EC 1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

OxidoreductasesOpen in Browse

CatLog read 125 records for EC 1.1.1.49 from 15 papers, for 13 organisms. Names in these papers: glucose-6-phosphate dehydrogenase (G6PD), glucose 6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase (G6PDH) and 16 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 125 records for EC 1.1.1.49 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.49 in Browse.

Papers

Papers with records for EC 1.1.1.49
Paper	Organisms	Records
Glucose-6-phosphate dehydrogenase in barley roots: kinetic properties and localisation of the isoforms	Hordeum vulgare	15
The cofactor preference of glucose-6-phosphate dehydrogenase from Escherichia coli--modeling the physiological production of reduced cofactors	Escherichia coli	12
On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase	Leuconostoc mesenteroides	12
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: a unique bifunctional enzyme from Plasmodium falciparum	Homo sapiens, Plasmodium falciparum	11
Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi	Trypanosoma cruzi	10
Engineering a thermostable highly active glucose 6-phosphate dehydrogenase and its application to hydrogen production in vitro	Zymomonas mobilis	10
Improved genetic screening with zygosity detection through multiplex high-resolution melting curve analysis and biochemical characterisation for G6PD deficiency	Homo sapiens	10
Glucose-6-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: expression of the g6pd gene and characterization of an extremely thermophilic enzyme	Thermotoga maritima	9
Kinetic properties of human placental glucose-6-phosphate dehydrogenase	Homo sapiens	8
Catalytic Properties of NADP-Reducing Enzymes from Streptococcus cristatus ATCC 51100	Streptococcus cristatus	8
Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PD(Plymouth) and G6PD(Mahidol): Evidence for defective protein folding as the basis of…	Homo sapiens	6
High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase	Plasmodium falciparum	4
Purification and characterization of glucose-6-phosphate dehydrogenase from Aspergillus niger and Aspergillus nidulans	Aspergillus nidulans, Aspergillus niger	4
Glucose 6-phosphate dehydrogenase from larval Taenia crassiceps (cysticerci): purification and properties	Taenia crassiceps	3
Characterization of enzymes involved in the central metabolism of Gluconobacter oxydans	Gluconobacter oxydans	3

Records

Records for EC 1.1.1.49 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
cytosolic Glc6PDH (soluble fraction)	Hordeum vulgare	glucose-6-phosphate	—	0.41	—	pH 8	PMID 11525521	Open record: cytosolic Glc6PDH (soluble fraction), glucose-6-phosphate
G6PD Mahidolvariant G163S	Homo sapiens	D-glucose 6-phosphate	207	0.0507	4.09 × 10³	pH 8, 25 °C	PMID 17959407	Open record: G6PD Mahidol variant G163S, D-glucose 6-phosphate
G6PD Mahidolvariant G163S	Homo sapiens	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.00646	3.21 × 10⁴	pH 8, 25 °C	PMID 17959407	Open record: G6PD Mahidol variant G163S, nicotinamide adenine dinucleotide phosphate (oxidized)
G6PD Plymouthvariant G163D	Homo sapiens	D-glucose 6-phosphate	249	0.0444	5.6 × 10³	pH 8, 25 °C	PMID 17959407	Open record: G6PD Plymouth variant G163D, D-glucose 6-phosphate
G6PD Plymouthvariant G163D	Homo sapiens	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.0048	5.21 × 10⁴	pH 8, 25 °C	PMID 17959407	Open record: G6PD Plymouth variant G163D, nicotinamide adenine dinucleotide phosphate (oxidized)
G6PD WT	Homo sapiens	D-glucose 6-phosphate	251	0.0458	5.48 × 10³	pH 8, 25 °C	PMID 17959407	Open record: G6PD WT, D-glucose 6-phosphate
G6PD WT	Homo sapiens	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.00467	5.37 × 10⁴	pH 8, 25 °C	PMID 17959407	Open record: G6PD WT, nicotinamide adenine dinucleotide phosphate (oxidized)
Glc6PDH 1	Hordeum vulgare	glucose-6-phosphate10 mM MgCl2; 0.15 mM NADP+ (standard assay)	—	1.03	—	pH 8	PMID 11525521	Open record: Glc6PDH 1, glucose-6-phosphate
Glc6PDH 1	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+; with 2 mM ATP plus Mg2+ (10 mM)	—	1.06	—	pH 8	PMID 11525521	Open record: Glc6PDH 1, glucose-6-phosphate
Glc6PDH 1	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+	—	1.21	—	pH 8	PMID 11525521	Open record: Glc6PDH 1, glucose-6-phosphate
