Values CatLog read from this paper
Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation. Competition for cofactor sites on thrombin determines its fate
PMID 12794066doi:10.1074/jbc.m305364200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 20 records (20 values) from this paper: thrombin from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| thrombin | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptidefibrinogen-enhanced | — | — | 2.84 × 10³ | pH 7.4, 37 °C | Open record: thrombin, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombin | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptideno cofactor present (direct activation) | — | — | 330 | pH 7.4, 37 °C | Open record: thrombin, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombin | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptidefibrinogen-enhanced | — | — | 2.29 × 10³ | pH 7.4, 37 °C | Open record: thrombin, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombin | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptideno cofactor present (direct activation) | — | — | 180 | pH 7.4, 37 °C | Open record: thrombin, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombin | Homo sapiens | fibrinogen Aα-chain, release of fibrinopeptide A | — | — | 4.54 × 10³ | pH 7.4, 37 °C | Open record: thrombin, fibrinogen Aα-chain, release of fibrinopeptide A |
| thrombin | Homo sapiens | fibrinogen Bβ-chain, release of fibrinopeptide B | — | — | 1.38 × 10³ | pH 7.4, 37 °C | Open record: thrombin, fibrinogen Bβ-chain, release of fibrinopeptide B |
| thrombinvariant H66A | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide | — | — | 580 | pH 7.4, 37 °C | Open record: thrombin variant H66A, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant H66A | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide | — | — | 330 | pH 7.4, 37 °C | Open record: thrombin variant H66A, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant H66A | Homo sapiens | fibrinogen Aα-chain, release of fibrinopeptide A | — | — | 530 | pH 7.4, 37 °C | Open record: thrombin variant H66A, fibrinogen Aα-chain, release of fibrinopeptide A |
| thrombinvariant H66A | Homo sapiens | fibrinogen Bβ-chain, release of fibrinopeptide B | — | — | 150 | pH 7.4, 37 °C | Open record: thrombin variant H66A, fibrinogen Bβ-chain, release of fibrinopeptide B |
| thrombinvariant N74A | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide | — | — | 1.49 × 10³ | pH 7.4, 37 °C | Open record: thrombin variant N74A, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant N74A | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide | — | — | 940 | pH 7.4, 37 °C | Open record: thrombin variant N74A, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant N74A | Homo sapiens | fibrinogen Aα-chain, release of fibrinopeptide A | — | — | 1.78 × 10³ | pH 7.4, 37 °C | Open record: thrombin variant N74A, fibrinogen Aα-chain, release of fibrinopeptide A |
| thrombinvariant N74A | Homo sapiens | fibrinogen Bβ-chain, release of fibrinopeptide B | — | — | 620 | pH 7.4, 37 °C | Open record: thrombin variant N74A, fibrinogen Bβ-chain, release of fibrinopeptide B |
| thrombinvariant R233A | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide | — | — | 18 | pH 7.4, 37 °C | Open record: thrombin variant R233A, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant R233A | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide | — | — | 11 | pH 7.4, 37 °C | Open record: thrombin variant R233A, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant Y71A | Homo sapiens | coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide | — | — | 110 | pH 7.4, 37 °C | Open record: thrombin variant Y71A, coagulation factor XIII, Leu-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant Y71A | Homo sapiens | coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide | — | — | 38 | pH 7.4, 37 °C | Open record: thrombin variant Y71A, coagulation factor XIII, Val-34 polymorphic form of the A-subunit activation peptide |
| thrombinvariant Y71A | Homo sapiens | fibrinogen Aα-chain, release of fibrinopeptide A | — | — | 23 | pH 7.4, 37 °C | Open record: thrombin variant Y71A, fibrinogen Aα-chain, release of fibrinopeptide A |
| thrombinvariant Y71A | Homo sapiens | fibrinogen Bβ-chain, release of fibrinopeptide B | — | — | 11 | pH 7.4, 37 °C | Open record: thrombin variant Y71A, fibrinogen Bβ-chain, release of fibrinopeptide B |