EC 1.11.1.9: glutathione peroxidase
OxidoreductasesOpen in Browse
CatLog read 42 records for EC 1.11.1.9 from 6 papers, for 4 organisms. Names in these papers: glutathione peroxidase (GPx-1 + GPx-4 activity), glutaredoxin 1 (yGrx1), Grx1 (glutaredoxin 1), Grx2 (glutaredoxin 2) and 7 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 31 records for EC 1.11.1.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.11.1.9 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondria | Rattus norvegicus | 11 |
| Role of yeast glutaredoxins as glutathione S-transferases | Saccharomyces cerevisiae | 10 |
| Structural aspects of the distinct biochemical properties of glutaredoxin 1 and glutaredoxin 2 from Saccharomyces cerevisiae | Saccharomyces cerevisiae | 9 |
| A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster | Drosophila melanogaster | 8 |
| Cuprous oxidase activity of yeast Fet3p and human ceruloplasmin: implication for function | Homo sapiens | 2 |
| A robust metallo-oxidase from the hyperthermophilic bacterium Aquifex aeolicus | Homo sapiens | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| ceruloplasmin | Homo sapiens | copper(1+) | 0.25 | 0.033 | 7.6 calc. | pH 3.5, 40 °C | PMID 17451433 | Open record: ceruloplasmin, copper(1+) |
| ceruloplasmin | Homo sapiens | iron(2+) | 0.13 | 0.028 | 4.8 calc. | pH 5, 40 °C | PMID 17451433 | Open record: ceruloplasmin, iron(2+) |
| ceruloplasmin (hCp) | Homo sapiens | copper(1+) | 0.375 | 0.0368 | 10.2 calc. | pH 5 | PMID 14623105 | Open record: ceruloplasmin (hCp), copper(1+) |
| ceruloplasmin (hCp) | Homo sapiens | iron(2+) | 0.505 | 0.0083 | 61 calc. | pH 5 | PMID 14623105 | Open record: ceruloplasmin (hCp), iron(2+) |
| DmGSTD11b-11b | Drosophila melanogaster | 1-chloro-2,4-dinitrobenzene | 111 | 2.52 | 44.1 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTD11b-11b, 1-chloro-2,4-dinitrobenzene |
| DmGSTD11b-11b | Drosophila melanogaster | glutathione | — | 0.99 | 110 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTD11b-11b, glutathione |
| DmGSTE6-6 | Drosophila melanogaster | 1-chloro-2,4-dinitrobenzene | 86.8 | 0.13 | 660 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTE6-6, 1-chloro-2,4-dinitrobenzene |
| DmGSTE6-6 | Drosophila melanogaster | glutathione | — | 1.71 | 50.8 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTE6-6, glutathione |
| DmGSTE7-7 | Drosophila melanogaster | 1-chloro-2,4-dinitrobenzene | 34.7 | 0.2 | 170 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTE7-7, 1-chloro-2,4-dinitrobenzene |
| DmGSTE7-7 | Drosophila melanogaster | glutathione | — | 0.78 | 45 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTE7-7, glutathione |
| DmGSTT2-2 | Drosophila melanogaster | 1-chloro-2,4-dinitrobenzene | 47.6 | 1.05 | 45.4 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTT2-2, 1-chloro-2,4-dinitrobenzene |
| DmGSTT2-2 | Drosophila melanogaster | glutathione | — | 10.7 | 4.45 | pH 6.5, 25 °C | PMID 22082028 | Open record: DmGSTT2-2, glutathione |
| glutaredoxin 1 (yGrx1) | Saccharomyces cerevisiae | glutathione | 17.1 | 6.2 | 2.75 | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 1 (yGrx1), glutathione |
| glutaredoxin 1 (yGrx1) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 0.5 mM | 1.3 | 0.12 | 11 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 1 (yGrx1), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 1 (yGrx1) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 1.0 mM | 2.2 | 0.12 | 18 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 1 (yGrx1), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 1 (yGrx1) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 1.5 mM | 3.5 | 0.14 | 25 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 1 (yGrx1), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 1 (yGrx1) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 2.0 mM | 4.2 | 0.13 | 32 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 1 (yGrx1), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 2 (yGrx2) | Saccharomyces cerevisiae | glutathione | 129 | 0.9 | 143 | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 2 (yGrx2), glutathione |
