CatLogenzyme kinetics catalog

EC 1.2.1.46: formaldehyde dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 26 records for EC 1.2.1.46 from 2 papers, for 1 organism. Names in these papers: aldehyde dehydrogenase, mitochondrial (ALDH2), ALDH2 (mitochondrial aldehyde dehydrogenase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 45 records for EC 1.2.1.46 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.2.1.46 in Browse.

Papers

PaperOrganismsRecords
Involvement of glutamate 399 and lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenaseHomo sapiens16
Catalytic contribution of threonine 244 in human ALDH2Homo sapiens10

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
aldehyde dehydrogenase, mitochondrial (ALDH2)Homo sapiensnicotinamide adenine dinucleotide (oxidized)—0.027—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)Homo sapienspropanalTable I3.25 × 10⁻⁴6.3 × 10³ calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)Homo sapienspropanalin the text——6.3 × 10³pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399DHomo sapiensnicotinamide adenine dinucleotide (oxidized)—0.078—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399DHomo sapienspropanal1.64 × 10⁻⁴4.0 × 10³ calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399HHomo sapiensnicotinamide adenine dinucleotide (oxidized)—0.21—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399HHomo sapienspropanalTable I0.166 × 10⁻⁴270 calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399HHomo sapienspropanalin the text——270pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399KHomo sapiensnicotinamide adenine dinucleotide (oxidized)—0.34—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399KHomo sapienspropanal0.0179 × 10⁻⁴19 calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399QHomo sapiensnicotinamide adenine dinucleotide (oxidized)—0.12—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant E399QHomo sapienspropanal0.333 × 10⁻⁴1.1 × 10³ calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192EHomo sapiensnicotinamide adenine dinucleotide (oxidized)—0.048—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192EHomo sapienspropanal0.0554 × 10⁻⁴140 calc.pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192QHomo sapiensnicotinamide adenine dinucleotide (oxidized)—3.6—pH 7.4PMID 9228057Open
aldehyde dehydrogenase, mitochondrial (ALDH2)variant K192QHomo sapienspropanal0.580.0035170 calc.pH 7.4PMID 9228057Open
ALDH2 (mitochondrial aldehyde dehydrogenase)Homo sapienschloroacetaldehyde7.70.039200pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)Homo sapiensNAD+—0.048158pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244AHomo sapienschloroacetaldehyde40.313.2pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244AHomo sapiensNAD+—2.11.8pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244GHomo sapienschloroacetaldehyde0.630.05212.2pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244GHomo sapiensNAD+—0.193.3pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244SHomo sapienschloroacetaldehyde0.470.01333pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244SHomo sapiensNAD+—0.0945pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244VHomo sapienschloroacetaldehyde2.50.465.5pH 7.4PMID 23295226Open
ALDH2 (mitochondrial aldehyde dehydrogenase)variant T244VHomo sapiensNAD+—0.396.5pH 7.4PMID 23295226Open