CatLogenzyme kinetics catalog

EC 1.1.1.19: glucuronate reductase

OxidoreductasesOpen in Browse

CatLog read 27 records for EC 1.1.1.19 from 4 papers, for 2 organisms. Names in these papers: AKR1A1, hexonate dehydrogenase, aldehyde reductase AKR1A4 (ALDR), AKR1A1 (aldehyde reductase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 45 records for EC 1.1.1.19 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.19 in Browse.

Papers

PaperOrganismsRecords
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family membersHomo sapiens14
Polyol-pathway enzymes of human brain. Partial purification and properties of aldose reductase and hexonate dehydrogenaseHomo sapiens10
Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydesMus musculus2
Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroidsHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
AKR1A1Homo sapiens1,2-Naphthoquinone14.680.144103pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens16-Ketoestrone7.080.21333pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens2-Chlorobenzaldehyde0.150.6570.33pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens2-Nitrobenzaldehyde0.050.0540.83pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens3-Chlorobenzaldehyde7.372.4133.3pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens3-Nitrobenzaldehyde1.681.0081.7pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens4-Carboxybenzaldehyde6.970.024280pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens4-Chlorobenzaldehyde1.73.0660.5pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens4-Nitrobenzaldehyde6.950.19137pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiens9,10-Phenanthrenequinone0.830.1525pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiensPyridine-2-aldehyde0.050.1340.5pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiensPyridine-3-aldehyde6.180.59710pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiensPyridine-4-aldehyde6.20.7948.3pH 7, 25 °CPMID 10510318Open
AKR1A1Homo sapiensSuccinic semialdehyde9.330.23142pH 7, 25 °CPMID 10510318Open
AKR1A1 (aldehyde reductase)Homo sapiens(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)—0.063.3PMID 19464995Open
aldehyde reductase AKR1A4 (ALDR)Mus musculus1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine0.01130.01111pH 7, 37 °CPMID 17381426Open
aldehyde reductase AKR1A4 (ALDR)Mus musculusMethylglyoxal7.631.17pH 7, 25 °CPMID 17381426Open
hexonate dehydrogenaseHomo sapiens3-nitrobenzaldehyde—2.4—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiens4-Chlorobenzaldehyde—5.6—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiens4-nitrobenzaldehyde—0.145—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensBenzaldehyde—3—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensD-Glucose—390—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensD-Glucuronate—4.6—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensD-Xylose—260—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensDL-Glyceraldehyde—5—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapiensNADPH—0.0045—pH 6.2, 30 °CPMID 6773519Open
hexonate dehydrogenaseHomo sapienspyridine-3-carbaldehyde—1.2—pH 6.2, 30 °CPMID 6773519Open