EC 1.1.1.20: glucuronolactone reductase

OxidoreductasesOpen in Browse

CatLog read 17 records for EC 1.1.1.20 from 3 papers, for 2 organisms. Names in these papers: AKR1A1, aldehyde reductase AKR1A4 (ALDR), AKR1A1 (aldehyde reductase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 15 records for EC 1.1.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.20 in Browse.

Papers

Papers with records for EC 1.1.1.20
PaperOrganismsRecords
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family membersHomo sapiens14
Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydesMus musculus2
Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroidsHomo sapiens1

Records

Records for EC 1.1.1.20 read from the paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaperOpen record
AKR1A1Homo sapiens1,2-Naphthoquinone14.680.144103pH 7, 25 °CPMID 10510318Open record: AKR1A1, 1,2-Naphthoquinone
AKR1A1Homo sapiens16-Ketoestrone7.080.21333pH 7, 25 °CPMID 10510318Open record: AKR1A1, 16-Ketoestrone
AKR1A1Homo sapiens2-Chlorobenzaldehyde0.150.6570.33pH 7, 25 °CPMID 10510318Open record: AKR1A1, 2-Chlorobenzaldehyde
AKR1A1Homo sapiens2-Nitrobenzaldehyde0.050.0540.83pH 7, 25 °CPMID 10510318Open record: AKR1A1, 2-Nitrobenzaldehyde
AKR1A1Homo sapiens3-Chlorobenzaldehyde7.372.4133.3pH 7, 25 °CPMID 10510318Open record: AKR1A1, 3-Chlorobenzaldehyde
AKR1A1Homo sapiens3-Nitrobenzaldehyde1.681.0081.7pH 7, 25 °CPMID 10510318Open record: AKR1A1, 3-Nitrobenzaldehyde
AKR1A1Homo sapiens4-Carboxybenzaldehyde6.970.024280pH 7, 25 °CPMID 10510318Open record: AKR1A1, 4-Carboxybenzaldehyde
AKR1A1Homo sapiens4-Chlorobenzaldehyde1.73.0660.5pH 7, 25 °CPMID 10510318Open record: AKR1A1, 4-Chlorobenzaldehyde
AKR1A1Homo sapiens4-Nitrobenzaldehyde6.950.19137pH 7, 25 °CPMID 10510318Open record: AKR1A1, 4-Nitrobenzaldehyde
AKR1A1Homo sapiens9,10-Phenanthrenequinone0.830.1525pH 7, 25 °CPMID 10510318Open record: AKR1A1, 9,10-Phenanthrenequinone
AKR1A1Homo sapiensPyridine-2-aldehyde0.050.1340.5pH 7, 25 °CPMID 10510318Open record: AKR1A1, Pyridine-2-aldehyde
AKR1A1Homo sapiensPyridine-3-aldehyde6.180.59710pH 7, 25 °CPMID 10510318Open record: AKR1A1, Pyridine-3-aldehyde
AKR1A1Homo sapiensPyridine-4-aldehyde6.20.7948.3pH 7, 25 °CPMID 10510318Open record: AKR1A1, Pyridine-4-aldehyde
AKR1A1Homo sapiensSuccinic semialdehyde9.330.23142pH 7, 25 °CPMID 10510318Open record: AKR1A1, Succinic semialdehyde
AKR1A1 (aldehyde reductase)Homo sapiens(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)—0.063.3PMID 19464995Open record: AKR1A1 (aldehyde reductase), (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)
aldehyde reductase AKR1A4 (ALDR)Mus musculus1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine0.01130.01111pH 7, 37 °CPMID 17381426Open record: aldehyde reductase AKR1A4 (ALDR), 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine
aldehyde reductase AKR1A4 (ALDR)Mus musculusMethylglyoxal7.631.17pH 7, 25 °CPMID 17381426Open record: aldehyde reductase AKR1A4 (ALDR), Methylglyoxal