CatLogenzyme kinetics catalog

EC 1.2.1.5: aldehyde dehydrogenase [NAD(P)+]

OxidoreductasesOpen in Browse

CatLog read 81 records for EC 1.2.1.5 from 8 papers, for 6 organisms. Names in these papers: aldehyde dehydrogenase (BcALDH), cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible), aldehyde dehydrogenase (BlALDH), Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase) and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 107 records for EC 1.2.1.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.2.1.5 in Browse.

Papers

PaperOrganismsRecords
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistanceHomo sapiens21
Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereusBacillus cereus15
Inducible aldehyde dehydrogenases from rat liver cytosolRattus norvegicus14
Gene cloning and biochemical characterization of a NAD(P)+ -dependent aldehyde dehydrogenase from Bacillus licheniformisBacillus licheniformis12
Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenasesHomo sapiens6
Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiaeSaccharomyces cerevisiae6
Substituent effects during the rat liver aldehyde dehydrogenase catalyzed oxidation of aromatic aldehydesyeast4
Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1Homo sapiens3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
aldehyde dehydrogenaseyeast2-Bromobenzaldehyde—0.016—pH 9.6, 22 °CPMID 3300781Open
aldehyde dehydrogenaseyeast2-Chlorobenzaldehyde—0.017—pH 9.6, 22 °CPMID 3300781Open
aldehyde dehydrogenaseyeast2-Fluorobenzaldehyde—0.0165—pH 9.6, 22 °CPMID 3300781Open
aldehyde dehydrogenaseyeastBenzaldehyde—0.013—pH 9.6, 22 °CPMID 3300781Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusacetaldehyde0.180.0951.85pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusall-trans-retinal0.00470.0070.67pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusall-trans-retinal0.0020.130.015pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusbenzaldehyde0.220.21.08pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusnicotinamide adenine dinucleotide (oxidized)0.00170.0040.42pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusnicotinamide adenine dinucleotide phosphate (oxidized)0.00180.00420.43pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)Bacillus cereusnicotinamide adenine dinucleotide phosphate (reduced)5.5 × 10⁻⁴0.040.0138pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant C300ABacillus cereusall-trans-retinal6.7 × 10⁻⁴0.0380.018pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant C300SBacillus cereusall-trans-retinal6.7 × 10⁻⁴0.00370.157pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant C300SBacillus cereusall-trans-retinal6.7 × 10⁻⁴0.420.0013pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant E194SBacillus cereusall-trans-retinal0.0050.010.5pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant E194SBacillus cereusall-trans-retinal0.00650.0290.23pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant E266ABacillus cereusall-trans-retinal0.00120.920.0012pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant E457VBacillus cereusall-trans-retinal0.02570.006254.1pH 7, 37 °CPMID 27107124Open
aldehyde dehydrogenase (BcALDH)variant E457VBacillus cereusall-trans-retinal0.00380.0340.1127pH 7.5, 40 °CPMID 27107124Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformis3-methylbutanalcosubstrate NAD+3.589.870.36pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformis3-methylbutanalcosubstrate NADP+0.9110.780.09pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisacetaldehydecosubstrate NAD+4.4618.890.24pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisacetaldehydecosubstrate NADP+1.11393.40.003pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisbutanalcosubstrate NAD+32.82.9511.89pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisbutanalcosubstrate NADP+11.54.932.39pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisNAD+57.640.15392.9pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformisNADP+20.971.1218.77pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformispentanalcosubstrate NAD+30.990.12257.0pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformispentanalcosubstrate NADP+19.410.3456.66pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformispropanalcosubstrate NAD+49.380.46107.5pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase (BlALDH)Bacillus licheniformispropanalcosubstrate NADP+13.360.6520.67pH 7, 37 °CPMID 20495892Open
aldehyde dehydrogenase ALDH3B1Homo sapienshexadecanal—0.0456—pH 8.5, 37 °CPMID 23721920Open
aldehyde dehydrogenase ALDH3B1Homo sapiensoctanal—0.025—pH 8.5, 37 °CPMID 23721920Open
aldehyde dehydrogenase ALDH3B1Homo sapienstrans-2-hexadecenal—0.0049—pH 8.5, 37 °CPMID 23721920Open
