EC 1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase
OxidoreductasesOpen in Browse
CatLog read 5 records for EC 1.14.14.12 from 1 paper, for 1 organism. Names in these papers: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism | Mycobacterium tuberculosis | 5 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB) | Mycobacterium tuberculosis | 3,17-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9-one | 0.24 | 0.35 | 0.7 | pH 7, 25 °C | PMID 20448045 | Open record: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB), 3,17-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9-one |
| HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB) | Mycobacterium tuberculosis | 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dioneHsaB reconstituted with FAD | 0.075 | 0.097 | 0.77 | pH 7, 25 °C | PMID 20448045 | Open record: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB), 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione |
| HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB) | Mycobacterium tuberculosis | 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dioneHsaB reconstituted with FMN | 0.2 | 0.2 | 1 | pH 7, 25 °C | PMID 20448045 | Open record: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB), 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione |
| HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB) | Mycobacterium tuberculosis | 3-hydroxybiphenyl | 0.11 | 1.44 | 0.08 | pH 7, 25 °C | PMID 20448045 | Open record: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB), 3-hydroxybiphenyl |
| HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB) | Mycobacterium tuberculosis | oxygen | 0.031 | 0.1 | 0.32 | pH 7, 25 °C | PMID 20448045 | Open record: HsaAB (3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase; oxygenase HsaA + reductase HsaB), oxygen |