EC 1.14.99.7: squalene monooxygenase

CatLog read 26 records for EC 1.14.99.7 from 1 paper, for 1 organism. Names in these papers: squalene epoxidase.

EC 1.14.99.7 is no longer current; BRENDA: “transferred to EC 1.14.13.132”.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

Papers with records for EC 1.14.99.7
Paper	Organisms	Records
Site-directed mutagenesis of conserved aromatic residues in rat squalene epoxidase	Rattus norvegicus	26

Records

Records for EC 1.14.99.7 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
squalene epoxidase	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.0075	0.00425	1.75	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase, (RS)-2,3-oxidosqualene
squalene epoxidase	Rattus norvegicus	squalene	0.0757	0.00987	7.67	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase, squalene
squalene epoxidasevariant F223A	Rattus norvegicus	squalene	0.0067	6.9 × 10⁻⁴	9.67	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F223A, squalene
squalene epoxidasevariant F228A	Rattus norvegicus	squalene	1.05 × 10⁻⁴	0.00191	0.05	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F228A, squalene
squalene epoxidasevariant F287A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.0053	0.00259	2.03	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F287A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant F287A	Rattus norvegicus	squalene	0.0295	0.00966	3.05	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F287A, squalene
squalene epoxidasevariant F305A	Rattus norvegicus	(RS)-2,3-oxidosqualene	8.3 × 10⁻⁴	0.00177	0.5	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F305A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant F305A	Rattus norvegicus	squalene	0.069	0.0255	2.7	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F305A, squalene
squalene epoxidasevariant F476A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.0037	0.0136	0.27	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F476A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant F476A	Rattus norvegicus	squalene	0.0985	0.0223	4.42	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F476A, squalene
squalene epoxidasevariant F491A	Rattus norvegicus	squalene	0.0523	0.0246	2.13	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F491A, squalene
squalene epoxidasevariant F522A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.004	0.0225	0.18	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F522A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant F522A	Rattus norvegicus	squalene	0.0117	0.00414	2.82	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F522A, squalene
squalene epoxidasevariant F523A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.0052	0.0103	0.52	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F523A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant F523A	Rattus norvegicus	squalene	0.0398	0.01136	3.5	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant F523A, squalene
squalene epoxidasevariant Y194A	Rattus norvegicus	(RS)-2,3-oxidosqualene	6.7 × 10⁻⁴	0.00219	0.28	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y194A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant Y194A	Rattus norvegicus	squalene	0.0052	0.00379	1.37	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y194A, squalene
squalene epoxidasevariant Y209A	Rattus norvegicus	squalene	9.5 × 10⁻⁵	9.7 × 10⁻⁴	0.1	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y209A, squalene
squalene epoxidasevariant Y334A	Rattus norvegicus	(RS)-2,3-oxidosqualene	6.7 × 10⁻⁴	0.0111	0.05	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y334A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant Y334A	Rattus norvegicus	squalene	0.0445	0.0128	3.48	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y334A, squalene
squalene epoxidasevariant Y473A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.012	0.0035	3.42	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y473A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant Y473A	Rattus norvegicus	squalene	0.0435	0.0301	1.45	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y473A, squalene
squalene epoxidasevariant Y493A	Rattus norvegicus	(RS)-2,3-oxidosqualene	1.7 × 10⁻⁴	1.7 × 10⁻⁴	1.1	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y493A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant Y493A	Rattus norvegicus	squalene	0.0183	0.0106	1.73	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y493A, squalene
squalene epoxidasevariant Y528A	Rattus norvegicus	(RS)-2,3-oxidosqualene	0.0133	0.0104	1.28	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y528A, (RS)-2,3-oxidosqualene
squalene epoxidasevariant Y528A	Rattus norvegicus	squalene	0.1628	0.0453	3.6	pH 7.4, 37 °C	PMID 17112472	Open record: squalene epoxidase variant Y528A, squalene