CatLogenzyme kinetics catalog

Values CatLog read from this paper

Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes

PMID 15769885doi:10.1124/dmd.104.003178Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (12 values) from this paper: UDP-glucuronosyltransferase (pooled human liver microsomes), UGT1A1, UGT1A9 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.1.17

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UDP-glucuronosyltransferase (pooled human liver microsomes)Homo sapiensgrepafloxacin—5.2—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase (pooled human liver microsomes)Homo sapienslevofloxacin—10—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase (pooled human liver microsomes)Homo sapiensmoxifloxacin—1.9—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase (pooled human liver microsomes)Homo sapienssitafloxacin—3.7—pH 7.4, 37 °COpen
UGT1A1Homo sapiensgrepafloxacin—2.7—pH 7.4, 37 °COpen
UGT1A1Homo sapienslevofloxacin—6—pH 7.4, 37 °COpen
UGT1A1Homo sapiensmoxifloxacin—3.4—pH 7.4, 37 °COpen
UGT1A1Homo sapienssitafloxacin—1.9—pH 7.4, 37 °COpen
UGT1A9Homo sapiensgrepafloxacin—2.1—pH 7.4, 37 °COpen
UGT1A9Homo sapienslevofloxacin—2.6—pH 7.4, 37 °COpen
UGT1A9Homo sapiensmoxifloxacin—2.1—pH 7.4, 37 °COpen
UGT1A9Homo sapienssitafloxacin—6.3—pH 7.4, 37 °COpen