Values CatLog read from this paper
Involvement of glutamate 399 and lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenase
PMID 9228057doi:10.1074/jbc.272.30.18823Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 16 records (23 values) from this paper: aldehyde dehydrogenase, mitochondrial (ALDH2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
EC 1.2.1.3, EC 1.2.1.19, EC 1.2.1.24, EC 1.2.1.36, EC 1.2.1.46
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aldehyde dehydrogenase, mitochondrial (ALDH2) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.027 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2), nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2) | Homo sapiens | propanalTable I | 3.2 | 5 × 10⁻⁴ | 6.3 × 10³ calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2), propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2) | Homo sapiens | propanalin the text | — | — | 6.3 × 10³ | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2), propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399D | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.078 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399D, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399D | Homo sapiens | propanal | 1.6 | 4 × 10⁻⁴ | 4.0 × 10³ calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399D, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399H | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.21 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399H, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399H | Homo sapiens | propanalTable I | 0.16 | 6 × 10⁻⁴ | 270 calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399H, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399H | Homo sapiens | propanalin the text | — | — | 270 | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399H, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399K | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.34 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399K, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399K | Homo sapiens | propanal | 0.017 | 9 × 10⁻⁴ | 19 calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399K, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399Q | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.12 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399Q, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399Q | Homo sapiens | propanal | 0.33 | 3 × 10⁻⁴ | 1.1 × 10³ calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant E399Q, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192E | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.048 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant K192E, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192E | Homo sapiens | propanal | 0.055 | 4 × 10⁻⁴ | 140 calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant K192E, propanal |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192Q | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 3.6 | — | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant K192Q, nicotinamide adenine dinucleotide (oxidized) |
| aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192Q | Homo sapiens | propanal | 0.58 | 0.0035 | 170 calc. | pH 7.4 | Open record: aldehyde dehydrogenase, mitochondrial (ALDH2) variant K192Q, propanal |