Glc6PDH 1	Hordeum vulgare	NADP+	—	0.009	—	pH 8	PMID 11525521	Open record: Glc6PDH 1, NADP+
Glc6PDH 2	Hordeum vulgare	glucose-6-phosphate10 mM MgCl2; 0.15 mM NADP+ (standard assay)	—	0.5	—	pH 8	PMID 11525521	Open record: Glc6PDH 2, glucose-6-phosphate
Glc6PDH 2	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+; with 2 mM ATP plus Mg2+ (10 mM)	—	0.48	—	pH 8	PMID 11525521	Open record: Glc6PDH 2, glucose-6-phosphate
Glc6PDH 2	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+	—	0.65	—	pH 8	PMID 11525521	Open record: Glc6PDH 2, glucose-6-phosphate
Glc6PDH 2	Hordeum vulgare	NADP+	—	0.007	—	pH 8	PMID 11525521	Open record: Glc6PDH 2, NADP+
Glc6PDH major chromatofocusing peak (pI 5.55; corresponds to Glc6PDH 2)	Hordeum vulgare	glucose-6-phosphate	—	0.56	—	pH 8	PMID 11525521	Open record: Glc6PDH major chromatofocusing peak (pI 5.55; corresponds to Glc6PDH 2), glucose-6-phosphate
Glc6PDH minor chromatofocusing peak (pI 4.84; corresponds to Glc6PDH 1)	Hordeum vulgare	glucose-6-phosphate	—	0.97	—	pH 8	PMID 11525521	Open record: Glc6PDH minor chromatofocusing peak (pI 4.84; corresponds to Glc6PDH 1), glucose-6-phosphate
glucose 6-phosphate dehydrogenasevariant D177N	Leuconostoc mesenteroides	glucose 6-phosphateNADP-linked reaction; cosubstrate NADP+	1.1	0.117	9.3	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant D177N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant D177N	Leuconostoc mesenteroides	glucose 6-phosphateNAD-linked reaction; cosubstrate NAD+	4.85	0.29	17	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant D177N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant D177N	Leuconostoc mesenteroides	NAD+	—	1.43	3.3	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant D177N, NAD+
glucose 6-phosphate dehydrogenasevariant D177N	Leuconostoc mesenteroides	NADP+	—	0.0082	130	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant D177N, NADP+
glucose 6-phosphate dehydrogenasevariant H178N	Leuconostoc mesenteroides	glucose 6-phosphateNADP-linked reaction; cosubstrate NADP+	13.88	42.9	0.33	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H178N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant H178N	Leuconostoc mesenteroides	glucose 6-phosphateNAD-linked reaction; cosubstrate NAD+	47.5	13.6	3.3	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H178N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant H178N	Leuconostoc mesenteroides	NAD+	—	0.95	50	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H178N, NAD+
glucose 6-phosphate dehydrogenasevariant H178N	Leuconostoc mesenteroides	NADP+	—	0.0152	920	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H178N, NADP+
glucose 6-phosphate dehydrogenasevariant H240N	Leuconostoc mesenteroides	glucose 6-phosphateNADP-linked reaction; cosubstrate NADP+	0.0067	1.28	0.005	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H240N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant H240N	Leuconostoc mesenteroides	glucose 6-phosphateNAD-linked reaction; cosubstrate NAD+	0.02	0.8	0.017	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H240N, glucose 6-phosphate
glucose 6-phosphate dehydrogenasevariant H240N	Leuconostoc mesenteroides	NAD+	—	0.81	0.017	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H240N, NAD+
glucose 6-phosphate dehydrogenasevariant H240N	Leuconostoc mesenteroides	NADP+	—	0.0088	0.83	pH 7.6, 25 °C	PMID 9485426	Open record: glucose 6-phosphate dehydrogenase variant H240N, NADP+
glucose 6-phosphate dehydrogenase	Taenia crassiceps	D-glucose 6-phosphate	34	0.014	2.43 × 10³	pH 7.8, 25 °C	PMID 18297308	Open record: glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase	Taenia crassiceps	nicotinamide adenine dinucleotide phosphate (oxidized)in the text	—	0.0013	—	pH 7.8, 25 °C	PMID 18297308	Open record: glucose 6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase	Taenia crassiceps	nicotinamide adenine dinucleotide phosphate (oxidized)Table 2	34	—	2.61 × 10⁴	pH 7.8, 25 °C	PMID 18297308	Open record: glucose 6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase (Gox0145, G6PDH)	Gluconobacter oxydans	D-glucose 6-phosphate	44.1	0.28	157	pH 7, 25 °C	PMID 20676631	Open record: glucose 6-phosphate dehydrogenase (Gox0145, G6PDH), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (Gox0145, G6PDH)	Gluconobacter oxydans	NAD+	—	0.74	—	pH 7, 25 °C	PMID 20676631	Open record: glucose 6-phosphate dehydrogenase (Gox0145, G6PDH), NAD+
