EC 1.14.13.39: nitric-oxide synthase (NADPH)
OxidoreductasesOpen in Browse
CatLog read 23 records for EC 1.14.13.39 from 2 papers, for 2 organisms. Names in these papers: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain, human neuronal nitric oxide synthase (full-length), human nNOS FAD-FMN domain, human nNOS FAD-NADPH domain.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 56 records for EC 1.14.13.39 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.13.39 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Human neuronal nitric oxide synthase can catalyze one-electron reduction of adriamycin: role of flavin domain | Homo sapiens | 15 |
| Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395 | Rattus norvegicus | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | 2-methyl-1,4-naphthoquinonewithout calmodulin/Ca2+ | 6.55 | 0.014 | 470 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), 2-methyl-1,4-naphthoquinone |
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | 2-methyl-1,4-naphthoquinonewith 3 μM calmodulin and 1 mM CaCl2 | 94.37 | 0.011 | 8.6 × 10³ calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), 2-methyl-1,4-naphthoquinone |
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | adriamycin (doxorubicin)without calmodulin/Ca2+ | 5.3 | 0.021 | 250 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), adriamycin (doxorubicin) |
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | adriamycin (doxorubicin)with 3 μM calmodulin and 1 mM CaCl2 | 95.48 | 0.043 | 2.2 × 10³ calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), adriamycin (doxorubicin) |
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | mitomycin cwithout calmodulin/Ca2+ | 0.62 | 0.0073 | 84 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), mitomycin c |
| human neuronal nitric oxide synthase (full-length) | Homo sapiens | mitomycin cwith 3 μM calmodulin and 1 mM CaCl2 | 14.18 | 0.013 | 1.1 × 10³ calc. | pH 7, 25 °C | PMID 15196992 | Open record: human neuronal nitric oxide synthase (full-length), mitomycin c |
| human nNOS FAD-FMN domain | Homo sapiens | 2-methyl-1,4-naphthoquinonewithout calmodulin/Ca2+ | 9.42 | 0.01 | 940 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, 2-methyl-1,4-naphthoquinone |
| human nNOS FAD-FMN domain | Homo sapiens | 2-methyl-1,4-naphthoquinonewith 3 μM calmodulin and 1 mM CaCl2 | 87 | 0.01 | 8.7 × 10³ calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, 2-methyl-1,4-naphthoquinone |
| human nNOS FAD-FMN domain | Homo sapiens | adriamycin (doxorubicin)without calmodulin/Ca2+ | 4.8 | 0.012 | 400 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, adriamycin (doxorubicin) |
| human nNOS FAD-FMN domain | Homo sapiens | adriamycin (doxorubicin)with 3 μM calmodulin and 1 mM CaCl2 | 93.67 | 0.078 | 1.2 × 10³ calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, adriamycin (doxorubicin) |
| human nNOS FAD-FMN domain | Homo sapiens | mitomycin cwithout calmodulin/Ca2+ | 2.02 | 0.015 | 130 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, mitomycin c |
| human nNOS FAD-FMN domain | Homo sapiens | mitomycin cwith 3 μM calmodulin and 1 mM CaCl2 | 24.62 | 0.055 | 450 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-FMN domain, mitomycin c |
| human nNOS FAD-NADPH domain | Homo sapiens | 2-methyl-1,4-naphthoquinone | 7.97 | 0.041 | 190 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-NADPH domain, 2-methyl-1,4-naphthoquinone |
| human nNOS FAD-NADPH domain | Homo sapiens | adriamycin (doxorubicin) | 4.9 | 0.05 | 98 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-NADPH domain, adriamycin (doxorubicin) |
| human nNOS FAD-NADPH domain | Homo sapiens | mitomycin c | 0.63 | 0.028 | 23 calc. | pH 7, 25 °C | PMID 15196992 | Open record: human nNOS FAD-NADPH domain, mitomycin c |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domain | Rattus norvegicus | NADH | 44.1 | 5.89 | 7.5 | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain, NADH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domain | Rattus norvegicus | NADPH | 161.6 | 0.0282 | 5.7 × 10³ | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain, NADPH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395A | Rattus norvegicus | NADH | 259.8 | 3.25 | 79.9 | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395A, NADH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395A | Rattus norvegicus | NADPH | 209.8 | 0.0835 | 2.5 × 10³ | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395A, NADPH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395S | Rattus norvegicus | NADH | 114.8 | 1.83 | 62.7 | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395S, NADH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395S | Rattus norvegicus | NADPH | 50.8 | 0.0229 | 2.2 × 10³ | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395S, NADPH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395W | Rattus norvegicus | NADH | 34.6 | 3.55 | 9.7 | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395W, NADH |
| neuronal nitric oxide synthase (nNOS) FAD/NADPH domainvariant F1395W | Rattus norvegicus | NADPH | 113.5 | 0.0154 | 7.4 × 10³ | pH 7.4, 25 °C | PMID 15182370 | Open record: neuronal nitric oxide synthase (nNOS) FAD/NADPH domain variant F1395W, NADPH |