EC 1.2.1.16: succinate-semialdehyde dehydrogenase [NAD(P)+]
OxidoreductasesOpen in Browse
CatLog read 22 records for EC 1.2.1.16 from 3 papers, for 3 organisms. Names in these papers: GabD (succinate semialdehyde dehydrogenase, SSADHase), succinic semialdehyde dehydrogenase SSADH-II, succinic semialdehyde dehydrogenase 1 (GabD1).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 48 records for EC 1.2.1.16 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.2.1.16 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus | Sulfolobus solfataricus | 9 |
| New pieces to the carbon metabolism puzzle of Nitrosomonas europaea: Kinetic characterization of glyceraldehyde-3 phosphate and succinate semialdehyde dehydrogenases | Nitrosomonas europaea | 9 |
| On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis | Mycobacterium tuberculosis | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | D-glyceraldehyde 3-phosphatecosubstrate NADP^+ | 0.0133 | 1.9 | 0.007 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), D-glyceraldehyde 3-phosphate |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | D-glyceraldehyde 3-phosphatecosubstrate NAD^+ | 0.017 | 2.2 | 0.008 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), D-glyceraldehyde 3-phosphate |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | L-glyceraldehyde 3-phosphate | 0.0067 | 3 | 0.0022 calc. | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), L-glyceraldehyde 3-phosphate |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | NAD^+cosubstrate SSA | 0.45 | 1.12 | 0.4 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), NAD^+ |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | NAD^+cosubstrate D-Ga3P | 0.017 | 0.4 | 0.05 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), NAD^+ |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | NADP^+cosubstrate SSA | 0.62 | 0.04 | 15 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), NADP^+ |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | NADP^+cosubstrate D-Ga3P | 0.0133 | 0.23 | 0.056 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), NADP^+ |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | succinate semialdehydecosubstrate NADP^+ | 0.58 | 0.03 | 25 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), succinate semialdehyde |
| GabD (succinate semialdehyde dehydrogenase, SSADHase) | Nitrosomonas europaea | succinate semialdehydecosubstrate NAD^+ | 0.48 | 0.07 | 7 | pH 8.5, 30 °C | PMID 30690134 | Open record: GabD (succinate semialdehyde dehydrogenase, SSADHase), succinate semialdehyde |
| succinic semialdehyde dehydrogenase 1 (GabD1) | Mycobacterium tuberculosis | NADP+no Mg2+ added | 1.3 | 0.0613 | 210 | pH 7.5, 37 °C | PMID 21303655 | Open record: succinic semialdehyde dehydrogenase 1 (GabD1), NADP+ |
| succinic semialdehyde dehydrogenase 1 (GabD1) | Mycobacterium tuberculosis | NADP+10 mM MgCl2 | 2.7 | 0.0092 | 290 | pH 7.5, 37 °C | PMID 21303655 | Open record: succinic semialdehyde dehydrogenase 1 (GabD1), NADP+ |
| succinic semialdehyde dehydrogenase 1 (GabD1) | Mycobacterium tuberculosis | succinic semialdehydeno Mg2+ added | 1.9 | 0.0133 | 140 | pH 7.5, 37 °C | PMID 21303655 | Open record: succinic semialdehyde dehydrogenase 1 (GabD1), succinic semialdehyde |
| succinic semialdehyde dehydrogenase 1 (GabD1) | Mycobacterium tuberculosis | succinic semialdehyde10 mM MgCl2; partial substrate inhibition | 4.7 | 0.003 | 1.6 × 10³ | pH 7.5, 37 °C | PMID 21303655 | Open record: succinic semialdehyde dehydrogenase 1 (GabD1), succinic semialdehyde |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | alpha-ketoglutaric semialdehyde (2,5-dioxopentanoate)NADPH formation at 340 nm; 1 mM NADP+; cosubstrate NADP+ | 21.2 | 0.2 | 134.1 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, alpha-ketoglutaric semialdehyde (2,5-dioxopentanoate) |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | alpha-ketoglutaric semialdehyde (2,5-dioxopentanoate)NADH formation at 340 nm; 5 mM NAD+; cosubstrate NAD+ | 27.3 | 0.1 | 215.3 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, alpha-ketoglutaric semialdehyde (2,5-dioxopentanoate) |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | D,L-glyceraldehyde | 3 | 114 | 0.03 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, D,L-glyceraldehyde |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | D,L-glyceraldehyde 3-phosphate | 2.8 | 23.3 | 0.1 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, D,L-glyceraldehyde 3-phosphate |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | glycolaldehyde | 1.8 | 21.2 | 0.1 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, glycolaldehyde |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | nicotinamide adenine dinucleotide (oxidized) | 136.3 | 11.1 | 12.3 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | nicotinamide adenine dinucleotide phosphate (oxidized) | 16.5 | 0.01 | 3066 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, nicotinamide adenine dinucleotide phosphate (oxidized) |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | succinic semialdehydeNADPH formation at 340 nm; 1 mM NADP+; cosubstrate NADP+ | 18.4 | 0.004 | 3454 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, succinic semialdehyde |
| succinic semialdehyde dehydrogenase SSADH-II | Sulfolobus solfataricus | succinic semialdehydeNADH formation at 340 nm; 5 mM NAD+; cosubstrate NAD+ | 16.8 | 0.001 | 1789 | pH 6.5, 70 °C | PMID 23296511 | Open record: succinic semialdehyde dehydrogenase SSADH-II, succinic semialdehyde |