glucose 6-phosphate dehydrogenase (Gox0145, G6PDH)	Gluconobacter oxydans	NADP+	—	0.0264	—	pH 7, 25 °C	PMID 20676631	Open record: glucose 6-phosphate dehydrogenase (Gox0145, G6PDH), NADP+
glucose 6-phosphate dehydrogenase (ZmG6PDH)	Zymomonas mobilis	D-glucose 6-phosphate	305	0.078	3.9 × 10³ calc.	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (ZmG6PDH)	Zymomonas mobilis	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.0143	—	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/F277I/Q324H/M381I/V443I/S470I (Mut 3-1)	Zymomonas mobilis	D-glucose 6-phosphate	261	0.073	3.6 × 10³ calc.	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/F277I/Q324H/M381I/V443I/S470I (Mut 3-1), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/F277I/Q324H/M381I/V443I/S470I (Mut 3-1)	Zymomonas mobilis	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.0199	—	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/F277I/Q324H/M381I/V443I/S470I (Mut 3-1), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/Q324H/M381I/V443I/S470I (Mut 2-1)	Zymomonas mobilis	D-glucose 6-phosphate	306	0.099	3.1 × 10³ calc.	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/Q324H/M381I/V443I/S470I (Mut 2-1), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/Q324H/M381I/V443I/S470I (Mut 2-1)	Zymomonas mobilis	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.0225	—	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/Q324H/M381I/V443I/S470I (Mut 2-1), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/Q324H/V443I/S470I (Mut 1-1)	Zymomonas mobilis	D-glucose 6-phosphate	329	0.151	2.18 × 10³ calc.	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/Q324H/V443I/S470I (Mut 1-1), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant A117S/Q324H/V443I/S470I (Mut 1-1)	Zymomonas mobilis	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.024	—	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant A117S/Q324H/V443I/S470I (Mut 1-1), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant L99I/A117S/G225S/F277I/Q324H/M381I/V443I/S470I/A476V (Mut 4-1)	Zymomonas mobilis	D-glucose 6-phosphate	288	0.081	3.6 × 10³ calc.	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant L99I/A117S/G225S/F277I/Q324H/M381I/V443I/S470I/A476V (Mut 4-1), D-glucose 6-phosphate
glucose 6-phosphate dehydrogenase (ZmG6PDH)variant L99I/A117S/G225S/F277I/Q324H/M381I/V443I/S470I/A476V (Mut 4-1)	Zymomonas mobilis	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.0159	—	pH 7.5, 30 °C	PMID 29480380	Open record: glucose 6-phosphate dehydrogenase (ZmG6PDH) variant L99I/A117S/G225S/F277I/Q324H/M381I/V443I/S470I/A476V (Mut 4-1), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase	Aspergillus nidulans	D-glucose 6-phosphate	—	0.092	—	pH 7.5, 30 °C	PMID 8277259	Open record: glucose-6-phosphate dehydrogenase, D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase	Aspergillus nidulans	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.03	—	pH 7.5, 30 °C	PMID 8277259	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase	Aspergillus niger	D-glucose 6-phosphate	—	0.153	—	pH 7.5, 30 °C	PMID 8277259	Open record: glucose-6-phosphate dehydrogenase, D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase	Aspergillus niger	nicotinamide adenine dinucleotide phosphate (oxidized)	—	0.026	—	pH 7.5, 30 °C	PMID 8277259	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase	Homo sapiens	2-deoxyglucose-6-phosphate	43	0.87	48.9	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, 2-deoxyglucose-6-phosphate
glucose-6-phosphate dehydrogenase	Homo sapiens	galactose-6-phosphate	157	10	15.7	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, galactose-6-phosphate
glucose-6-phosphate dehydrogenase	Homo sapiens	glucose-6-phosphate	296	—	7.4 × 10³	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, glucose-6-phosphate
glucose-6-phosphate dehydrogenase	Homo sapiens	nicotinamide adenine dinucleotide phosphate (NADP+)cosubstrate glucose-6-phosphate	296	—	1.48 × 10⁴	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (NADP+)
glucose-6-phosphate dehydrogenase	Homo sapiens	nicotinamide adenine dinucleotide phosphate (NADP+)cosubstrate galactose-6-phosphate	—	0.02	—	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (NADP+)
