Values CatLog read from this paper

A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1

PMID 11756418doi:10.1074/jbc.m110566200Open in Browse

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CatLog read 5 records (15 values) from this paper: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.6.1.56

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase)Homo sapiens2-hydroxy-2'-deoxyadenosine 5'-triphosphate28.70.00873.3 × 10³pH 8, 30 °COpen record: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase), 2-hydroxy-2'-deoxyadenosine 5'-triphosphate
hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase)Homo sapiens8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate25.90.01511.71 × 10³pH 8, 30 °COpen record: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase), 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate
hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase)variant D119AHomo sapiens8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate9.540.0302310pH 8, 30 °COpen record: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase) variant D119A, 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate
hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase)variant F27AHomo sapiens2-hydroxy-2'-deoxyadenosine 5'-triphosphate310.0171.82 × 10³pH 8, 30 °COpen record: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase) variant F27A, 2-hydroxy-2'-deoxyadenosine 5'-triphosphate
hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase)variant F27AHomo sapiens8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate25.10.0403620pH 8, 30 °COpen record: hMTH1 (human MutT homolog-1, oxidized purine nucleoside triphosphatase) variant F27A, 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate