EC 1.14.13.181: 13-deoxydaunorubicin hydroxylase
OxidoreductasesOpen in Browse
CatLog read 4 records for EC 1.14.13.181 from 1 paper, for 1 organism. Names in these papers: DoxA (cytochrome P-450 monooxygenase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Purification, properties, and characterization of recombinant Streptomyces sp. strain C5 DoxA, a cytochrome P-450 catalyzing multiple steps in doxorubicin biosynthesis | Streptomyces sp. | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| DoxA (cytochrome P-450 monooxygenase) | Streptomyces sp. | 13-deoxydaunorubicin | 0.024 | 0.0011 | 22 | pH 7.5, 30 °C | PMID 9864343 | Open record: DoxA (cytochrome P-450 monooxygenase), 13-deoxydaunorubicin |
| DoxA (cytochrome P-450 monooxygenase) | Streptomyces sp. | 13-dihydrocarminomycin | 2.6 × 10⁻⁴ | 0.0025 | 0.28 | pH 7.5, 30 °C | PMID 9864343 | Open record: DoxA (cytochrome P-450 monooxygenase), 13-dihydrocarminomycin |
| DoxA (cytochrome P-450 monooxygenase) | Streptomyces sp. | 13-dihydrodaunorubicin | 0.63 | 0.0046 | 14 | pH 7.5, 30 °C | PMID 9864343 | Open record: DoxA (cytochrome P-450 monooxygenase), 13-dihydrodaunorubicin |
| DoxA (cytochrome P-450 monooxygenase) | Streptomyces sp. | daunorubicin | 1.2 × 10⁻⁴ | 9 × 10⁻⁴ | 0.13 | pH 7.5, 30 °C | PMID 9864343 | Open record: DoxA (cytochrome P-450 monooxygenase), daunorubicin |