glucose-6-phosphate dehydrogenase	Homo sapiens	nicotinamide adenine dinucleotide phosphate (NADP+)2-dG6P fixed at 0.3 mM	—	0.03	—	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (NADP+)
glucose-6-phosphate dehydrogenase	Homo sapiens	nicotinamide adenine dinucleotide phosphate (NADP+)2-dG6P fixed at 1.5 mM	—	0.01	—	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (NADP+)
glucose-6-phosphate dehydrogenase	Homo sapiens	nicotinamide hypoxanthine dinucleotide phosphate	98	0.0205	4.8 × 10³	pH 7.4, 37 °C	PMID 11311853	Open record: glucose-6-phosphate dehydrogenase, nicotinamide hypoxanthine dinucleotide phosphate
glucose-6-phosphate dehydrogenase (G6PD)	Homo sapiens	glucose-6-phosphate	354.6	0.0473	7.50 × 10³ calc.		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)	Homo sapiens	NADP^+	—	0.0083	—		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD), NADP^+
glucose-6-phosphate dehydrogenase (G6PD)variant G131V (G6PD Chinese-4)	Homo sapiens	glucose-6-phosphate	164.7	0.0468	3.52 × 10³ calc.		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant G131V (G6PD Chinese-4), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)variant G131V (G6PD Chinese-4)	Homo sapiens	NADP^+	—	0.0074	—		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant G131V (G6PD Chinese-4), NADP^+
glucose-6-phosphate dehydrogenase (G6PD)variant G131V/R459L (G6PD Chinese-4 + Canton)	Homo sapiens	glucose-6-phosphate	30.1	0.0452	666 calc.		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant G131V/R459L (G6PD Chinese-4 + Canton), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)variant G131V/R459L (G6PD Chinese-4 + Canton)	Homo sapiens	NADP^+	—	0.0082	—		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant G131V/R459L (G6PD Chinese-4 + Canton), NADP^+
glucose-6-phosphate dehydrogenase (G6PD)variant R227W (G6PD Radlowo)	Homo sapiens	glucose-6-phosphate	15.9	0.0355	448 calc.		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant R227W (G6PD Radlowo), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)variant R227W (G6PD Radlowo)	Homo sapiens	NADP^+	—	0.0107	—		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant R227W (G6PD Radlowo), NADP^+
glucose-6-phosphate dehydrogenase (G6PD)variant R459L (G6PD Canton)	Homo sapiens	glucose-6-phosphate	61.7	0.0254	2.43 × 10³ calc.		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant R459L (G6PD Canton), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)variant R459L (G6PD Canton)	Homo sapiens	NADP^+	—	0.0101	—		PMID 40078033	Open record: glucose-6-phosphate dehydrogenase (G6PD) variant R459L (G6PD Canton), NADP^+
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	2-deoxy-glucose-6-phosphate	18	35	0.5	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), 2-deoxy-glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	glucose-6-phosphate	35	0.2	175	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	nicotinamide adenine dinucleotide (oxidized)	11	12	0.9	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	nicotinamide adenine dinucleotide phosphate (oxidized)apparent Km	—	0.04	—	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	nicotinamide adenine dinucleotide phosphate (oxidized)kcat per subunit	35	—	—	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	nicotinamide adenine dinucleotide phosphate (oxidized)	—	—	890	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	nicotinamide adenine dinucleotide phosphate (oxidized)40 µM NADPH added (product inhibitor); apparent Km	—	0.06	—	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	thionicotinamide adenine dinucleotide (oxidized)	21	1.5	14	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), thionicotinamide adenine dinucleotide (oxidized)
glucose-6-phosphate dehydrogenase (G6PD)	Thermotoga maritima	thionicotinamide adenine dinucleotide phosphate (oxidized)	80	0.02	4 × 10³	pH 7.4, 80 °C	PMID 12435510	Open record: glucose-6-phosphate dehydrogenase (G6PD), thionicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	glucose-6-phosphateNADP 8-600 µM and G6P 0.12-2.10 mM varied; cosubstrate NADP	—	0.174	—	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	glucose-6-phosphateNAD 1.9-35.3 mM and G6P 1-12 mM varied; cosubstrate NAD	—	1.245	—	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	glucose-6-phosphatecompetitive inhibition model global fit; cosubstrate NADP	165	0.163	1.01 × 10³ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), glucose-6-phosphate