ALDH2Saccharomyces cerevisiaeacetaldehyde—0.01—pH 7.4PMID 9473035Open
ALDH2Saccharomyces cerevisiaeNAD+—1.1—pH 7.4PMID 9473035Open
ALDH2Saccharomyces cerevisiaeNADP+propionaldehyde fixed at 0.28 mM—0.447—pH 7.4PMID 9473035Open
ALDH2Saccharomyces cerevisiaeNADP+acetaldehyde fixed at 0.18 mM; cosubstrate acetaldehyde—1.4—pH 7.4PMID 9473035Open
ALDH2Saccharomyces cerevisiaepropionaldehydeNADP fixed at 15 mM; cosubstrate NADP—0.017—pH 7.4PMID 9473035Open
ALDH2Saccharomyces cerevisiaepropionaldehydeNAD fixed at 20 mM; cosubstrate NAD—0.013—pH 7.4PMID 9473035Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)Homo sapiensbenzaldehyde0.90.224.1 calc.pH 7.4, 25 °CPMID 10548037Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)Homo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)—0.0078—pH 7.4, 25 °CPMID 10548037Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)Homo sapiensp-nitrophenyl acetate1.430.27.2 calc.pH 7.4, 25 °CPMID 10548037Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)variant E209QHomo sapiensbenzaldehyde0.780.581.4 calc.pH 7.4, 25 °CPMID 10548037Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)variant E209QHomo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)—0.061—pH 7.4, 25 °CPMID 10548037Open
class 3 aldehyde dehydrogenase (hALDH3, human stomach ALDH3)variant E209QHomo sapiensp-nitrophenyl acetate46.80.59 calc.pH 7.4, 25 °CPMID 10548037Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicus3-acetylpyridine adenine dinucleotide—0.425—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicus4-methoxybenzaldehyde—0.01—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicus4-nitrobenzaldehyde—0.0046—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusAcetaldehyde—12.14—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusBenzaldehyde—0.124—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusButyraldehyde—6.347—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusDecanal—0.126—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusHeptanal—0.515—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusHexadecanal—0.174—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusindole-3-acetaldehyde—0.147—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusNAD+—0.0675—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusNADP+—1.41—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusnicotinamide hypoxanthine dinucleotide (deamino-NAD+)—0.0168—pH 7.2PMID 4002223Open
cytosolic aldehyde dehydrogenase, tau (τ) isozyme (TCDD-inducible)Rattus norvegicusPropionaldehyde—5.472—pH 7.2PMID 4002223Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensacetaldehyde1.0 mM NAD fixed; cosubstrate NAD—80—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensacetaldehyde4.0 mM NADP fixed; cosubstrate NADP—81—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensbenzaldehyde1.0 mM NAD fixed; cosubstrate NAD—0.505—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensbenzaldehyde4.0 mM NADP fixed; cosubstrate NADP—0.486—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensNAD—0.054—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensNADP—1—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensoctanal1.0 mM NAD fixed; cosubstrate NAD—0.113—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapiensoctanal4.0 mM NADP fixed; cosubstrate NADP—0.104—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapienspropanal1.0 mM NAD fixed; cosubstrate NAD—19.06—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapienspropanal4.0 mM NADP fixed; cosubstrate NADP—19—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapienspyridine-4-carbaldehyde1.0 mM NAD fixed; cosubstrate NAD—0.19—pH 8.1, 37 °CPMID 8328987Open
Type-1 ALDH-3 (stomach mucosa class 3 aldehyde dehydrogenase)Homo sapienspyridine-4-carbaldehyde4.0 mM NADP fixed; cosubstrate NADP—0.19—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensaldophosphamide—0.64—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensbenzaldehyde1.0 mM NAD fixed; cosubstrate NAD—0.64—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensbenzaldehyde4.0 mM NADP fixed; cosubstrate NADP—0.64—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensNAD—0.55—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensNADP—0.94—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensoctanal1.0 mM NAD fixed; cosubstrate NAD—0.067—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapiensoctanal4.0 mM NADP fixed; cosubstrate NADP—0.067—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapienspyridine-4-carbaldehyde1.0 mM NAD fixed; cosubstrate NAD—0.091—pH 8.1, 37 °CPMID 8328987Open
Type-2 ALDH-3 (MCF-7/OAP class 3 aldehyde dehydrogenase)Homo sapienspyridine-4-carbaldehyde4.0 mM NADP fixed; cosubstrate NADP—0.091—pH 8.1, 37 °CPMID 8328987Open