EC 1.14.11.2: procollagen-proline 4-dioxygenase
OxidoreductasesOpen in Browse
CatLog read 53 records for EC 1.14.11.2 from 3 papers, for 3 organisms. Names in these papers: prolyl 4-hydroxylase Cr-P4H-1, HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), prolyl 4-hydroxylase At-P4H-1.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 47 records for EC 1.14.11.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.11.2 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif | Chlamydomonas reinhardtii | 19 |
| Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription… | Arabidopsis thaliana | 17 |
| Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor | Homo sapiens | 17 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | 2-oxoglutarate | — | 0.06 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), 2-oxoglutarate |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | ascorbate | — | 0.17 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), ascorbate |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DALDLEMLAPYISMDDDFQL | — | 0.007 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DALDLEMLAPYISMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DALTLLAPAAGDTIISLFG | — | 0.38 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DALTLLAPAAGDTIISLFG |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPAIPMDDDFQL | — | 0.02 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPAIPMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPGIPMDDDFQL | — | 0.02 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPGIPMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPYIPMD | — | 0.1 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPYIPMD |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPYIPMDD | — | 0.1 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPYIPMDD |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPYIPMDDDF | — | 0.07 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPYIPMDDDF |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPYIPMDDDFQL | — | 0.008 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPYIPMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLDLEMLAPYIPMDDDFQLRSFDQ | — | 0.008 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLDLEMLAPYIPMDDDFQLRSFDQ |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | DLEMLAPYIPMDDDFQL | — | 0.014 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), DLEMLAPYIPMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | EEPDLSCLAPFVDTYDMMQM | — | 0.1 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), EEPDLSCLAPFVDTYDMMQM |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | ELDLETLAPYIPMDGEDFQ | — | 0.03 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), ELDLETLAPYIPMDGEDFQ |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | EMLAPYIPMDDDFQL | — | 0.08 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), EMLAPYIPMDDDFQL |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | EPEELAQLAPTPGDAIISLD | — | 0.1 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), EPEELAQLAPTPGDAIISLD |
| HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1) | Homo sapiens | O2 | — | 0.23 | — | pH 7.8, 37 °C | PMID 12788921 | Open record: HIF-P4H-1 (HIF prolyl 4-hydroxylase isoenzyme 1), O2 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Ala-Pro-Gly)5 | — | 0.1 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Ala-Pro-Gly)5 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Ala-Thr-Pro-Pro-Pro-Val)3 | — | 0.02 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Ala-Thr-Pro-Pro-Pro-Val)3 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Ala-Gly)5 | — | 0.28 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Ala-Gly)5 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Ala-Pro-Lys)10 | — | 0.002 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Ala-Pro-Lys)10 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Ala-Pro-Lys)3 | — | 0.09 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Ala-Pro-Lys)3 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Glu-Pro-Pro-Ala)5 | — | 0.004 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Glu-Pro-Pro-Ala)5 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Pro-Gly)10 | — | 0.06 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Pro-Gly)10 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Pro-Pro-Gly)5 | — | 0.12 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Pro-Pro-Gly)5 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | (Ser-Pro-Lys-Pro-Pro)5 | — | 0.02 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, (Ser-Pro-Lys-Pro-Pro)5 |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | 2-oxoglutarate | — | 0.13 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, 2-oxoglutarate |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | ascorbate | — | 0.3 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, ascorbate |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | Asp-Ala-Leu-Thr-Leu-Leu-Ala-Pro-Ala-Ala-Gly-Asp-Thr-Ile-Ile-Ser-Leu-Phe-Gly | — | 0.1 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, Asp-Ala-Leu-Thr-Leu-Leu-Ala-Pro-Ala-Ala-Gly-Asp-Thr-Ile-Ile-Ser-Leu-Phe-Gly |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu | — | 0.05 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | poly(L-proline) | — | 0.002 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, poly(L-proline) |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | poly(L-proline) | — | 2 × 10⁻⁴ | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, poly(L-proline) |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | Ser-Pro-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Pro-Val | — | 0.01 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, Ser-Pro-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Pro-Val |
| prolyl 4-hydroxylase At-P4H-1 | Arabidopsis thaliana | Ser-Pro-Pro-Pro-Val-Tyr-Lys-Ser-Pro-Pro-Pro-Pro-Val-Lys-His-Tyr-Ser-Pro-Pro-Pro-Val | — | 0.04 | — | 30 °C | PMID 11976332 | Open record: prolyl 4-hydroxylase At-P4H-1, Ser-Pro-Pro-Pro-Val-Tyr-Lys-Ser-Pro-Pro-Pro-Pro-Val-Lys-His-Tyr-Ser-Pro-Pro-Pro-Val |
| prolyl 4-hydroxylase Cr-P4H-1 | Chlamydomonas reinhardtii | (Pro-Pro-Gly)10 collagen-like peptide | 7 | 0.93 | 7.5 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1, (Pro-Pro-Gly)10 collagen-like peptide | |
| prolyl 4-hydroxylase Cr-P4H-1 | Chlamydomonas reinhardtii | poly(L-proline) | 30 | 0.29 | 100 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1 | Chlamydomonas reinhardtii | Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | 19 | 0.38 | 50 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1, Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | |
| prolyl 4-hydroxylase Cr-P4H-1variant D149A | Chlamydomonas reinhardtii | poly(L-proline) | 2 | 0.63 | 3.2 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant D149A, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant D149N | Chlamydomonas reinhardtii | poly(L-proline) | 6 | 0.56 | 11 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant D149N, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant D81A | Chlamydomonas reinhardtii | poly(L-proline) | 7 | 0.88 | 8.0 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant D81A, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant G85A | Chlamydomonas reinhardtii | poly(L-proline) | 4 | 0.94 | 4.3 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant G85A, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant N152A | Chlamydomonas reinhardtii | poly(L-proline) | 2 | 1.59 | 1.3 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant N152A, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T | Chlamydomonas reinhardtii | (Pro-Pro-Gly)10 collagen-like peptide | 9 | 0.83 | 11 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T, (Pro-Pro-Gly)10 collagen-like peptide | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T | Chlamydomonas reinhardtii | poly(L-proline) | 20 | 0.11 | 180 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T | Chlamydomonas reinhardtii | Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | 14 | 0.19 | 74 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T, Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T/S87L | Chlamydomonas reinhardtii | (Pro-Pro-Gly)10 collagen-like peptide | 5 | 1.27 | 3.9 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T/S87L, (Pro-Pro-Gly)10 collagen-like peptide | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T/S87L | Chlamydomonas reinhardtii | poly(L-proline) | 4 | 0.35 | 11 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T/S87L, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant S78T/S87L | Chlamydomonas reinhardtii | Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | 6 | 0.14 | 43 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S78T/S87L, Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | |
| prolyl 4-hydroxylase Cr-P4H-1variant S84A | Chlamydomonas reinhardtii | poly(L-proline) | 2 | 0.77 | 2.6 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S84A, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant S87L | Chlamydomonas reinhardtii | (Pro-Pro-Gly)10 collagen-like peptide | 6 | 1.05 | 5.7 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S87L, (Pro-Pro-Gly)10 collagen-like peptide | |
| prolyl 4-hydroxylase Cr-P4H-1variant S87L | Chlamydomonas reinhardtii | poly(L-proline) | 8 | 0.26 | 31 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S87L, poly(L-proline) | |
| prolyl 4-hydroxylase Cr-P4H-1variant S87L | Chlamydomonas reinhardtii | Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | 18 | 0.78 | 23 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant S87L, Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro-Ser-Pro | |
| prolyl 4-hydroxylase Cr-P4H-1variant Y140F | Chlamydomonas reinhardtii | poly(L-proline) | 3 | 0.34 | 8.8 calc. | PMID 19553701 | Open record: prolyl 4-hydroxylase Cr-P4H-1 variant Y140F, poly(L-proline) |