, ceftazidime |
| class C beta-lactamase GC1 | Enterobacter cloacae | cefuroxime | 24.1 | 0.026 | 920 | pH 7, 30 °C | Open record: class C beta-lactamase GC1, cefuroxime |
| class C beta-lactamase GC1 | Enterobacter cloacae | cephalothin | 74.8 | 0.031 | 2.4 × 10³ | pH 7, 30 °C | Open record: class C beta-lactamase GC1, cephalothin |