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NAD+initial rates; NAD 1.9-35.3 mM and G6P 1-12 mM varied	288	5.09	56.6 calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NAD+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NAD+progress curves to equilibrium (NAD <450 µM; Table 3	240	3.389	71 calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NAD+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NAD+progress curves to equilibrium (NAD <450 µM; Table 3	257	3.638	70.6 calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NAD+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NAD+initial rates; 200 µl reaction; 0.6 cm path length	—	6	—	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NAD+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NADP+initial rates; NADP 8-600 µM and G6P 0.12-2.10 mM varied	174	0.0075	2.3 × 10⁴ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NADP+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NADP+initial rates; competitive inhibition model global fit	176	0.0053	3.3 × 10⁴ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NADP+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NADP+progress curves to equilibrium (18 curves; NADP <450 µM	152	0.0045	3.4 × 10⁴ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NADP+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NADP+progress curves to equilibrium (18 curves; NADP <450 µM	158	0.0062	2.5 × 10⁴ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NADP+
glucose-6-phosphate dehydrogenase (G6PDH)	Escherichia coli	NADP+initial rates; mixed-inhibition model global fit	178	0.011	1.6 × 10⁴ calc.	pH 8, 25 °C	PMID 22519976	Open record: glucose-6-phosphate dehydrogenase (G6PDH), NADP+
glucose-6-phosphate dehydrogenase (hG6PD)	Homo sapiens	D-glucose 6-phosphatecosubstrate NADP+ (200 uM)	64.6	0.116	557 calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase (hG6PD), D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase (hG6PD)	Homo sapiens	D-glucose 6-phosphatecosubstrate NADP+ (varied)	57.5	—	—	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase (hG6PD), D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase (hG6PD)	Homo sapiens	NADP+	56.9	0.0175	3.25 × 10³ calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase (hG6PD), NADP+
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	D-glucose-6-phosphate	—	1.39	—	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), D-glucose-6-phosphate
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	D-glucose-6-phosphatekcat: the paper does not say per subunit or per oligomer	8.063 × 10⁴	—	5.8 × 10⁴	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), D-glucose-6-phosphate
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	erythrose-4-phosphate	—	2.72	—	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), erythrose-4-phosphate
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	erythrose-4-phosphatekcat: the paper does not say per subunit or per oligomer	37,084	—	1.36 × 10⁴	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), erythrose-4-phosphate
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	NAD+	—	5.64	—	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), NAD+
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	NAD+kcat: the paper does not say per subunit or per oligomer	14,374	—	2.55 × 10³	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), NAD+
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	NADP+	—	0.63	—	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), NADP+
glucose-6-phosphate dehydrogenase (ScrG6PDH)	Streptococcus cristatus	NADP+kcat: the paper does not say per subunit or per oligomer	84,091	—	1.33 × 10⁵	pH 8, 37 °C	PMID 42650878	Open record: glucose-6-phosphate dehydrogenase (ScrG6PDH), NADP+
glucose-6-phosphate dehydrogenase (TcG6PDH_L)	Trypanosoma cruzi	glucose 6-phosphate	62	0.077	800	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L), glucose 6-phosphate
glucose-6-phosphate dehydrogenase (TcG6PDH_L)	Trypanosoma cruzi	NADP+	52	0.016	3.2 × 10³	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L), NADP+
