CatLogenzyme kinetics catalog

EC 1.1.1.283: methylglyoxal reductase (NADPH)

OxidoreductasesOpen in Browse

CatLog read 19 records for EC 1.1.1.283 from 2 papers, for 2 organisms. Names in these papers: SakR1 (aldo-keto reductase AKR11B3), Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 7 records for EC 1.1.1.283 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.283 in Browse.

Papers

PaperOrganismsRecords
Methylglyoxal detoxification by an aldo-keto reductase in the cyanobacterium Synechococcus sp. PCC 7002Synechococcus sp. PCC 700211
Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2Saccharomyces cerevisiae8

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)Saccharomyces cerevisiaeisovaleraldehyde23.180.14161.0pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant F132ASaccharomyces cerevisiaeisovaleraldehyde62.410.18342.7pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant F85ASaccharomyces cerevisiaeisovaleraldehyde5.9411.120.53pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant V162ASaccharomyces cerevisiaeisovaleraldehyde52.570.2261.5pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant Y128ASaccharomyces cerevisiaeisovaleraldehyde1.440.672.14pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant Y128FSaccharomyces cerevisiaeisovaleraldehyde38.980.23166.6pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant Y198ASaccharomyces cerevisiaeisovaleraldehyde9.294.12.27pH 7.5, 30 °CPMID 24879127Open
Gre2 (NADPH-dependent methylglyoxal/isovaleraldehyde reductase)variant Y198FSaccharomyces cerevisiaeisovaleraldehyde15.530.12126.3pH 7.5, 30 °CPMID 24879127Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 70022-Nitrobenzaldehyde1.310.314.3pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 70023-Nitrobenzaldehyde1.1150.913.7pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 70024-Nitrobenzaldehyde1.2430.851.47pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002Benzaldehyde1.0451.690.62pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002D-Galactose0.681600.0043pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002D-Glucose0.6154450.00133pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002D-Xylose1.2151040.0117pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002DL-Glyceraldehyde0.5180.560.92pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002Isopentaldehyde0.6481.330.48pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002L-Arabinose1.2732340.0055pH 6, 25 °CPMID 16804176Open
SakR1 (aldo-keto reductase AKR11B3)Synechococcus sp. PCC 7002Methylglyoxal0.8470.089.8pH 6, 25 °CPMID 16804176Open