| glutaredoxin 2 (yGrx2) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 0.5 mM | 47 | 0.9 | 52 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 2 (yGrx2), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 2 (yGrx2) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 1.0 mM | 66 | 0.7 | 94 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 2 (yGrx2), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutaredoxin 2 (yGrx2) | Saccharomyces cerevisiae | glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED)fixed GSH 1.5 mM | 85 | 0.6 | 140 calc. | pH 7.4, 30 °C | PMID 18992757 | Open record: glutaredoxin 2 (yGrx2), glutathionylated beta-mercaptoethanol (mixed disulfide of GSH and HED) |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | cumene hydroperoxidemitochondria isolated from AS-30D rat hepatoma cells | — | 0.481 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), cumene hydroperoxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | cumene hydroperoxiderat liver mitochondria | — | 0.251 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), cumene hydroperoxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | cumene hydroperoxiderat heart mitochondria | — | 0.438 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), cumene hydroperoxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | hydrogen peroxideliver | — | 0.055 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), hydrogen peroxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | hydrogen peroxideheart | — | 0.0222 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), hydrogen peroxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | reduced glutathionemitochondria isolated from AS-30D rat hepatoma cells | — | 10.4 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), reduced glutathione |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | reduced glutathionerat liver mitochondria | — | 10.5 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), reduced glutathione |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | reduced glutathionerat heart mitochondria | — | 7.5 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), reduced glutathione |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | tert-butyl hydroperoxidemitochondria isolated from AS-30D rat hepatoma cells | — | 0.256 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), tert-butyl hydroperoxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | tert-butyl hydroperoxiderat liver mitochondria | — | 0.326 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), tert-butyl hydroperoxide |
| glutathione peroxidase (GPx-1 + GPx-4 activity) | Rattus norvegicus | tert-butyl hydroperoxiderat heart mitochondria | — | 0.553 | — | pH 7.2, 37 °C | PMID 30053395 | Open record: glutathione peroxidase (GPx-1 + GPx-4 activity), tert-butyl hydroperoxide |
| Grx1 (glutaredoxin 1) | Saccharomyces cerevisiae | 1,2-dichloro-4-nitrobenzene | 0.22 | 1.3 | 0.17 | pH 6.5 | PMID 12684511 | Open record: Grx1 (glutaredoxin 1), 1,2-dichloro-4-nitrobenzene |
| Grx1 (glutaredoxin 1) | Saccharomyces cerevisiae | 1-chloro-2,4-dinitrobenzene | 13.1 | 4.2 | 3.1 | pH 6.5 | PMID 12684511 | Open record: Grx1 (glutaredoxin 1), 1-chloro-2,4-dinitrobenzene |
| Grx1 (glutaredoxin 1) | Saccharomyces cerevisiae | cumene hydroperoxide | 14.3 | 0.52 | 28 | PMID 12684511 | Open record: Grx1 (glutaredoxin 1), cumene hydroperoxide | |
| Grx1 (glutaredoxin 1) | Saccharomyces cerevisiae | hydrogen peroxide | 47.1 | 0.88 | 53 | PMID 12684511 | Open record: Grx1 (glutaredoxin 1), hydrogen peroxide | |
| Grx1 (glutaredoxin 1) | Saccharomyces cerevisiae | tert-butyl hydroperoxide | 2.9 | 0.37 | 7.8 | PMID 12684511 | Open record: Grx1 (glutaredoxin 1), tert-butyl hydroperoxide | |
| Grx2 (glutaredoxin 2) | Saccharomyces cerevisiae | 1,2-dichloro-4-nitrobenzene | 1.1 | 0.27 | 4.2 | pH 6.5 | PMID 12684511 | Open record: Grx2 (glutaredoxin 2), 1,2-dichloro-4-nitrobenzene |
| Grx2 (glutaredoxin 2) | Saccharomyces cerevisiae | 1-chloro-2,4-dinitrobenzene | 0.99 | 0.17 | 5.9 | pH 6.5 | PMID 12684511 | Open record: Grx2 (glutaredoxin 2), 1-chloro-2,4-dinitrobenzene |
| Grx2 (glutaredoxin 2) | Saccharomyces cerevisiae | cumene hydroperoxide | 12.9 | 0.87 | 15 | PMID 12684511 | Open record: Grx2 (glutaredoxin 2), cumene hydroperoxide | |
| Grx2 (glutaredoxin 2) | Saccharomyces cerevisiae | hydrogen peroxide | 52.9 | 2 | 26 | PMID 12684511 | Open record: Grx2 (glutaredoxin 2), hydrogen peroxide | |
| Grx2 (glutaredoxin 2) | Saccharomyces cerevisiae | tert-butyl hydroperoxide | 14.3 | 2.2 | 6.5 | PMID 12684511 | Open record: Grx2 (glutaredoxin 2), tert-butyl hydroperoxide |