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant K83A	Trypanosoma cruzi	glucose 6-phosphate	2.8	0.537	5	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant K83A, glucose 6-phosphate
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant K83A	Trypanosoma cruzi	NADP+	3	0.021	140	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant K83A, NADP+
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant K84A	Trypanosoma cruzi	glucose 6-phosphate	24.6	0.618	40	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant K84A, glucose 6-phosphate
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant K84A	Trypanosoma cruzi	NADP+	58	0.017	3.4 × 10³	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant K84A, NADP+
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant L80G	Trypanosoma cruzi	glucose 6-phosphate	2	0.074	27	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant L80G, glucose 6-phosphate
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant L80G	Trypanosoma cruzi	NADP+	2.7	0.075	36	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant L80G, NADP+
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant R408A	Trypanosoma cruzi	glucose 6-phosphate	15	0.168	89	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant R408A, glucose 6-phosphate
glucose-6-phosphate dehydrogenase (TcG6PDH_L)variant R408A	Trypanosoma cruzi	NADP+	19	0.017	1.1 × 10³	pH 7.5, 25 °C	PMID 26999093	Open record: glucose-6-phosphate dehydrogenase (TcG6PDH_L) variant R408A, NADP+
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	2-deoxy-D-glucose 6-phosphatecosubstrate NADP+ (at Km)	7.3	2.67	2.7 calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), 2-deoxy-D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	2-deoxy-D-glucose 6-phosphatecosubstrate NADP+ (varied)	4.69	—	—	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), 2-deoxy-D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	D-glucose 6-phosphatecosubstrate NADP+ (200 uM)	8.6	0.0192	450 calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	D-glucose 6-phosphatecosubstrate NADP+ (varied)	6.2	0.0159	390 calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	glucose-6-phosphateLOPAC and Spectrum	—	0.0145	—		PMID 22496096	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), glucose-6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	glucose-6-phosphateChemBridge	—	0.0125	—		PMID 22496096	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), glucose-6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	NADP+cosubstrate G6P (200 uM)	8.2	0.0065	1.3 × 10³ calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), NADP+
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	NADP+cosubstrate G6P (varied)	—	0.0081	—	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), NADP+
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	nicotinamide adenine dinucleotide phosphate (oxidized)LOPAC and Spectrum	—	0.01	—		PMID 22496096	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho)	Plasmodium falciparum	nicotinamide adenine dinucleotide phosphate (oxidized)ChemBridge	—	0.0086	—		PMID 22496096	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho), nicotinamide adenine dinucleotide phosphate (oxidized)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, G6PD part (G6PDPfGluPho)	Plasmodium falciparum	D-glucose 6-phosphate	6.3	0.0332	190 calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, G6PD part (G6PDPfGluPho), D-glucose 6-phosphate
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, G6PD part (G6PDPfGluPho)	Plasmodium falciparum	NADP+	6.3	0.0061	1.0 × 10³ calc.	pH 8, 25 °C	PMID 21443518	Open record: glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, G6PD part (G6PDPfGluPho), NADP+
plastid Glc6PDH	Hordeum vulgare	glucose-6-phosphate10 mM MgCl2; 0.15 mM NADP+ (standard assay)	—	0.98	—	pH 8	PMID 11525521	Open record: plastid Glc6PDH, glucose-6-phosphate
plastid Glc6PDH	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+; with 2 mM ATP plus Mg2+ (10 mM)	—	0.84	—	pH 8	PMID 11525521	Open record: plastid Glc6PDH, glucose-6-phosphate
plastid Glc6PDH	Hordeum vulgare	glucose-6-phosphate0.15 mM NADP+	—	1	—	pH 8	PMID 11525521	Open record: plastid Glc6PDH, glucose-6-phosphate
plastid Glc6PDH	Hordeum vulgare	NADP+	—	0.014	—	pH 8	PMID 11525521	Open record: plastid Glc6PDH, NADP+