CatLogenzyme kinetics catalog

EC 1.14.14.197: progesterone 11alpha-monooxygenase

OxidoreductasesOpen in Browse

CatLog read 15 records for EC 1.14.14.197 from 1 paper, for 0 organisms. Names in these papers: CYP106A2.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

PaperOrganismsRecords
Changing the regioselectivity of a P450 from C15 to C11 hydroxylation of progesterone—15

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
CYP106A2—progesterone—0.203—PMID 22532270Open
CYP106A2variant A106T/A395I—progesterone—0.091—PMID 22532270Open
CYP106A2variant A106T/A395I/R409L—progesterone—0.046—PMID 22532270Open
CYP106A2variant A106T/A395W/G379K/R409L—progesterone—0.048—PMID 22532270Open
CYP106A2variant A243V/A395I—progesterone—0.02—PMID 22532270Open
CYP106A2variant A243V/A395W/G397K—progesterone—0.026—PMID 22532270Open
CYP106A2variant A395I—progesterone—0.032—PMID 22532270Open
CYP106A2variant A395W/G397K—progesterone—0.055—PMID 22532270Open
CYP106A2variant D217V/A395I—progesterone—0.028—PMID 22532270Open
CYP106A2variant M155I/F165L/A395I—progesterone—0.032—PMID 22532270Open
CYP106A2variant T247V/A395I—progesterone—0.038—PMID 22532270Open
CYP106A2variant T247W/A395W/G379K—progesterone—0.039—PMID 22532270Open
CYP106A2variant T248V/A395I—progesterone—0.052—PMID 22532270Open
CYP106A2variant T89N/A106T/A395I/R409L—progesterone—0.109—PMID 22532270Open
CYP106A2variant T89N/A395I—progesterone—0.084—PMID 22532270Open